Search results for "Risk"

showing 10 items of 9963 documents

Renal disease associated with myeloproliferative neoplasms and myelodysplastic syndrome/myeloproliferative neoplasms

2020

Aims Renal changes in patients with myeloproliferative neoplasms (MPNs) or myelodysplastic syndrome (MDS)/MPNs have been addressed by few, respectively no, reports. The aim of this study was to focus on a systematic evaluation of renal biopsies in patients with MPNs or MDS/MPNs. Methods and results The cohort comprised 29 patients (23 men) aged 67 ± 11 years (mean ± standard deviation), diagnosed with chronic myeloid leukaemia (n = 5), polycythaemia vera (n = 9), primary myelofibrosis (n = 5), essential thrombocythaemia (n = 2), or chronic myelomonocytic leukaemia (n = 4), as well as MPNs or MDS/MPNs not otherwise specified (n = 4). Patients manifested with proteinuria (93%), partially in t…

AdultMale0301 basic medicinemedicine.medical_specialtyPolycythaemiaHistologyThrombotic microangiopathy610 MedizinRenal functionMesangial hypercellularityGastroenterologyPathology and Forensic MedicineNephropathyCohort Studies03 medical and health sciencesGlomerulonephritis0302 clinical medicineRisk FactorsNeoplasmshemic and lymphatic diseasesInternal medicine610 Medical sciencesmedicineHumansddc:610MyelofibrosisAgedAged 80 and overMyeloproliferative DisordersProteinuriaThrombotic Microangiopathiesbusiness.industryGlomerulonephritisGeneral MedicineMiddle Agedmedicine.diseaseMyelodysplastic-Myeloproliferative Diseases030104 developmental biologyMyelodysplastic Syndromes030220 oncology & carcinogenesisFemaleKidney Diseasesmedicine.symptombusiness
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The Prognostic Value of Renal Function in Acute Pulmonary Embolism—A Multi-Centre Cohort Study

2018

Background Haemodynamic alterations caused by acute pulmonary embolism (PE) may affect multi-organ function including kidneys. This multi-centre, multinational cohort study aimed to validate the prognostic significance of estimated glomerular filtration rate (eGFR) and its potential additive value to the current PE risk assessment algorithms. Methods The post hoc analysis of pooled prospective cohort studies: 2,845 consecutive patients (1,424 M/1,421 F, 66 ± 17 years) with confirmed acute PE and followed up for 180 days. We tested prognostic value of pre-specified eGFR level ≤60 mL/min/1.73 m2 calculated on admission according to the Modification of Diet in Renal Disease study equation. Th…

AdultMale0301 basic medicinemedicine.medical_specialtymedicine.medical_treatmentEmbolectomyRenal functionHemorrhage030204 cardiovascular system & hematologyKidney Function TestsRisk Assessment03 medical and health sciences0302 clinical medicineInternal medicinemedicineHumansProspective cohort studyStrokeAgedProportional Hazards Modelsbusiness.industryHemodynamicsHematologyThrombolysisMiddle AgedPrognosismedicine.diseaseConfidence interval3. Good healthPulmonary embolismTreatment Outcome030104 developmental biologyFemalePulmonary EmbolismbusinessAlgorithmsBiomarkersGlomerular Filtration RateCohort studyThrombosis and Haemostasis
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Development and Psychometric Properties of the Detection of Sexual Abuse Risk Screening Scale (DSARss).

2019

People with intellectual disability (ID) are more vulnerable to being victims of sexual abuse (SA) because, in most cases, they are not able to detect the warning signs that abuse could occur. However, there is a lack of appropriate assessment tools to determine their vulnerability. To address this limitation, the current study tests the psychometric properties of the Detection of Sexual Abuse Risk Screening Scale (DSARss), a new scale developed to assess the ability of individuals with mild or moderate ID to detect the risk of SA. In all, 246 individuals with mild or moderate ID (55.3% males) completed the DSARss, along with other scales assessing related dimensions (e.g., psychopathologi…

AdultMale030506 rehabilitationPsychometricsVulnerabilitysexual abusepsychometric propertiesSeverity of Illness Index03 medical and health sciencesDisability EvaluationIntellectual DisabilitySurveys and QuestionnairesIntellectual disabilitymedicineHumans0501 psychology and cognitive sciencesGeneral PsychologyCrime Victims05 social sciencesSex Offensesrisk assessmentReproducibility of ResultsMiddle Agedmedicine.diseaseExploratory factor analysisPsychiatry and Mental healthRisk screeningSexual abuseintellectual disabilityScale (social sciences)Female0305 other medical scienceRisk assessmentPsychology050104 developmental & child psychologyClinical psychologyPsychopathologySexual abuse : a journal of research and treatment
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The Prevalence of Sexual Violence: Results From a Population-Based Sample

2016

BACKGROUND: Sexual violence can cause severe mental and bodily harm. This is the first study of a population-based sample in Germany to assess both the frequency of the subjects' having experienced sexual violence and the frequency of their having manifested sexually aggressive behavior themselves. METHODS: 2513 persons (of whom 2422 were over age 18 and 91 were aged 14 to 18) were asked about their experiences with sexual violence in the past 12 months, either as the person committing sexual violence or as the victim of sexual violence at the hands of other adults or similarly aged adolescents. RESULTS: 0.6% (n = 6) of the men and 1.2% (n = 16) of the women surveyed, and ca. 5% (n = 4) of …

AdultMale050103 clinical psychologymedicine.medical_specialtyAdolescentPopulationPoison control050109 social psychologySuicide preventionOccupational safety and healthYoung AdultAge DistributionRisk FactorsGermanyInjury preventionPrevalenceHumansMedicine0501 psychology and cognitive sciencesSex DistributionPsychiatryeducationCrime VictimsAgedAged 80 and overeducation.field_of_studySexual violencebusiness.industrySex Offenses05 social sciencesHuman factors and ergonomicsGeneral MedicineMiddle AgedCrime statisticsOriginal ArticleFemalebusinessClinical psychologyDeutsches Ärzteblatt international
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Dropout from Court-Mandated Intervention Programs for Intimate Partner Violence Offenders: The Relevance of Alcohol Misuse and Cognitive Impairments

2019

There is considerable interest in offering insight into the mechanisms that might explain why certain perpetrators of intimate partner violence against women (IPVAW) drop out of interventions. Although several socio-demographic variables and attitudes towards IPVAW have been proposed as risk factors for IPVAW perpetrators&rsquo

AdultMale050103 clinical psychologymedicine.medical_specialtyHealth Toxicology and Mutagenesisintimate partner violencePsychological interventionlcsh:MedicinedropoutArticle03 medical and health sciences0302 clinical medicineBehavior TherapyRisk FactorsIntervention (counseling)medicineHumansCognitive Dysfunction0501 psychology and cognitive sciencesPsychiatryempathyDropout (neural networks)Consumption (economics)recidivismRecidivismalcohollcsh:R05 social sciencesPublic Health Environmental and Occupational HealthCognitionDiscontinuationAttitudeParellaDomestic violenceFemaleAlcoholPsychologyAlcohol-Related Disorders030217 neurology & neurosurgeryInternational Journal of Environmental Research and Public Health
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Changes in Alcohol Consumption Pattern Based on Gender during COVID-19 Confinement in Spain

2021

(1) The goal of this study was to analyze the prevalence and pattern of alcohol consumption (frequency of consumption, average daily consumption, and risky consumption) before and during confinement due to the coronavirus disease (COVID-19) in the adult population and based on gender. (2) Methods: Data from 3779 individuals were collected via a set of online surveys. The AUDIT alcohol consumption questions (AUDIT-C) were used to measure the frequency of consumption, the average daily consumption, intensive consumption, risky consumption, and standard drink units. (3) Results: During confinement, the prevalence of alcohol consumption declined in both males and females, but only intensive con…

AdultMale2019-20 coronavirus outbreakmedicine.medical_specialty6114.06 Comportamiento del ConsumidorCoronavirus disease 2019 (COVID-19)Alcohol DrinkingHealth Toxicology and Mutagenesis3309.01 Bebidas Alcohólicasrisk consumptionHealth BehaviorAdult populationFrequency of use030508 substance abusestandard drink unit (SDU)Article03 medical and health sciences0302 clinical medicine6302.02 Psicología SocialSurveys and QuestionnairesgenderMedicineHumans030212 general & internal medicineConsumption (economics)business.industryalcoholSARS-CoV-2Public healthPublic Health Environmental and Occupational HealthRCOVID-19confinement measures63 SociologíaStandard drinkSpainMedicineFemale0305 other medical sciencebusinessAlcohol consumptionDemographyInternational Journal of Environmental Research and Public Health
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''Sex Difference In Open-water Ultra-swim Performance In the Longest Freshwater Lake Swim In Europe''

2013

Eichenberger, Evelyn | Knechtle, Beat | Knechtle, Patrizia | Ruest, Christoph A. | Rosemann, Thomas | Lepers, Romuald | Senn, Oliver; International audience; ''This study examined participation and performance trends in the 26.4-km open-water ultra-swim "Marathon Swim in Lake Zurich," Switzerland. A total of 461 athletes (157 women and 304 men) finished the race between 1987 and 2011. The mean age of the finishers during the studied period was 32.0 +/- 6.5 years for men and 30.9 +/- 7.2 years for women. The mean age of finishers and the age of winners increased significantly across years for both sexes (p 0.05). The swimming time performance remained stable (p > 0.05) for both sexes across …

AdultMaleANTHROPOMETRY''RACE PERFORMANCEAMERICA''Physical Therapy Sports Therapy and RehabilitationFresh WaterBiologyAthletic Performance03 medical and health sciencesCOLD-WATER0302 clinical medicineSex FactorsAGENegatively associatedMARATHONHumansOrthopedics and Sports Medicine14. Life underwater030212 general & internal medicineAMERICAPHYSIOLOGYSwimmingHYPOTHERMIA[SCCO.NEUR]Cognitive science/NeuroscienceAge FactorsTemperatureRACE PERFORMANCEMean age030229 sport sciencesGeneral MedicineOdds ratioAnthropometryThermoregulation6. Clean waterIncreased riskOpen waterLogistic ModelsWater temperatureMultivariate Analysis[ SCCO.NEUR ] Cognitive science/NeuroscienceFemaleGENDERhuman activitiesSwitzerlandENDURANCE SWIMMERSDemography
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Incidence of symptomatic venous thromboembolism following hospitalization for coronavirus disease 2019: Prospective results from a multi-center study

2021

Background Thrombosis and pulmonary embolism appear to be major causes of mortality in hospitalized coronavirus disease 2019 (COVID-19) patients. However, few studies have focused on the incidence of venous thromboembolism (VTE) after hospitalization for COVID-19. Methods In this multi-center study, we followed 1529 COVID-19 patients for at least 45 days after hospital discharge, who underwent routine telephone follow-up. In case of signs or symptoms of pulmonary embolism (PE) or deep vein thrombosis (DVT), they were invited for an in-hospital visit with a pulmonologist. The primary outcome was symptomatic VTE within 45 days of hospital discharge. Results Of 1529 COVID-19 patients discharge…

AdultMaleARDSmedicine.medical_specialtyTime FactorsDeep veinIran030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineRisk FactorsFull Length ArticleInternal medicinemedicineHumansProspective Studiescardiovascular diseasesMyocardial infarctionThromboprophylaxisStrokeAgedAged 80 and overVenous Thrombosisbusiness.industryIncidenceIncidence (epidemiology)COVID-19Venous ThromboembolismHematologyMiddle Agedmedicine.diseaseThrombosisPatient DischargePulmonary embolismHospitalizationmedicine.anatomical_structure030220 oncology & carcinogenesisHeart failureFemaleCohort studyPulmonary EmbolismbusinessThrombosis Research
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Testing Individual Risk of Acute Mountain Sickness at Greater Altitudes

2009

The assessment of an individual's degree of acclimatization to altitude is difficult. This is particularly applicable to military operations that have to be performed at altitude. This study describes a new and simple test that allows for the determination of an individual's risk for high-altitude illness at higher altitudes. The prediction is based on the lowest oxygen saturation (SaO2) found during an uphill run at high altitude (11,060 ft [3,371 m]), combined with the time needed to complete the run. The test results were compared against the severity of high-altitude symptomatology on the summit of Mont Blanc (15,762 ft [4,808 m]). The main outcome was the significant correlation betwee…

AdultMaleAcclimatizationAltitude SicknessIndividual riskRisk AssessmentStatistics NonparametricRunningOxygen ConsumptionAltitudePredictive Value of TestsGermanySurveys and QuestionnairesTask Performance and AnalysisHumansMedicineOximetryMont blancOxygen saturation (medicine)business.industryAltitudePublic Health Environmental and Occupational HealthGeneral MedicineEffects of high altitude on humansMountaineeringMilitary PersonnelbusinessDemographyMilitary Medicine
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Association between antithrombotic treatment and outcomes at 1-year follow-up in patients with atrial fibrillation: the EORP-AF General Long-Term Reg…

2019

Aims In recent years, stroke prevention in patients with atrial fibrillation (AF) has radically changed, with increasing use of non-vitamin K antagonist oral anticoagulants (NOACs). Contemporary European data on AF thromboprophylaxis are needed. Methods and results We report 1-year follow-up data from the EURObservational Research Programme in Atrial Fibrillation (EORP-AF) General Long-Term Registry. Outcomes were assessed according to antithrombotic therapy. At 1-year follow-up, 9663 (88.0%) patients had available data for analysis: 586 (6.1%) were not treated with any antithrombotic; 681 (7.0%) with antiplatelets only; 4066 (42.1%) with vitamin K antagonist (VKA) only; 3167 (32.8%) with …

AdultMaleAcute coronary syndromemedicine.medical_specialtymedicine.drug_classHemorrhageOutcomes030204 cardiovascular system & hematologyLower riskRisk Assessment[SHS]Humanities and Social Sciences03 medical and health sciences0302 clinical medicineFibrinolytic AgentsRisk FactorsPhysiology (medical)Internal medicineCause of DeathAntithromboticMedicineHumans030212 general & internal medicineProspective StudiesRegistriesPractice Patterns Physicians'StrokeAgedEORP-AF registryAged 80 and overAntithrombotic therapybusiness.industryProportional hazards modelAtrial fibrillationVitamin K antagonistMiddle Agedmedicine.diseaseAtrial fibrillationObservational registriesEuropeStrokeFemaleCardiology and Cardiovascular MedicinebusinessAntithrombotic therapy; Atrial fibrillation; EORP-AF registry; Observational registries; Outcomes; StrokeFibrinolytic agentFollow-Up Studies
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