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showing 10 items of 706 documents

Clinical Benefits of Early Triptan Therapy for Migraine

2004

The introduction of the triptans brought advances in achieving complete and sustained pain resolution in migraine patients, compared with non-migraine-specific treatments. However, sustained pain-free rates for triptans recorded in many clinical trials are still relatively low. This may be due to study participants being treated late into the attack, when pain is already moderate or severe. Studies with almotriptan have shown that efficacy is enhanced when treatment is given early in a migraine attack while pain is still mild, compared with later administration when pain intensity is greater. Developments in our understanding of migraine pathophysiology provide a rationale for this phenome…

medicine.medical_specialtyIndolesCentral sensitizationMigraine DisordersTriptans03 medical and health sciences0302 clinical medicinePatient satisfactionIntervention (counseling)AlmotriptanSecondary PreventionmedicineHumans030212 general & internal medicinePractice Patterns Physicians'Intensive care medicineAnalgesicsClinical Trials as TopicEvidence-Based Medicinebusiness.industryDisease progressionGeneral Medicinemedicine.diseaseTryptaminesSerotonin Receptor AgonistsClinical trialTreatment OutcomeMigrainePatient SatisfactionAcute DiseaseDisease ProgressionPhysical therapyNeurology (clinical)businessAttitude to Health030217 neurology & neurosurgerymedicine.drugCephalalgia
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Bilateral Ultrathin Descemet’s Stripping Automated Endothelial Keratoplasty vs. Bilateral Penetrating Keratoplasty in Fuchs’ Dystrophy: Corneal Highe…

2021

Background and Objectives: The objective of this paper is to compare the visual outcomes and quality of life (QoL) after bilateral ultrathin Descemet’s stripping automated endothelial keratoplasty (UT-DSAEK) with bilateral penetrating keratoplasty (PK) for Fuchs’ endothelial dystrophy (FED). Materials and Methods: Retrospective comparative cohort study, including 11 patients with FED who underwent bilateral PK and 13 patients with FED who underwent bilateral UT-DSAEK. All patients were already pseudophakic or had undergone a combined cataract procedure. The main outcomes were corrected distance visual acuity (CDVA) corneal higher-order aberrations (HOAs), contrast sensitivity (CS) and quali…

medicine.medical_specialtyMedicine (General)Visual acuityDistance visual acuitygenetic structuresvisual acuitymedia_common.quotation_subjectmedicine.medical_treatmentFuchs' dystrophyArticleCohort StudiesR5-920Quality of lifeOphthalmologyhigher-order aberrationmedicineContrast (vision)HumansEye surgerymedia_commonRetrospective Studiescontrast sensitivityhigher-order aberrationsbusiness.industryFuchs' Endothelial DystrophyDystrophybilateral penetrating keratoplastyGeneral Medicinemedicine.diseasebilateral ultrathin DSAEKeye diseasesAberrations of the eyebilateral ultrathin DSAEK; bilateral penetrating keratoplasty; visual acuity; contrast sensitivity; higher-order aberrations; quality of lifequality of lifevisual acuity.medicine.symptombusinessDescemet Stripping Endothelial KeratoplastyKeratoplasty PenetratingMedicina
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The 2016 European Thyroid Association/European Group on Graves' Orbitopathy Guidelines for the Management of Graves' Orbitopathy

2015

Graves' orbitopathy (GO) is the main extrathyroidal manifestation of Graves' disease, though severe forms are rare. Management of GO is often suboptimal, largely because available treatments do not target pathogenic mech anisms of the disease. Treatment should rely on a thorough assessment of the activity and severity of GO and its impact on the patient's quality of life. Local measures (artificial tears, ointments and dark glasses) and control of risk factors for progression (smoking and thyroid dysfunction) are recommended for all patients. In mild GO, a watchful strategy is usually sufficient, but a 6-month course of selenium supplementation is effective in improving mild manifestations …

medicine.medical_specialtyPediatricsCyclosporine; Eyelid surgery; Glucocorticoids; Graves' orbitopathy; Orbital decompression; Orbital radiotherapy; Rituximab; Selenium; Squint surgeryEndocrinology Diabetes and Metabolismmedicine.medical_treatmentMedizin030209 endocrinology & metabolismDiseaseGuidelines03 medical and health sciencesGraves' orbitopathySeleniumEndocrinology0302 clinical medicineQuality of lifemedicineEyelid surgeryOrbital radiotherapyGlucocorticoidsbusiness.industryCumulative doseThyroideye diseasesSurgeryDiabetes and MetabolismOrbital decompressionArtificial tearsmedicine.anatomical_structureMethylprednisolone030221 ophthalmology & optometryCyclosporineRituximabSquint surgerybusinessRituximabWatchful waitingCyclosporine; Eyelid surgery; Glucocorticoids; Graves' orbitopathy; Orbital decompression; Orbital radiotherapy; Rituximab; Selenium; Squint surgery; Endocrinology Diabetes and Metabolismmedicine.drug
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A survey on current practice in the neurosurgical management of preterm infants with posthemorrhagic hydrocephalus in Germany.

2012

Background and Study Aims  Different approaches to the management of preterm infants with posthemorrhagic hydrocephalus (PHH) are described in the literature. Likewise, neurosurgical and pediatric surgical departments in German hospitals use different methods to treat these patients. The aim of this study was therefore to assess the current situation regarding the management of PHH, which is a first and essential step toward the development of standards of practice. Patients and Methods  In the second half of 2009, we sent standardized questionnaires to 139 neurosurgical departments (number of returned questionnaires: 98) and 73 pediatric surgical departments (returned questionnaires: 62) t…

medicine.medical_specialtyPediatricsNeurosurgeryPediatricsVentriculoperitoneal ShuntNeurosurgical ProceduresVentriculoperitoneal shuntsPosthemorrhagic hydrocephalusGermanySurveys and QuestionnairesPediatric surgeryMedicineInitial treatmentHumansPractice Patterns Physicians'Csf shuntbusiness.industryData CollectionInfant Newbornmedicine.diseasehumanitiesIntraventricular hemorrhageCurrent practicePractice Guidelines as TopicSurgeryNeurology (clinical)NeurosurgerybusinessIntracranial HemorrhagesInfant PrematureHydrocephalusJournal of neurological surgery. Part A, Central European neurosurgery
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Graves Disease With Thyroid-Stimulating Hormone Receptor–Blocking Autoantibodies During Pregnancy

2020

medicine.medical_specialtyPregnancybiologyBlocking (radio)business.industryGraves' diseaseThyroidAutoantibodyGeneral Medicinemedicine.diseasemedicine.anatomical_structureEndocrinologyThyroid-stimulating hormonePlacentaInternal medicineInternal Medicinebiology.proteinmedicineAntibodybusinessAnnals of Internal Medicine
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Adult Coats’ Disease Successfully Managed with the Dexamethasone Intravitreal Implant (Ozurdex®) Combined with Retinal Photocoagulation

2012

Purpose: To report a case of Coats’ disease managed with the dexamethasone intravitreal implant Ozurdex® (Allergan, Inc., Irvine, Calif., USA) combined with retinal photocoagulation. Methods: A 46-year-old female with 20/200 visual acuity was diagnosed with Coats’ disease with secondary retinal vasoproliferative tumor. An initial approach was performed with an intravitreal injection of the sustained-release dexamethasone implant Ozurdex. After reattachment of the retina, the telangiectatic vessels were treated with laser photocoagulation. Results: The patient’s visual acuity improved to 20/25 after the intravitreal Ozurdex. No further recurrences of exudation were evident through the 12-mon…

medicine.medical_specialtyRetinal vasoproliferative tumorVisual acuitychemistry.chemical_compoundRetinal telangiectasislcsh:OphthalmologyOphthalmologymedicineDexamethasone Intravitreal ImplantDexamethasone intravitreal implant (Ozurdex®)Coats' diseaseCoats’ diseaseDexamethasoneRetinabusiness.industryRetinalmedicine.diseaseSurgeryOphthalmologymedicine.anatomical_structurechemistrylcsh:RE1-994Published: March 2012Retinal TelangiectasisImplantmedicine.symptombusinessmedicine.drugCase Reports in Ophthalmology
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An uncommon clinical picture: Wellens’ syndrome in a morbidly obese young man

2010

A 39-year-old man presented to the emergency department (ED) of the ‘‘Paolo Giaccone’’ Academic Hospital, Palermo (Italy). He had anterior chest pain that did not radiate to the neck or arms. The patient came from home where the chest pain initiated. The patient was morbidly obese (BMI 54 kg/m). At the ED, the patient’s blood pressure was 120/80 mmHg, the serum troponin I concentration was 0.029 ng/ml (normal values \ 0.034, borderline 0.034–0.12), myoglobin 45 ng/ml (normal values \ 120). While experiencing chest pain, the patient underwent a standard 12 lead electrocardiogram (ECG) that was normal. An echocardiogram, also during the chest pain, excluded the presence of hypo-akinetic left …

medicine.medical_specialtySettore MED/09 - Medicina InternaUnstable anginabusiness.industryWellens' SyndromeWellens' syndromemedicine.diseaseChest painacute coronary syndrome; Wellens' SyndromeSettore MED/45 - Scienze Infermieristiche Generali Cliniche E PediatricheSettore MED/11 - Malattie Dell'Apparato Cardiovascolareacute coronary syndromeStenosisEndocrinologyAnterior chestInternal medicineT waveEmergency MedicineInternal MedicinemedicineCardiologyST segmentMyocardial infarctionmedicine.symptombusinessInternal and Emergency Medicine
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Survey of root canal irrigating solutions used in dental practices within Germany.

2014

Aim Irrigant usage information in relation to years of professional experience was collected from general dentists in different German federal states by means of a questionnaire. Methodology A short survey concerning endodontic treatment and use of irrigants was mailed to 4240 dentists or delivered to 3720 dental offices as an extra page in a journal in eight German states. Detailed information concerning the most frequently used irrigants, their concentrations, the spectrum of disinfectants used in root canal treatment concepts for vital and nonvital pulps, main topics of continuing education as well as years of professional experience was collected. The statistical analysis of differences…

medicine.medical_specialtySodium HypochloriteRoot canalDentistryGermanGermanySurveys and QuestionnairesmedicineHumansStatistical analysisGeneral DentistryPractice Patterns Dentists'Response rate (survey)Root Canal Irrigantsbusiness.industryHydrogen Peroxidelanguage.human_languageTest (assessment)medicine.anatomical_structureDental OfficesFamily medicinelanguageGeneral Practice DentalIRRIGATING SOLUTIONSbusinessRoot Canal PreparationFederal stateDisinfectantsInternational endodontic journal
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Infrared thermal imaging in the diagnosis of musculoskeletal injuries: a systematic review and meta-analysis.

2014

OBJECTIVE. Musculoskeletal injuries occur frequently. Diagnostic tests using ionizing radiation can lead to problems for patients, and infrared thermal imaging could be useful when diagnosing these injuries. CONCLUSION. A systematic review was performed to determine the diagnostic accuracy of infrared thermal imaging in patients with musculoskeletal injuries. A meta-analysis of three studies evaluating stress fractures was performed and found a lack of support for the usefulness of infrared thermal imaging in musculoskeletal injuries diagnosis.

medicine.medical_specialtyStress fracturesSoft Tissue Injuriesbusiness.industryInfrared RaysPoison controlGeneral Medicinemedicine.diseaseFractures BoneRisk FactorsThermographyMeta-analysisInjury preventionThermographyMedical imagingmedicineInfrared thermal imagingPhysical therapyPrevalenceHumansRadiology Nuclear Medicine and imagingIn patientPractice Patterns Physicians'businessMuscle SkeletalAJR. American journal of roentgenology
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The use of topical corticosteroides in the treatment of oral lichen planus in Spain: A national survey

2017

Background Explore the treatment of oral lichen planus with topical corticosteroids by the healthcare professionals in Spain. Material and Methods A questionnaire targeted health professionals who treat OLP, in particular maxillofacial surgeons, dermatologist and dentist. The dissemination of the questionnaires was conducted through professional associations and dental and medical societies. The questionnaire was previously evaluated by means of a cognitive pre-test procedure to ensure that the questions were opportune and appropriate, understandable and acceptable among the professionals. Results Of the 890 questionnaires sent a total of 190 questionnaires were answered by 90 dentists, 60 …

medicine.medical_specialtyTriamcinolone acetonideAdministration TopicaleducationMEDLINEDentistry030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineCombined treatmentstomatognathic systemMedicineHumans030212 general & internal medicinePractice Patterns Physicians'skin and connective tissue diseasesGeneral DentistryGlucocorticoidsMaxillofacial surgeonsOral Medicine and Pathologyintegumentary systemHealth professionalsbusiness.industryResearch:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseDermatologystomatognathic diseasesOtorhinolaryngologyTopical corticosteroidSpainHealth Care SurveysUNESCO::CIENCIAS MÉDICASSurgeryOral lichen planusTreatment timeSelf Reportbusinessmedicine.drugLichen Planus Oral
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