Search results for "Rupture"
showing 10 items of 203 documents
The Relationship Between Aortic Root Size and Hypertension: An Unsolved Conundrum
2017
Thoracic aortic aneurysms rupture and dissection are among the most devastating vascular diseases, being characterized by elevated mortality, despite improvements in diagnostic imaging and surgical techniques. An increased aortic root diameter (ARD) represents the main risk factor for thoracic aortic dissection and rupture and for aortic valve regurgitation. Even though arterial hypertension is commonly regarded as a predisposing condition for the development of thoracic aorta aneurysms, the role of blood pressure (BP) as determinant of aortic root enlargement is still controversial. The use of different methods for indexation of ARD may have in part contributed to the heterogeneous finding…
Mortality of ruptured abdominal aortic aneurysm with selective use of endovascular repair
2009
The aim of this review was to examine the results over a seven-year period of treatment for ruptured abdominal aortic aneurysm (RAAA). From 2002 on, our tertiary referral centre offered both open and endovascular (EVAR) treatment modalities for RAAA. All patients with a proven RAAA who were admitted into our hospital were included. Primary outcome measure was surgical mortality. In total 261 patients were admitted with suspicion of acute AAA. Of these, 175 (67%) had a RAAA, confirmed by computed tomography-scanning or at laparotomy. One hundred and fifty-nine patients (90.9%) were treated, 114 by open repair and 45 by EVAR. Overall mortality of patients treated was 25.2%, with an open repai…
Le contentieux de la rupture abusive de relations d'affaires établies entre dans le champ d'application de la clause compromissoire stipulée dans le …
2012
International audience; (Civ. 1re, 8 juillet 2010, n° 09-67.013, D. 2010. 2884, obs. X. Delpech, note M. Audit et O. Cuperlier ; ibid. 2540, obs. Centre de droit de la concurrence Yves Serra ; ibid. 2933, obs. T. Clay ; Rev. crit. DIP 2010. 743, note D. Bureau et H. Muir Watt ; cette Revue 2011. 667, obs. P. Delebecque ; Rev. arb. 2010. 513, note R. Dupeyré)
Que reste-t-il de l'abus dans le non-renouvellement du contrat ?
2014
International audience
1267 HSP70-2 polymorphism as a risk factor for carotid plaque rupture and cerebral ischaemia in old type 2 diabetes-atherosclerotic patients.
2005
Patients with type 2 diabetes mellitus (NIDDM) are at risk for macrovascular disease complications, such as myocardial infarction (MI) or stroke from plaque rupture. Cytokines play a key role in plaque vulnerability. IFN-gamma inhibits collagen synthesis thereby affecting plaque stability. High IL-6, TNF-alpha, and dyslipidemia are risk factors for thrombosis. Abnormal increments of HSP70 in atherosclerotic plaques might lead to plaque instability and rupture caused by chronic inflammation, which up-regulates the expression of pro-inflammatory cytokines (IL-6 and TNF-alpha) in human monocytes. Studies of a polymorphic PstI site lying in the coding region at position 1267 of the HSP70-2 gene…
Évolution des températures observées en Bourgogne (1961-2011)
2014
International audience; Depuis un demi-siècle environ, l’augmentation des concentrations atmosphériques en gaz à effet de serre a entraîné une élévation de température qui peut être analysée selon des échelles emboîtées, allant de la planète aux territoires. Dans cette étude, les mesures effectuées sur le réseau de stations Météo-France sont mobilisées pour analyser la température en Bourgogne sur la période 1961-2011. Le réchauffement observé a des caractéristiques très proches des moyennes françaises. Il est plus fort que sur la moyenne planétaire. Il est marqué par une rupture nette délimitant deux périodes bien différentes : 1961-1987 et 1988-2011. Une interpolation par régression krige…
Technition: When Tools Come Out of the Closet
2020
People are ambivalently enthusiastic and anxious about how far technology can go. Therefore, understanding the neurocognitive bases of the human technical mind should be a major topic of the cognitive sciences. Surprisingly, however, scientists are not interested in this topic or address it only marginally in other mainstream domains (e.g., motor control, action observation, social cognition). In fact, this lack of interest may hinder our understanding of the necessary neurocognitive skills underlying our appetence for transforming our physical environment. Here, we develop the thesis that our technical mind originates in perhaps uniquely human neurocognitive skills, namely, technical-reas…
Effet de l'orientation des fibres des plis adjacents sur la résistance au délaminage en mode I pur = Effect of the fibre's orientation of adjacent pl…
2009
National audience; Ce travail concerne l'étude de l'effet de l'orientation des fibres des plis adjacents à la fissure dans une éprouvette DCB (Double Cantilever Beam) sur la résistance au délaminage en mode I pur. Afin d'isoler l'influence de l'orientation l'étude porte sur des stratifiés particuliers ayant tous les mêmes matrices de comportement global A B D. Les résultats expérimentaux montrent une grande variation de résistance au délaminage GIC et des courbes R selon l'orientation des plis situés de part et d'autre du plan de fissure. Une modélisation par éléments finis permet de mettre en évidence l'importance de l'état de contraintes locales et donc de l'endommagement au voisinage du …
Imaging techniques for the vulnerable coronary plaque
2007
The goal of this article is to illustrate the main invasive and noninvasive diagnostic modalities to image the vulnerable coronary plaque, which is responsible for acute coronary syndrome. The main epidemiologic and histological issues are briefly discussed in order to provide an adequate background. Comprehensive coronary atherosclerosis imaging should involve visualization of the entire coronary artery tree and plaque characterization, including three-dimensional morphology, relationship with the lumen, composition, vascular remodelling and presence of inflammation. No single technique provides such a comprehensive description, and no available modality extensively identifies the vulnerab…
Lymphatic vessels are present in human saccular intracranial aneurysms
2022
AbstractSaccular intracranial aneurysm (sIA) rupture leads to subarachnoid haemorrhage and is preceded by chronic inflammation and atherosclerotic changes of the sIA wall. Increased lymphangiogenesis has been detected in atherosclerotic extracranial arteries and in abdominal aortic aneurysms, but the presence of lymphatic vessels in sIAs has remained unexplored. Here we studied the presence of lymphatic vessels in 36 intraoperatively resected sIAs (16 unruptured and 20 ruptured), using immunohistochemical and immunofluorescence stainings for lymphatic endothelial cell (LEC) markers. Of these LEC-markers, both extracellular and intracellular LYVE-1-, podoplanin-, VEGFR-3-, and Prox1-positive…