Search results for "Roca"

showing 10 items of 1893 documents

Pharmacological blockade of the fatty acid amide hydrolase (FAAH) alters neural proliferation, apoptosis and gliosis in the rat hippocampus, hypothal…

2015

Endocannabinoids participate in the control of neurogenesis, neural cell death and gliosis. The pharmacological effect of the fatty acid amide hydrolase (FAAH) inhibitor URB597, which limits the endocannabinoid degradation, was investigated in the present study. Cell proliferation (phospho-H3(+) or BrdU(+) cells) of the main adult neurogenic zones as well as apoptosis (cleaved caspase-3(+)), astroglia (GFAP(+)), and microglia (Iba1(+) cells) were analyzed in the hippocampus, hypothalamus and striatum of rats intraperitoneally treated with URB597 (0.3 mg/kg/day) at one dose/4-days resting or 5 doses (1 dose/day). Repeated URB597 treatment increased the plasma levels of the N-acylethanolamine…

AstrocitosNeurobiologia del desenvolupamentAmidohidrolasasCannabinoid receptorCarbamatos:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Intracellular Signaling Peptides and Proteins::Apoptosis Regulatory Proteins::Caspases [Medical Subject Headings]:Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Differentiation::Neurogenesis [Medical Subject Headings]medicine.medical_treatment:Chemicals and Drugs::Carbohydrates::Monosaccharides::Hexoses::Glucose [Medical Subject Headings]Apoptosis:Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Body Weight [Medical Subject Headings]chemistry.chemical_compound:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Membrane Proteins::Receptors Cell Surface::Receptors G-Protein-Coupled::Receptors Cannabinoid::Receptor Cannabinoid CB1 [Medical Subject Headings]0302 clinical medicine:Chemicals and Drugs::Organic Chemicals::Carboxylic Acids::Acids Acyclic::Carbamates [Medical Subject Headings]Fatty acid amide hydrolaseReceptor cannabinoide CB1:Organisms::Eukaryota::Animals [Medical Subject Headings]FAAHGliosishealth care economics and organizations:Chemicals and Drugs::Nucleic Acids Nucleotides and Nucleosides::Nucleosides::Deoxyribonucleosides::Deoxyuridine::Bromodeoxyuridine [Medical Subject Headings]:Chemicals and Drugs::Lipids::Glycerides::Triglycerides [Medical Subject Headings]Original Research0303 health sciencesNeurogenesisBenzamidas:Chemicals and Drugs::Polycyclic Compounds::Steroids::Cholestanes::Cholestenes::Cholesterol [Medical Subject Headings]Endocannabinoid systemEtanolaminas3. Good healthEndocannabinoides:Chemicals and Drugs::Lipids::Fatty Acids::Fatty Acids Unsaturated::Fatty Acids Monounsaturated::Oleic Acids [Medical Subject Headings]CannabinoidesMicroglíalipids (amino acids peptides and proteins)medicine.symptomColesterol:Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Terpenes::Cannabinoids [Medical Subject Headings]:Chemicals and Drugs::Lipids::Fatty Acids::Palmitic Acids [Medical Subject Headings]psychological phenomena and processesProliferación celularmedicine.medical_specialtyCerebroNeurogenesiseducationBiologyBromodesoxiuridina:Anatomy::Nervous System::Neuroglia::Microglia [Medical Subject Headings]Triglicéridoslcsh:RC321-571Ácidos oléicosRatas03 medical and health sciencesCellular and Molecular NeuroscienceInternal medicineHipocampomedicineCaspasa 3:Anatomy::Nervous System::Central Nervous System::Brain::Limbic System::Hippocampus [Medical Subject Headings]:Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Growth Processes::Cell Proliferation [Medical Subject Headings]lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry030304 developmental biologyPalmitoylethanolamide:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Neurotransmitter Agents::Endocannabinoids [Medical Subject Headings]:Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Amidohydrolases [Medical Subject Headings]Cannabinoids:Anatomy::Cells::Neuroglia::Astrocytes [Medical Subject Headings]Peso corporalEnergy metabolism:Anatomy::Nervous System::Central Nervous System::Brain [Medical Subject Headings]:Anatomy::Nervous System::Central Nervous System::Brain::Limbic System::Hypothalamus [Medical Subject Headings]URB597:Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death [Medical Subject Headings]:Diseases::Pathological Conditions Signs and Symptoms::Pathologic Processes::Gliosis [Medical Subject Headings]:Chemicals and Drugs::Organic Chemicals::Amines::Amino Alcohols::Ethanolamines [Medical Subject Headings]Muerte celular:Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death::Apoptosis [Medical Subject Headings]:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats [Medical Subject Headings]EndocrinologyURB597chemistryGliosisnervous systemGlucosaCannabinoidEnergy Metabolism:Chemicals and Drugs::Organic Chemicals::Amides::Benzamides [Medical Subject Headings]HipotálamoÁcidos palmíticos030217 neurology & neurosurgeryNeuroscienceFrontiers in Cellular Neuroscience
researchProduct

Urban organic aerosol composition in eastern China differs from north to south:Molecular insight from a liquid chromatography-mass spectrometry (Orbi…

2021

Air pollution by particulate matter in China affects human health, the ecosystem and the climate. However, the chemical composition of particulate aerosol, especially of the organic fraction, is still not well understood. In this study, particulate aerosol samples with a diameter of ≤2.5 µm (PM2.5) were collected in January 2014 in three cities located in northeast, east and southeast China, namely Changchun, Shanghai and Guangzhou. Organic aerosol (OA) in the PM2.5 samples was analyzed by an ultrahigh-performance liquid chromatograph (UHPLC) coupled to a high-resolution Orbitrap mass spectrometer in both negative mode (ESI-) and positive mode electrospray ionization (ESI+). After non-targe…

Atmospheric ScienceELECTROSPRAY-IONIZATION010504 meteorology & atmospheric sciencesQC1-999Electrospray ionizationCHONAir pollution010501 environmental sciencesmedicine.disease_causeMass spectrometryOXIDATION01 natural sciencesPOLYCYCLIC AROMATIC-HYDROCARBONSPOLLUTIONCHEMISTRYmedicineFIELDQD1-999Chemical compositionEMISSIONS0105 earth and related environmental sciencesSEVERE HAZEChemistryPhysicsORGANOSULFATESParticulatesAerosolChemistryEnvironmental chemistryMass spectrum
researchProduct

The Athena X-ray Integral Field Unit (X-IFU)

2018

著者人数: 23名

Atomic and Molecular Physics and Optic[SDU.ASTR.HE]Sciences of the Universe [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE]Condensed Matter Physics01 natural sciencesAtomic and Molecular Physics and OpticsImaging spectroscopy[SDU.ASTR.IM]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM]010309 opticsX-ray astronomyMicrocalorimeter0103 physical sciencesGeneral Materials ScienceMaterials Science (all)010306 general physicsJournal of Low Temperature Physics
researchProduct

A Theoretical Study of the Low-Lying Excited States of trans- and cis-Urocanic Acid

1999

A multiconfigurational second-order perturbation theory (CASPT2) study of the lowest lying states in the gas-phase electronic spectra of trans- and cis-urocanic acid is presented. Geometries of both isomers have been optimized at the MP2/6-31G(d) and π-CASSCF/ANO-L(4s3p1d,2s) levels of theory. The geometries are found to differ considerably between the two levels. The vertical and 0−0 excitation spectra were calculated for each isomer. Both singlet and triplet states are described for each, including the lowest lying ππ* excitations and the nOπ* excitations. Remarkably, in the trans spectrum, it is found that the nOπ* state has a higher vertical excitation energy than the lowest ππ* (5.12 v…

Atomic electron transitionChemistryExcited stateExcitation spectraCis-Urocanic AcidSinglet statePhysical and Theoretical ChemistryPerturbation theoryAtomic physicsExcitationSpectral lineThe Journal of Physical Chemistry A
researchProduct

Un retablo mariano de Vicente Carducho reconstruido

1994

AtribuciónUNESCO::HISTORIA::Historia por especialidades::Historia del arteEscuela madrileñaRetablos:HISTORIA::Historia por especialidades::Historia del arte [UNESCO]Pintura barroca
researchProduct

Transmural myocardial ischaemia complicating recovery after dobutamine-atropine stress echocardiography in patients with non-significant coronary art…

2011

In the proposed selection of cases, traditional imaging is integrated with contemporary diagnostic tools available in the cath-lab to navigate the potential mechanisms underlying a very rare complication occurring in the recovery phase of dobutamine-atropine stress echocardiography. The data, collected in a time frame of nearly 15 years, provide interesting elements to possibly evolve from speculative considerations to plausible confirmation of the candidate pathophysiological mechanism mediating the occurrence of transmural myocardial ischaemia after beta-blockers administration.

AtropineMaleChest Painmedicine.medical_specialtyMyocardial ischaemiamedicine.drug_classAdrenergic beta-AntagonistsMyocardial IschemiaCoronary Artery DiseaseCoronary AngiographyCoronary artery diseaseElectrocardiographyInternal medicineStress EchocardiographyHumansMedicineRadiology Nuclear Medicine and imagingBeta blockerAgedbusiness.industryParasympatholyticsGeneral MedicineMiddle Agedmedicine.diseaseFractional Flow Reserve MyocardialAtropineCardiologyFemaleDobutamineCardiology and Cardiovascular MedicinebusinessComplicationCoronary physiologyEchocardiography Stressmedicine.drugEuropean Journal of Echocardiography
researchProduct

Relationships between the social communication questionnaire and pragmatic language, socialization skills, and behavioral problems in children with a…

2019

The Social Communication Questionnaire (SCQ) is one of the most widely used screening instruments for autism spectrum disorder (ASD). This study examined the relationships between the reciprocal social interaction, communication, and repetitive/stereotyped factors on the Strength and Difficulties Questionnaire (SDQ) and pragmatic, socialization, and behavioral problems in children with ASD and children with typical development (TD). Participants were seven- to 11-year-old children with ASD without intellectual disability (

Autism Spectrum Disorderbehavioral disciplines and activitiesDevelopmental psychologySocial Skills03 medical and health sciences0302 clinical medicineSocial skillsSurveys and Questionnairesmental disordersAdaptation PsychologicalDevelopmental and Educational PsychologymedicineHumansMass Screening0501 psychology and cognitive sciencesChildSocial BehaviorProblem BehaviorSocial communicationCommunication05 social sciencesSocializationmedicine.diseaseNeuropsychology and Physiological PsychologyAutism spectrum disorderCase-Control StudiesAutismStereotyped BehaviorPsychology030217 neurology & neurosurgeryReciprocal050104 developmental & child psychologyApplied neuropsychology. Child
researchProduct

Detection of the synthetic drug 4-fluoroamphetamine (4-FA) in serum and urine.

2010

Abstract 4-Fluoroamphetamine (4-FA) was detected in the blood and urine of two individuals suspected for driving under the influence (DUI). The test for amphetamines in urine subjected to immunoassay screening using the CEDIA DAU assay proved positive. Further investigations revealed a 4-FA cross-reactivity of about 6% in the CEDIA amphetamine assay. 4-FA was qualitatively detected in a general unknown screening for drugs using GC/MS in full scan mode. No other drugs or fluorinated phenethylamines were detected. A validated GC/MS method was established in SIM mode for serum analysis of 4-FA with a limit of detection (LOD) of 1 ng/mL and a lower limit of quantification (LLOQ) of 5 ng/mL. Int…

Automobile DrivingPoison controlPhenethylaminesUrinePharmacologyGas Chromatography-Mass SpectrometryPathology and Forensic MedicineDesigner Drugs4-FluoroamphetamineForensic ToxicologyLimit of DetectionMedicineHumansAmphetamineDriving under the influenceDetection limitFluorocarbonsmedicine.diagnostic_testbusiness.industrycelebritiesAmphetaminescelebrities.reason_for_arrestSubstance Abuse DetectionImmunoassaybusinessLawmedicine.drugForensic science international
researchProduct

The marbled crayfish as a paradigm for saltational speciation by autopolyploidy and parthenogenesis in animals

2015

ABSTRACT The parthenogenetic all-female marbled crayfish is a novel research model and potent invader of freshwater ecosystems. It is a triploid descendant of the sexually reproducing slough crayfish, Procambarus fallax, but its taxonomic status has remained unsettled. By cross-breeding experiments and parentage analysis we show here that marbled crayfish and P. fallax are reproductively separated. Both crayfish copulate readily, suggesting that the reproductive barrier is set at the cytogenetic rather than the behavioural level. Analysis of complete mitochondrial genomes of marbled crayfish from laboratory lineages and wild populations demonstrates genetic identity and indicates a single o…

AutopolyploidyMitochondrial DNAQH301-705.5ScienceMarbled meatmedia_common.quotation_subjectParthenogenesisChromosomal speciationMarbled crayfishZoologyGenomeGeneral Biochemistry Genetics and Molecular BiologyBiology (General)Saltational evolutionShellfishmedia_commonbiologymusculoskeletal neural and ocular physiologyQAquatic animalParthenogenesisbiology.organism_classificationCrayfishFecunditySpeciationnervous systemMicrosatelliteEpigeneticsProcambarus fallaxGeneral Agricultural and Biological SciencesResearch Article
researchProduct

Osteonecrosis in Hodgkin lymphoma treated by BEACOPP

2018

BEACOPPOncologymedicine.medical_specialtyVincristineCyclophosphamidebusiness.industrymedicine.medical_treatmentProcarbazineBleomycin030218 nuclear medicine & medical imaging03 medical and health scienceschemistry.chemical_compound0302 clinical medicinechemistryPrednisone030220 oncology & carcinogenesisInternal medicineInternal MedicinemedicineDoxorubicinbusinessEtoposidemedicine.drugInternal Medicine Journal
researchProduct