Search results for "S-N"
showing 10 items of 292 documents
Immune networks: Multi-tasking capabilities at medium load
2013
Associative network models featuring multi-tasking properties have been introduced recently and studied in the low load regime, where the number $P$ of simultaneously retrievable patterns scales with the number $N$ of nodes as $P\sim \log N$. In addition to their relevance in artificial intelligence, these models are increasingly important in immunology, where stored patterns represent strategies to fight pathogens and nodes represent lymphocyte clones. They allow us to understand the crucial ability of the immune system to respond simultaneously to multiple distinct antigen invasions. Here we develop further the statistical mechanical analysis of such systems, by studying the medium load r…
Random walk approach to the analytic solution of random systems with multiplicative noise—The Anderson localization problem
2006
We discuss here in detail a new analytical random walk approach to calculating the phase-diagram for spatially extended systems with multiplicative noise. We use the Anderson localization problem as an example. The transition from delocalized to localized states is treated as a generalized diffusion with a noise-induced first-order phase transition. The generalized diffusion manifests itself in the divergence of averages of wavefunctions (correlators). This divergence is controlled by the Lyapunov exponent $\gamma$, which is the inverse of the localization length, $\xi=1/\gamma$. The appearance of the generalized diffusion arises due to the instability of a fundamental mode corresponding to…
Anderson localization problem: An exact solution for 2-D anisotropic systems
2007
Our previous results [J.Phys.: Condens. Matter 14 (2002) 13777] dealing with the analytical solution of the two-dimensional (2-D) Anderson localization problem due to disorder is generalized for anisotropic systems (two different hopping matrix elements in transverse directions). We discuss the mathematical nature of the metal-insulator phase transition which occurs in the 2-D case, in contrast to the 1-D case, where such a phase transition does not occur. In anisotropic systems two localization lengths arise instead of one length only.
Value-at-Risk and Tsallis statistics: risk analysis of the aerospace sector
2004
In this study, we analyze the aerospace stocks prices in order to characterize the sector behavior. The data analyzed cover the period from January 1987 to April 1999. We present a new index for the aerospace sector and we investigate the statistical characteristics of this index. Our results show that this index is well described by Tsallis distribution. We explore this result and modify the standard Value-at-Risk (VaR), financial risk assessment methodology in order to reflect an asset which obeys Tsallis non-extensive statistics.
Tunable multifunctional topological insulators in ternary Heusler compounds
2010
Recently the Quantum Spin Hall effect (QSH) was theoretically predicted and experimentally realized in a quantum wells based on binary semiconductor HgTe[1-3]. QSH state and topological insulators are the new states of quantum matter interesting both for fundamental condensed matter physics and material science[1-11]. Many of Heusler compounds with C1b structure are ternary semiconductors which are structurally and electronically related to the binary semiconductors. The diversity of Heusler materials opens wide possibilities for tuning the band gap and setting the desired band inversion by choosing compounds with appropriate hybridization strength (by lattice parameter) and the magnitude o…
Static and dynamical properties of a supercooled liquid confined in a pore
2000
We present the results of a Molecular Dynamics computer simulation of a binary Lennard-Jones liquid confined in a narrow pore. The surface of the pore has an amorphous structure similar to that of the confined liquid. We find that the static properties of the liquid are not affected by the confinement, while the dynamics changes dramatically. By investigating the time and temperature dependence of the intermediate scattering function we show that the dynamics of the particles close to the center of the tube is similar to the one in the bulk, whereas the characteristic relaxation time tau_q(T,rho) of the intermediate scattering function at wavevector q and distance rho from the axis of the p…
Spinodal decomposition in thin films: Molecular-dynamics simulations of a binary Lennard-Jones fluid mixture
2005
We use molecular dynamics (MD) to simulate an unstable homogeneous mixture of binary fluids (AB), confined in a slit pore of width $D$. The pore walls are assumed to be flat and structureless, and attract one component of the mixture (A) with the same strength. The pair-wise interactions between the particles is modeled by the Lennard-Jones potential, with symmetric parameters that lead to a miscibility gap in the bulk. In the thin-film geometry, an interesting interplay occurs between surface enrichment and phase separation. We study the evolution of a mixture with equal amounts of A and B, which is rendered unstable by a temperature quench. We find that A-rich surface enrichment layers fo…
HNRNPR Variants that Impair Homeobox Gene Expression Drive Developmental Disorders in Humans
2019
The heterogeneous nuclear ribonucleoprotein (HNRNP) genes code for a set of RNA-binding proteins that function primarily in the spliceosome C complex. Pathogenic variants in these genes can drive neurodegeneration, through a mechanism involving excessive stress-granule formation, or developmental defects, through mechanisms that are not known. Here, we report four unrelated individuals who have truncating or missense variants in the same C-terminal region of hnRNPR and who have multisystem developmental defects including abnormalities of the brain and skeleton, dysmorphic facies, brachydactyly, seizures, and hypoplastic external genitalia. We further identified in the literature a fifth ind…
Thermal inertia modeling for soil surface water content estimation: A laboratory experiment
2012
We are proposing a new method for estimating soil surface water content from thermal inertia distributions retrieved from visible–near infrared (VISNIR)and thermal infrared (TIR) images. A drying experiment was conducted on three fi ne-textured soils while acquiring multispectral VIS-NIR and TIR images. Simultaneous measurements of soil water content and thermal inertia were conducted by the thermogravimetric method and the heat pulse technique, respectively. Direct measurements were used to test the thermal inertia approach proposed by Murray and Verhoef that requires only knowledge of soil porosity and can be easily inverted to derive soil water content from thermal inertia. For the three…
The KH-type splicing regulatory protein (KSRP) regulates type III interferon expression post-transcriptionally.
2019
Abstract Type III interferons (IFNs) are the latest members of the IFN family. They play an important role in immune defense mechanisms, especially in antiviral responses at mucosal sites. Moreover, they control inflammatory reactions by modulating neutrophil and dendritic cell functions. Therefore, it is important to identify cellular mechanisms involved in the control of type III IFN expression. All IFN family members contain AU-rich elements (AREs) in the 3′-untranslated regions (3′-UTR) of their mRNAs that determine mRNA half-life and consequently the expressional level of these cytokines. mRNA stability is controlled by different proteins binding to these AREs leading to either stabili…