Search results for "River"
showing 10 items of 564 documents
Prognostic vs predictive molecular biomarkers in colorectal cancer: is KRAS and BRAF wild type status required for anti-EGFR therapy?
2010
An important molecular target for metastatic CRC treatment is the epidermal growth factor receptor (EGFR). Many potential biomarkers predictive of response to anti-EGFR monoclonal antibodies (cetuximab and panitumumab) have been retrospectively evaluated, including EGFR activation markers and EGFR ligands activation markers. With regard to the "negative predictive factors" responsible for primary or intrinsic resistance to anti-EGFR antibodies a lot of data are now available. Among these, KRAS mutations have emerged as a major predictor of resistance to panitumumab or cetuximab in the clinical setting and several studies of patients receiving first and subsequent lines of treatment have sho…
Lotus spp: biotechnological strategies to improve the bioeconomy of lowlands in the Salado River Basin (Argentina)
2016
The Salado River Basin region is the most important livestock breeding area in Argentina, wherethe Lotus species has been traditionally cultivated as forages. Nearly 60% of their land surface is dominated by salt-affected soils with severe constraints for crop cultivation. In order to cope with that limitation, farmers have utilized species such as non-native L. tenuis (ex- Lotus glaber), which shows a very good adaptation. As a result, inter-seeding of L. tenuis has been proposed as a strategy of choice for improving forage production in marginal areas. The increase in soil quality by these means is achieved by an increment of the organic matter content, improvement of soil fertility as we…
Vertebrate and Miospore Assemblages from the Famennian of North Timan (Upper Devonian, Russia)
2014
The Upper Devonian vertebrate and miospore assemblages from the Volonga River section of the upper part of the Pokayama Formation from North Timan are described for the first time. The middle Famennian age of the unit is confirmed by miospore data. The correlation of some East European sections is discussed.
Effect of catchment characteristics on aquatic carbon export from a boreal catchment and its importance in regional carbon cycling
2013
Inland waters transport and emit into the atmosphere large amounts of carbon (C), which originates from terrestrial ecosystems. The effect of land cover and land-use practises on C export from terrestrial ecosystems to inland waters is not fully understood, especially in heterogeneous landscapes under human influence. We sampled for dissolved C species in five tributaries with well-determined subcatchments (total size 174.5 km(2)), as well as in various points of two of the subcatchments draining to a boreal lake in southern Finland over a full year. Our aim was to find out how land cover and land-use affect C export from the catchments, as well as CH4 and CO2 concentrations of the streams,…
Determinants of performance drivers in online food delivery platforms: a dynamic performance management perspective
2022
PurposeThis study aims to demonstrate that the Dynamic Performance Management (DPM) framework, integrating performance management with system dynamics modelling, enables decision-makers to identify sustainable strategies in online food delivery platforms, thereby avoiding company failure.Design/methodology/approachThis study undertakes a multistep methodological approach. After the literature review, a retrospective case study approach was used. To build the DPM framework and the system dynamics simulation model, primary and secondary data were collected and analysed.FindingsThis study by adopting the DPM perspective highlights the critical role performance drivers play to assess the viabil…
Forjando “líderes”. Estrategias persuasivas en los discursos de Pilar Primo de Rivera
2021
Se examinan todos aquellos mecanismos persuasivos que conforman el entramado argumental del discurso de la fundadora de la Sección Femenina. En concreto, se han seleccionado los primeros cuatro discursos pronunciados a las militantes durante los Congresos Nacionales de la Sección Femenina, entre 1937 (Salamanca) y 1940 (Zamora), es decir, aquellos que se celebran durante la Guerra Civil e inmediatamente después de la conclusión del conflicto, con el objetivo de investigar si el restablecimiento de la paz y el orden influye de alguna manera en el tono, los argumentos o el grado de modalización del enunciado.
Toxicokinetics of xenobiotics in zebrafish—Comparison between tap and river water
1991
Abstract 1. 1. Uptake and elimination of lindane, 3,4-dichloroaniline, phenol and 4-nitrophenol by the zebrafish Brachydanio rerio were investigated in tap water and in water of the river Rhine. 2. 2. The differences in bioconcentration of chemicals between the two water types did not exceed a factor of 2.5. 3. 3. Elimination kinetics were comparable in tap and river water. 4. 4. It can be concluded that water of the river Rhine does not influence the kinetics of the investigated xenobiotics.
Analiza stanu świadomości zagrożenia zjawiskiem powodzi na obszarze zlewni rzeki Biała Głuchołaska
2016
Celem pracy było zbadanie poziomu świadomości dotyczącej powodzi wśród osób zamieszkujących zlewnię transgranicznej rzeki Biała Głuchołaska. Empiryczną analizę przeprowadzono za pomocą ankiety w grupie około 300 osób. Wśród ankietowanych wyróżniono sześć grup wiekowych. Respondenci udzielili odpowiedzi na 25 pytań. Ankieta stanowiła narzędzie do określenia poziomu wiedzy z zakresu zabezpieczeń przeciwpowodziowych, systemów ostrzegania, zachowania się w czasie powodzi i częstości jej występowania oraz strat, jakie ze sobą niesie, przygotowania służb reagowania do powodzi, ogólnego poziomu obawy przed powodzią, stopnia przygotowania ludności do wystąpienia powodzi oraz ochrony przeciwpowodzio…
Origin of the natural variation in the storage of dietary carotenoids in freshwater amphipod crustaceans
2020
16 pages; International audience; Carotenoids are diverse lipophilic natural pigments which are stored in variable amounts by animals. Given the multiple biological functions of carotenoids, such variation may have strong implications in evolutionary biology. Crustaceans such as Gammarus amphipods store large amounts of these pigments and inter-population variation occurs. While differences in parasite selective pressure have been proposed to explain this variation, the contribution of other factors such as genetic differences in the gammarid ability to assimilate and/or store pigments, and the environmental availability of carotenoids cannot be dismissed. This study investigates the relati…
Receiving water body quality assessment: an integrated mathematical approach applied to an Italian case study
2011
This study presents a basin-scale approach to the analysis of receiving water body quality considering both point and non-point pollution sources. In particular, this paper describes an extensive data gathering campaign carried out in the Nocella catchment, which is an agricultural and semi-urbanised basin located in Sicily, Italy. Two sewer systems, two wastewater treatment plants and a river reach were monitored during both dry and wet weather periods. A mathematical model of the entire integrated system was also created. Specifically, a detailed modelling approach was developed by employing three well known models: Storm Water Management Model, GPS-X and Soil and Water Assessment Tool. T…