Search results for "Ruthenium"

showing 10 items of 393 documents

BODIPY-phosphane as a versatile tool for easy access to new metal-based theranostics

2012

A new BODIPY-phosphane was synthesized and proved to be a versatile tool for imaging organometallic complexes. It also led to easy access to a new family of theranostics, featuring gold, ruthenium and osmium complexes. The compounds' cytotoxicity was tested on cancer cells, and their cell uptake was followed by fluorescence microscopy in vitro.

Boron Compoundsinorganic chemicalsCell SurvivalPhosphinesINHIBITIONchemistry.chemical_elementGOLD COMPOUNDSRutheniumInorganic ChemistryMetalchemistry.chemical_compoundGold CompoundsPOLYPYRIDINE COMPLEXESCoordination ComplexesCHEMISTRYCell Line TumorFluorescence microscopeHumansOrganic chemistryOsmiumCytotoxicityAGENTSMicroscopy ConfocalChemistryOsmiumCombinatorial chemistryRutheniumMetalsvisual_artPHOTOPHYSICAL PROPERTIESCancer cellvisual_art.visual_art_mediumMODESGoldBODIPYDYESBEHAVIOR
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Cobalt Electrolyte/Dye Interactions in Dye-Sensitized Solar Cells: A Combined Computational and Experimental Study

2012

We report a combined experimental and computational investigation to understand the nature of the interactions between cobalt redox mediators and TiO2 surfaces sensitized by :ruthenium and organic dyes, and their impact on. the performance of the corresponding dye-sensitized solar cells (DSSCs). We : focus: on different ruthenium dyes and fully organic dyes, to understand the dramatic loss of efficiency observed for the prototype Ru(II) N719 dye in conjunction with :Cobalt: electrolytes. Both N719- and Z907-based DSSCs showed an increased lifetime in iodine-based electrolyte compared to the cobalt-based redox-shuttle; While the organic D21L6 and D25L6 cycles endowed.With long alkoxy chains,…

COLLOIDAL TIO2 FILMSinorganic chemicalsLOW QUANTUM YIELDSInorganic chemistrychemistry.chemical_element02 engineering and technologyElectrolyte010402 general chemistryPhotochemistry01 natural sciencesBiochemistryRedoxREDOX COUPLECatalysisEFFECTIVE CORE POTENTIALSDENSITY-FUNCTIONAL THEORYColloid and Surface ChemistryDENSITY-FUNCTIONAL THEORY; EFFECTIVE CORE POTENTIALS; INTRAMOLECULAR ELECTRON-TRANSFER; TRANSITION-METAL-COMPLEXES; COLLOIDAL TIO2 FILMS; LOW QUANTUM YIELDS; MOLECULAR CALCULATIONS; REDOX COUPLE; MAGNETIC-PROPERTIES; PHOTOVOLTAIC CELLSMAGNETIC-PROPERTIESPHOTOVOLTAIC CELLSLigandGeneral Chemistry021001 nanoscience & nanotechnologyMOLECULAR CALCULATIONSTRANSITION-METAL-COMPLEXES0104 chemical sciencesMarcus theoryRutheniumDye-sensitized solar cellchemistryAlkoxy groupINTRAMOLECULAR ELECTRON-TRANSFER0210 nano-technologyCobalt
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Red and blue luminescent metallo-supramolecular coordination polymers assembled through π–π interactions †

2000

The use of π-stacking interactions to control the aggregation of photo-active metal centres is explored through the design of bis(2,2′;6′,2′′-terpyridyl) metal complexes functionalised with biphenyl ‘tails’. Aryl–aryl interactions control the aggregation of the metal complexes into polymetallic arrays in the solid state. Cobalt(II), ruthenium(II), nickel(II), copper(II), zinc(II) and cadmium(II) bis-ligand complexes and a mixed ligand ruthenium(II) complex have been structurally characterised. The solid-state structures are dependent on which units dominate the π-stacking. For cobalt, ruthenium, nickel and copper, biphenylene–biphenylene interactions lead to linear rod-like arrays, while fo…

CadmiumSupramolecular chemistrychemistry.chemical_elementGeneral ChemistryZincBiphenylenePhotochemistryCopperRutheniumNickelchemistry.chemical_compoundchemistryPolymer chemistryCobaltJournal of the Chemical Society, Dalton Transactions
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The CO-releasing molecule CORM-3 protects against articular degradation in the K/BxN serum transfer arthritis model.

2010

Contains fulltext : 89015.pdf (Publisher’s version ) (Closed access) Carbon monoxide-releasing molecules can counteract inflammatory responses. The aim of this study was to investigate whether tricarbonylchloro(glycinate)ruthenium (II) (CORM-3) is able to control the effector phase of experimental arthritis. Arthritis was induced in C57Black-6 mice by an intraperitoneal injection of serum from arthritic K/BxN mice. CORM-3 was administered intraperitoneally at 10 mg/kg/day (5 mg/kg twice a day) from days 0 to 10 and animals were sacrificed on day 11. Serum levels of osteocalcin and prostanoids were measured by enzyme-linked immunosorbent assay and radioimmunoassay. Gene expression was determ…

Cartilage ArticularMaleSerummedicine.medical_specialtymedicine.medical_treatmentIntraperitoneal injectionArthritisMice TransgenicHMGB1Auto-immunity transplantation and immunotherapy [N4i 4]RutheniumMicechemistry.chemical_compoundMice Inbred NODInternal medicineOrganometallic CompoundsmedicineAnimalsPharmacologyCarbon MonoxidebiologyChemistryProstaglandin D2 synthaseRadioimmunoassaymedicine.diseaseArthritis ExperimentalMice Inbred C57BLDisease Models AnimalEndocrinologyRANKLbiology.proteinOsteocalcinProstaglandin D2Infection and autoimmunity [NCMLS 1]European Journal of Pharmacology
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Photoactivation of Anticancer Ru Complexes in Deep Tissue: How Deep Can We Go?

2017

Activation of anticancer therapeutics such as ruthenium (Ru) complexes is currently a topic of intense investigation. The success of phototherapy relies on photoactivation of therapeutics after the light passes through skin and tissue. In this paper, the photoactivation of anticancer Ru complexes with 671-nm red light through tissue of different thicknesses was studied. Four photoactivatable Ru complexes with different absorption wavelengths were synthesized. Two of them (Ru3 and Ru4) were responsive to wavelengths in the “therapeutic window” (650–900 nm) and could be activated using 671-nm red light after passing through tissue up to 16-mm-thick. The other two (Ru1 and Ru2) could not be ac…

Cell SurvivalInfrared Rayschemistry.chemical_elementAntineoplastic Agents02 engineering and technologyAbsorption (skin)010402 general chemistryPhotochemistry01 natural sciencesCatalysisRutheniumMETALLODRUGDeep tissueCoordination ComplexesHumansRed lightPHOTOTHERAPYTherapeutic windowChemistryPHOTOCHEMISTRYOtras Ciencias QuímicasOrganic ChemistryLight activatedCiencias QuímicasGeneral Chemistry021001 nanoscience & nanotechnology0104 chemical sciencesRutheniumRU COMPLEXSpectrophotometryCancer cellANTICANCER0210 nano-technologyCIENCIAS NATURALES Y EXACTASHeLa Cells
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Design of enzyme-mediated controlled release systems based on silica mesoporous supports capped with ester-glycol groups

2012

[EN] An ethylene glycol-capped hybrid material for the controlled release of molecules in the presence of esterase enzyme has been prepared. The final organic-inorganic hybrid solid S1 was synthesized by a two-step procedure. In the first step, the pores of an inorganic MCM-41 support (in the form of nanoparticles) were loaded with [Ru(bipy) 3]Cl 2 complex, and then, in the second step, the pore outlets were functionalized with ester glycol moieties that acted as molecular caps. In the absence of an enzyme, release of the complex from aqueous suspensions of S1 at pH 8.0 is inhibited due to the steric hindrance imposed by the bulky ester glycol moieties. Upon addition of esterase enzyme, del…

Cell viabilityINGENIERIA DE LA CONSTRUCCIONEthyleneRuthenium complexesMCM-41 supportsCytotoxicityGlycol derivativesEsteraseFunctionalizedOrganic-inorganic hybrid solidsGlycolschemistry.chemical_compoundQUIMICA ORGANICATumor Cells CulturedElectrochemistryControlled release systemsOrganic chemistryControlled releaseGeneral Materials ScienceSteric hindrancesMCF-7 cellsSpectroscopyHydrolysisEsterasesSilicaEstersSurfaces and InterfacesSilicon DioxideCondensed Matter PhysicsControlled releaseChlorine compoundsEster bondsBody fluidsHybrid materialsHybrid materialPorosityCell deathCell SurvivalSurface PropertiesCytotoxic drugsRutheniumHydrolysisEnzymatic hydrolysisEsterase enzymesPolymer chemistryHumansCamptothecin (CPT)Molecular capSize reductionsTherapeutic ApplicationEthylene glycolTwo-step procedureEsterificationSuspensions (fluids)Ruthenium compoundsQUIMICA INORGANICAMesoporous supportOligo(ethylene glycol)Cell internalizationMolecular gatesConfocal microscopychemistryEnzymatic hydrolysisEnzyme-mediated hydrolysisNanoparticlesCamptothecinCell cultureMesoporous materialAqueous suspensionsEthylene glycolHeLa Cells
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cis-Aquabis[bis(diphenylphosphino)ethane-κ2 P,P′]chlororuthenium(II) hexafluorophosphate dichloromethane sesquisolvate hemihydrate

2006

In the title compound, [RuCl(C26H24P)2(H2O)]PF6·1.5CH2Cl2·0.5H2O, the complex RuII cation is in a slightly distorted octahedral environment, chelated by two bis(diphenylphosphino)ethane ligands, with a water molecule and a chloride anion in a mutually cis geometry completing the coordination.

ChemistryHemihydratechemistry.chemical_elementGeneral ChemistryCondensed Matter PhysicsHEXAPhosphateMedicinal chemistryChlorideMethaneRutheniumchemistry.chemical_compoundmedicineOrganic chemistryGeneral Materials ScienceChelationmedicine.drugActa Crystallographica Section E Structure Reports Online
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Trans-dicyanobis(acetylacetonato)ruthenate(III) as a precursor to build novel cyanide-bridged RuIII–MII bimetallic compounds [M=Co and Ni]

2006

Abstract The use of the mononuclear complex trans-[Ru(acac)2(CN)2]− as a ligand towards the preformed species [Ni2L(H2O)2Cl2], [Co(dmphen)](NO3)2, [Ni(dmphen)](NO3)2 and [Co(H2O)6](NO3)2 afforded the novel cyanide-bridged bimetallic compounds of formula [{Ru(acac)2(CN)2}{Ni2(L)(H2O)2}]{Ru(acac)2(CN)2}·2H2O (1), [{Ru(acac)2(CN)2}{Co(dmphen)(NO3)}]·H2O (2) and [{Ru(acac)2(CN)2}{Ni(dmphen)(NO3)}]·H2O (3) and [{Ru(acac)2(CN)2}2Co] (4) [Hacac = acetylacetone, dmphen = 2,9-dimethylphenanthroline and H2L = 11,23-dimethyl-3,7,15,19-tetrazatricyclo[19.3.1.19,13]hexacosa-2,7,9,11,13(26),14,19,21(25),22,24-decaene-25,26-diol]. Their syntheses, X-ray crystal structures and magnetic properties are repor…

ChemistryInorganic chemistrychemistry.chemical_elementCrystal structureRutheniumInorganic ChemistryCrystallographyNickelOctahedronMaterials ChemistryAntiferromagnetismPhysical and Theoretical ChemistryIsostructuralCobaltBimetallic stripCoordination Chemistry Reviews
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Synthesis, reactivity and structures of ruthenium carbonyl clusters with telluride and hydride ligands

2002

The reaction of [Cp* 2 Nb(Te 2 H)] ( 1 ) (Cp*=C 5 Me 5 ) with [Ru 3 (CO) 12 ] in boiling toluene gave [Ru 3 (μ 2 -H) 2 (CO) 9 (μ 3 -Te)] ( 2 ), [Ru 6 (μ 3 -H)(CO) 15 (μ 3 -Te) 3 ][Cp* 2 Nb(CO) 2 ] ( 3 ) and [Ru 5 (μ 2 -H)(CO) 14 (μ 4 -Te)][Cp* 2 Nb(CO) 2 ] ( 4 ) along with already known [Ru 4 (CO) 11 (μ 4 -Te) 2 ] ( 5 ). Complexes 2 – 4 were analytically and spectroscopically characterized and X-ray diffraction analyses of 3 and 4 were carried out. The anion of 3 is built up of a triangular hexametallic core of C 3 v symmetry, in which the central Ru 3 triangle, being bridged by a μ 3 -H ligand, is composed of three corner-linked Ru 3 Te tetrahedra. The main structural feature of the anion …

ChemistryLigandOrganic ChemistryCluster chemistrychemistry.chemical_elementCrystal structureBiochemistrySquare pyramidal molecular geometryRutheniumInorganic ChemistryCrystallographychemistry.chemical_compoundOctahedronTellurideMaterials ChemistryReactivity (chemistry)Physical and Theoretical ChemistryJournal of Organometallic Chemistry
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Syntheses and characterization of novel ruthenium complexes based on 1,3-dicyanobenzene

2007

Submitted by António Freitas (amsf@uma.pt) on 2019-06-14T13:25:52Z No. of bitstreams: 1 Syntheses and Characterization of Novel Ruthenium Complexes Based on 13-DicyanobenzeneJoãoRodrigues.pdf: 354444 bytes, checksum: edc8aaaa84900d75321648e76e0c8e27 (MD5) Made available in DSpace on 2019-06-14T13:25:52Z (GMT). No. of bitstreams: 1 Syntheses and Characterization of Novel Ruthenium Complexes Based on 13-DicyanobenzeneJoãoRodrigues.pdf: 354444 bytes, checksum: edc8aaaa84900d75321648e76e0c8e27 (MD5) Previous issue date: 2007 info:eu-repo/semantics/publishedVersion

ChemistryLigandOrganic Chemistrychemistry.chemical_elementCrystal structure.BiochemistryRutheniumCharacterization (materials science)RutheniumInorganic ChemistryFaculdade de Ciências Exatas e da EngenhariaCrystallographyLigand substitutionHomobimetallicMaterials ChemistryHeterobimetallicBuilding blockPhysical and Theoretical ChemistryNitrileJournal of Organometallic Chemistry
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