Search results for "Rite"
showing 10 items of 2726 documents
Cloning of sponge heat shock proteins: evolutionary relationships between the major kingdoms
2009
In the present study we have cloned from sponges (Porifera) those molecules which are involved in the protection of organisms against physiological and stress conditions; the inducible heat shock protein Mr 70,000, hsp70, from the marine sponge Geodia cydonium, its interacting hsp40, a DnaJ-like protein (from G. cydonium) and the constitutively expressed counterpart the glucose-regulated protein Mr 78,000, GRP78 from Suberites domuncula. Alignments of the sequences revealed that the deduced aa sequences of all sponge hsp's share high homology to other metazoan sequences, and are separated from related sequences from plants and fungi (hsp70, GRP78, DnaJ) as well as Bacteria (DnaK, the hsp70 …
Bayesian versus data driven model selection for microarray data
2014
Clustering is one of the most well known activities in scientific investigation and the object of research in many disciplines, ranging from Statistics to Computer Science. In this beautiful area, one of the most difficult challenges is a particular instance of the model selection problem, i.e., the identification of the correct number of clusters in a dataset. In what follows, for ease of reference, we refer to that instance still as model selection. It is an important part of any statistical analysis. The techniques used for solving it are mainly either Bayesian or data-driven, and are both based on internal knowledge. That is, they use information obtained by processing the input data. A…
Tetti verdi multistrato per lo sviluppo sostenibile di città resilienti: quattro casi studio italiani
2021
Negli ultimi anni le inondazioni in ambito urbano sono state sempre più frequenti, provocando notevoli danni sia livello sociale che a livello economico. Questo fenomeno è in parte determinato da un aumento di urbanizzazione causato dalla crescita della popolazione, che tende sempre più a spostarsi dalle zone rurali alle aree urbane, che si espandono molto velocemente, spesso con infrastrutture idrauliche inadeguate. Inoltre, a causa di cambiamenti climatici, soprattutto nelle aree mediterranee, si può osservare un aumento di lunghi periodi di siccità, intervallati da piogge di breve durata, ma di sempre più forte intensità e frequenza. La presenza di questi fenomeni di pioggia intensa, in …
Emergenze-urgenze urologiche e dell'apparato genitale maschile
2020
EMATURIA - Il termine “ematuria” indica la presenza di globuli rossi (GR) nelle urine. Può essere visibile a occhio nudo (macroematuria o ematuria macroscopica) o solo al microscopio (microematuria)5 LA COLICA RENALE - La colica reno-ureterale, nella sua manifestazione tipica, è un dolore acuto che dalla regione lombare s’irradia, anteriormente, al fianco e alla regione inguinale omolaterale (fino al testicolo nell’uomo, alle grandi labbra nelle donne). Talvolta si associa a nausea e vomito, ematuria e sintomi disurici (similcistitici). Ha una durata variabile da alcuni minuti ad alcune ore. L’alvo può essere temporaneamente chiuso ai gas. Eventuali brividi e febbre indicano un’infezione se…
An interactive approach to multiple criteria optimization with multiple decision-makers
1986
In this article we propose a formal man-machine interactive approach to multiple criteria optimization with multiple decision makers. The approach is based on some of our earlier research findings in multiple criteria decision making. A discrete decision space is assumed. The same framework may readily be used for multiple criteria mathematical programming problems. To test the approach two experiments were conducted using undergraduate Business School students as subjects in Finland and in the United States. The context was, respectively, a high-level Finnish labor-management problem and the management-union collective bargaining game developed at the Krannert Graduate School of Management…
Sources and Boundaries of Institutional and Linguistic Normativity. Towards a Critical Social Ontology.
2013
Since Hegel and until speech acts theory and contemporary social ontology it came to full development the idea that most of reasons, duties, rights, entitlements, have to do, against Kant, with our participation to social, linguistic and institutional practices of the lifeform to which we belong rather than or more than with our dealing with “substantive moral principles”. But if we accept, with Hegel, that every individual rational determination of the will is justified as such only as a part of our collective Sittlichkheit (Hegel, 1967, cf. Di Lorenzo Ajello, 2009); if we accept from speech acts theory that there are commitments, rights and entitlements specific to every type of speech ac…
Molecular Classification of N-Aryloxazolidinone-5-carboxamides as Human Immunodeficiency Virus Protease Inhibitors
2015
Algorithms for classification and taxonomy are proposed in this chapter based information entropy (IE) and its production. The 38 N- aryloxazolidinone-5-carboxamides (NCAs), for human immunodeficiency virus (HIV) protease (PR) inhibition, are classified using seven characteristic chemical properties of different moieties: R 1/2 , R 3–6 on different phenyls and R 7 . Many classification algorithms are based on IE. When applying some procedures to moderate-sized sets, excessive number of results appear compatible with the data and suffer combinatorial explosion. However, after the equipartition conjecture (EC), one has a selection criterion among different variants that results from classifi…
Molecular Classification of 5-Amino-2-Aroylquinolines and 4-Aroyl-6,7,8-Trimethoxyquinolines as Highly Potent Tubulin Polymerization Inhibitors
2013
Algorithms for classification and taxonomy are proposed based on criteria as information entropy and its production. It is classified a series of 5-amino-2-aroylquinolines (AAQs) and 4-aroyl-6,7,8-trimethoxyquinolines (TMQs) combretastatin analogues for anti-cancer activity. 5-Amino-6-methoxy-2-aroylquinoline AAQ showed anti-proliferative activity more potent as compared to combretastatin A-4 (CA4), against various human cancer cell lines and a multidrug resistance (MDR) cancer cell line. On the basis of AAQ/TMQ structure–activity relationship new derivatives are designed. The AAQs/TMQs are classified using nine characteristic chemical properties in molecules. Many classification algorithms…
Recensione: MR2928500 Cascales, Bernardo; Kalenda, Ondřej F. K.; Spurný, Jiří A quantitative version of James's compactness theorem. Proc. Edinb. Mat…
2013
Paper review
Monitoring multidimensional phenomena with a multicriteria composite performance interval approach
2021
[EN] In the last two decades, the construction of composite indicators to measure and compare multidimensional phenomena in a broad spectrum of domains has increased considerably. Different methodological approaches are used to summarise huge datasets of information in a single figure. This paper proposes a new approach that consists in computing a multicriteria composite performance interval based on different aggregation rules. The suggested approach provides an additional layer of information as the performance interval displays a lower bound from a non-compensability perspective, and an upper bound allowing for full-compensability. The outstanding features of this proposal are: 1) a dis…