Search results for "Roof"

showing 10 items of 303 documents

Association Between Serum Levels of Neurofilament Light Chains and Minimal Hepatic Encephalopathy in Patients With Liver Cirrhosis.

2021

INTRODUCTION: Serum biomarkers for the diagnosis of minimal hepatic encephalopathy (MHE) in patients with liver cirrhosis would be desirable. In this proof-of-concept study, we investigated the association between MHE and serum levels of neurofilament light chains (sNfL) in patients with liver cirrhosis. METHODS: sNfL were studied in patients with liver cirrhosis (with or without MHE) and controls (patients with ischemic stroke, transitory ischemic attack, and healthy individuals). MHE was diagnosed using the Psychometric Hepatic Encephalopathy Score. RESULTS: Patients with MHE showed higher sNfL than patients without MHE and controls. In multivariable analyses, higher sNfL were independent…

Liver CirrhosisMalemedicine.medical_specialtyCirrhosisNeurofilament lightGastroenterologyProof of Concept StudySeverity of Illness IndexSerum biomarkersNeurofilament ProteinsInternal medicineMedicineHumansIn patientHepatic encephalopathyAgedbusiness.industryBrief ReportGastroenterologyArea under the curveMiddle Agedmedicine.diseaseHealthy individualsHepatic EncephalopathyIschemic strokeFemalebusinesshuman activitiesBiomarkersClinical and translational gastroenterology
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Analysis of a Collapsed Long-Span Reinforced Concrete Roof in South Italy: Design Mistakes and Material Degradation

2020

In 2004, during ordinary maintenance work, consisting of waterproofing a building located in the south of Italy, the long-span (14.5 m) in situ RC roof partially collapsed. The building, constructed in 1950, was in service as a cinema until 1967 and then utilized as a school until 1985. Lastly, it was a hotel until 2000. In 2004, when the building was not in service and was undergoing maintenance work, it partially collapsed under dead load. After the collapse, which involved a large portion of the roof, several beams, and two columns, the Italian court nominated an official technical consultant to investigate the direct and related causes of the failure. After the main causes were identifi…

Long spanDesign mistakesWaterproofingBond failureBuilding and ConstructionMaterial degradationReinforced concreteShear failureReinforced concreteSettore ICAR/09 - Tecnica Delle CostruzioniWork (electrical)Material DegradationForensic engineeringBuildingSafety Risk Reliability and QualitySettore ICAR/08 - Scienza Delle CostruzioniRoofGeologyCivil and Structural Engineering
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Empirical measures and Vlasov hierarchies

2013

The present note reviews some aspects of the mean field limit for Vlasov type equations with Lipschitz continuous interaction kernel. We discuss in particular the connection between the approach involving the N-particle empirical measure and the formulation based on the BBGKY hierarchy. This leads to a more direct proof of the quantitative estimates on the propagation of chaos obtained on a more general class of interacting systems in [S.Mischler, C. Mouhot, B. Wennberg, arXiv:1101.4727]. Our main result is a stability estimate on the BBGKY hierarchy uniform in the number of particles, which implies a stability estimate in the sense of the Monge-Kantorovich distance with exponent 1 on the i…

MSC 82C05 (35F25 28A33)[PHYS.MPHY]Physics [physics]/Mathematical Physics [math-ph]FOS: Physical sciences01 natural sciencesVlasov type equation Mean-field limit Empirical measure BBGKY hierarchy Monge-Kantorovich distanceMathematics - Analysis of PDEs[MATH.MATH-MP]Mathematics [math]/Mathematical Physics [math-ph]FOS: Mathematics[MATH.MATH-AP]Mathematics [math]/Analysis of PDEs [math.AP]Applied mathematicsMonge-Kantorovich distanceDirect proof0101 mathematicsEmpirical measureMathematical PhysicsMean field limitMathematicsNumerical AnalysisHierarchy010102 general mathematicsVlasov type equationMathematical Physics (math-ph)Empirical measureBBGKY hierarchyLipschitz continuity010101 applied mathematicsKernel (algebra)Uniqueness theorem for Poisson's equationBBGKY hierarchyModeling and SimulationExponent82C05 (35F25 28A33)Analysis of PDEs (math.AP)Kinetic & Related Models
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A phase 2 randomized, double-blind, placebo-controlled, proof-of-concept study of oral seletalisib in primary Sjögren’s syndrome

2020

Abstract Objectives This phase 2 proof-of-concept study (NCT02610543) assessed efficacy, safety and effects on salivary gland inflammation of seletalisib, a potent and selective PI3Kδ inhibitor, in patients with moderate-to-severe primary Sjögren’s syndrome (PSS). Methods Adults with PSS were randomized 1:1 to seletalisib 45 mg/day or placebo, in addition to current PSS therapy. Primary end points were safety and tolerability and change from baseline in EULAR Sjögren’s Syndrome Disease Activity Index (ESSDAI) score at week 12. Secondary end points included change from baseline at week 12 in EULAR Sjögren’s Syndrome Patient Reported Index (ESSPRI) score and histological features in salivary …

Male0301 basic medicineSalivamedicine.medical_specialtyPyridinesprimary Sjögren’s syndromeAdministration Oralprimary Sjogren's syndromePlaceboProof of Concept StudyGastroenterologySalivary Glandshistologyseletalisib03 medical and health sciences0302 clinical medicineDouble-Blind MethodRheumatologyInternal medicineproof-of-conceptmedicineHumansPharmacology (medical)Adverse effect030203 arthritis & rheumatologySalivary glandbiologySurrogate endpointbusiness.industryMiddle Agedmedicine.diseaseSialadenitisphosphatidylinositol 3-kinase delta (PI3K delta)primary Sjögren's syndrome3. Good healthSjogren's Syndrome030104 developmental biologymedicine.anatomical_structureTolerabilityImmunoglobulin MAntirheumatic Agentsphosphatidylinositol 3-kinase delta (PI3Kδ)Quinolinesbiology.protein[SDV.IMM]Life Sciences [q-bio]/ImmunologyFemalebusiness
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A Nomogram to Characterize the Severity of Detrusor Overactivity during the Ice Water Test: Description of the Method and Proof of Concept

2017

<b><i>Aims:</i></b> To develop a nomogram with severity categories for detrusor overactivity (DO). <b><i>Methods:</i></b> By conducting ice water tests (IWT) in 55 patients with Parkinson’s disease, we identified criteria to describe characteristics of the detrusor pressure curves: (1) a gradient of Δ<i>pdet</i> over Δt at the maximum detrusor pressure and (2) the area under the curve. In a nomogram, 10 severity categories of DO were established: 1 and 2 were assigned to group A (mild), 3 and 4 to group B (moderate) and 5–10 to group C (severe). <b><i>Results:</i></b> In the nomogram, negative IWT (20) appea…

Malemedicine.medical_specialtygenetic structuresUrologyUrinary Bladder030232 urology & nephrologyUrologyurologic and male genital diseasesProof of Concept Study03 medical and health sciences0302 clinical medicinemedicineHumansUrinary Bladder NeurogenicAgedUrinary Bladder Overactivebusiness.industryArea under the curveReproducibility of ResultsParkinson DiseaseMiddle AgedNomogramIce waterNomogramsUrodynamicsAdministration IntravesicalUrinary Incontinence030220 oncology & carcinogenesisDetrusor pressureFemalebusinessUrologia Internationalis
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How does an In-containing underlayer prevent the propagation of defects in InGaN QW LEDs?: identification of SRH centers and modeling of trap profile

2021

Recent reports indicated that the use of an InAlN underlayer (UL) can significantly improve the efficiency of InGaN/GaN quantum well (QW) LEDs. Currently, this result is explained by considering that the UL reduces the density of nonradiative recombination centers in the QWs. However, an experimental proof of the reduction of defects in the QWs is not straightforward. In this paper, we use combined electrical (I-V), optical (L-I), capacitance (C-V), steady-state photocapacitance (SSPC) and light-assisted capacitance-voltage (LCV) measurements to explain why devices with UL have a much higher efficiency than identical LEDs without UL. Specifically, we demonstrated an improvement in both elec…

Materials scienceLEDsbusiness.industryunderlayergrowth of defectsSSPC measurementsLimitingdefects concentration; growth of defects; LEDs; SSPC measurements; underlayerSettore ING-INF/01 - Elettronicadefects concentrationCapacitancelaw.inventionTrap (computing)Experimental prooflawdefects concentration growth of defects LEDs SSPC measurements underlayerOptoelectronicsbusinessQuantum wellRecombinationLight-emitting diodeGallium Nitride Materials and Devices XVI
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Smart optically active VO2 nanostructured layers applied in roof-type ceramic tiles for energy efficiency

2016

Abstract The capability to control in an smart way the infrared reflectance to environmental temperature variations can be achieved with thermochromic materials like VO2. In this paper, we report the application of VO2 on ceramic tiles aiming to control the reflected infrared radiation on smart roofs and thus improving the energy efficiency, which is associated to the reduction of the carbon dioxide emissions. The VO2 nanoparticles have been produced by hydrothermal synthesis assisted by microwave irradiation, providing a new, quicker and cleaner production route. Afterwards, the VO2 nanoparticles were transferred to the surface of ceramic glassy tiles, which were prepared through dispersin…

Materials scienceRenewable Energy Sustainability and the EnvironmentAnnealing (metallurgy)DopingNanoparticlechemistry.chemical_elementNanotechnology02 engineering and technologyTungsten010402 general chemistry021001 nanoscience & nanotechnology01 natural sciences0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic Materialschemistryvisual_artvisual_art.visual_art_mediumHydrothermal synthesisCeramic0210 nano-technologyhuman activitiesRoofEfficient energy useSolar Energy Materials and Solar Cells
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7.22 Health Monitoring of High Performance Composite Pressure Vessels

2018

The most important form of damage in carbon fiber reinforced composite pressure vessels is the failure of the fibers however the rate of fiber failure is controlled by the viscoelastic nature of the matrix, which determines overall in-service lifetimes. This type of damage is very different from that encountered with metal pressure vessels and requires a detailed understanding in order to ensure reliability. Innovative proof testing methods based on these processes are necessary. The damage processes and the means of quantifying them are discussed. Their reliability under pressure over periods of decades is analyzed. Intrinsic safety factors linked directly to the properties of the composit…

Materials sciencebusiness.industry020502 materialsCarbon fiber reinforced compositeComposite number02 engineering and technologyStructural engineering021001 nanoscience & nanotechnologyPressure vesselViscoelasticityIntrinsic safety0205 materials engineeringFiberProof test0210 nano-technologybusinessReliability (statistics)
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Transillumination imaging through biological tissue by single-pixel detection

2015

One challenge that has long held the attention of scientists is that of clearly seeing objects hidden by turbid media, as smoke, fog or biological tissue, which has major implications in fields such as remote sensing or early diagnosis of diseases. Here, we combine structured incoherent illumination and bucket detection for imaging an absorbing object completely embedded in a scattering medium. A sequence of low-intensity microstructured light patterns is launched onto the object, whose image is accurately reconstructed through the light fluctuations measured by a single-pixel detector. Our technique is noninvasive, does not require coherent sources, raster scanning nor time-gated detection…

Materials sciencebusiness.industryDetectorHolographyTransilluminationIterative reconstructionSample (graphics)law.inventionOpticsCompressed sensinglawProof of conceptComputer visionArtificial intelligenceRaster scanbusinessSPIE Proceedings
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Note: Simultaneous modulation transfer spectroscopy on transitions of multiple atomic species for compact laser frequency reference modules

2018

We present a technique for simultaneous laser frequency stabilization on transitions of multiple atomic species with a single optical setup. The method is based on modulation transfer spectroscopy, and the signals are separated by modulating at different frequencies and electronically filtered. As a proof of concept, we demonstrate simultaneous spectroscopy of the potassium D1, D2 and rubidium D2 transitions. The technique can be extended in principle to other atomic species given the availability of optics and cells and allows the development of versatile and compact frequency reference modules.

Materials sciencebusiness.industrychemistry.chemical_elementAtomic species01 natural sciencesRubidium010309 opticsModulation transferchemistryProof of concept0103 physical sciencesOptoelectronicsPhysics::Atomic PhysicsLaser frequency010306 general physicsbusinessSpectroscopyInstrumentationReview of Scientific Instruments
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