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RESEARCH PRODUCT

Bilateral Ultrathin Descemet’s Stripping Automated Endothelial Keratoplasty vs. Bilateral Penetrating Keratoplasty in Fuchs’ Dystrophy: Corneal Higher-Order Aberrations, Contrast Sensitivity and Quality of Life

Giovannni CillinoSalvatore CillinoCasuccio AlessandraCostanza NovaraMaria VadalàVincenza BonfiglioCarla GiordanoValentina FaillaMassimo Castellucci

subject

medicine.medical_specialtyMedicine (General)Visual acuityDistance visual acuitygenetic structuresvisual acuitymedia_common.quotation_subjectmedicine.medical_treatmentFuchs' dystrophyArticleCohort StudiesR5-920Quality of lifeOphthalmologyhigher-order aberrationmedicineContrast (vision)HumansEye surgerymedia_commonRetrospective Studiescontrast sensitivityhigher-order aberrationsbusiness.industryFuchs' Endothelial DystrophyDystrophybilateral penetrating keratoplastyGeneral Medicinemedicine.diseasebilateral ultrathin DSAEKeye diseasesAberrations of the eyebilateral ultrathin DSAEK; bilateral penetrating keratoplasty; visual acuity; contrast sensitivity; higher-order aberrations; quality of lifequality of lifevisual acuity.medicine.symptombusinessDescemet Stripping Endothelial KeratoplastyKeratoplasty Penetrating

description

Background and Objectives: The objective of this paper is to compare the visual outcomes and quality of life (QoL) after bilateral ultrathin Descemet’s stripping automated endothelial keratoplasty (UT-DSAEK) with bilateral penetrating keratoplasty (PK) for Fuchs’ endothelial dystrophy (FED). Materials and Methods: Retrospective comparative cohort study, including 11 patients with FED who underwent bilateral PK and 13 patients with FED who underwent bilateral UT-DSAEK. All patients were already pseudophakic or had undergone a combined cataract procedure. The main outcomes were corrected distance visual acuity (CDVA) corneal higher-order aberrations (HOAs), contrast sensitivity (CS) and quality of life (QoL). Results: The mean follow-up after the second eye surgery was 32.5 ± 10.2 months in PK and 19.6 ± 8.6 months in UT-DSAEK patients. The CDVA in the UT-DSAEK group was significantly better than in the PK one (0.18 ± 0.07 vs. 0.35 ± 0.16 logMAR, p &lt

yearjournalcountryeditionlanguage
2021-02-03Medicina
10.3390/medicina57020133http://europepmc.org/articles/PMC7913208