Search results for "SAC"

National Reports, Italy

2022

This text analyses the impact that a proposal for European harmonized rules on transaction avoidance law can have on Italian law.

Report on Italian Transaction Avoidance Law

2022

This text contains a report on Italian transaction avoidance law. It was written in order to contribute to an international project that massively influenced the European Commission in drawing up its "“Proposal for a Directive of the European Parliament and of the Council Harmonising Certain Aspects of Insolvency Law” – COM(2022) 702 final"

"Far-off gleams of evangelium" : a study of how J. R. R. Tolkien's The lord of the rings reflects the biblical "Kingdom of Heaven"

2008

“Il Disegno del Tempo”: due nuove installazioni per Kalenarte Museo all’Aperto di Casacalenda

2012

L'articolo ripercorre le tappe salienti della storia di Kalenarte, Museo all’Aperto di Casacalenda (CB) in Molise, recentemente oggetto di una importante ricerca del Ministero dei Beni e delle Attività Culturali - Direzione generale per il Paesaggio, le Belle Arti, l'Architettura e l'Arte Contemporanee dedicata ai più significativi i Luoghi del contemporaneo" in Italia.

Melittin Modulates Keratinocyte Function through P2 Receptor-dependent ADAM Activation

2012

Melittin, the major component of the bee venom, is an amphipathic, cationic peptide with a wide spectrum of biological properties that is being considered as an anti-inflammatory and anti-cancer agent. It modulates multiple cellular functions but the underlying mechanisms are not clearly understood. Here, we report that melittin activates disintegrin-like metalloproteases (ADAMs) and that downstream events likely contribute to the biological effects evoked by the peptide. Melittin stimulated the proteolysis of ADAM10 and ADAM17 substrates in human neutrophil granulocytes, endothelial cells and murine fibroblasts. In human HaCaT keratinocytes, melittin induced shedding of the adhesion molecu…

The Influence of Adalimumab and Cyclosporine A on the Expression Profile of the Genes Related to TGFβ Signaling Pathways in Keratinocyte Cells Treate…

2020

Background. In the treatment of moderate to severe psoriasis, cyclosporine A (CsA) conventional therapy is used and biological, anti-cytokine treatment using, for example, anti-TNF drug—adalimumab. Aim. This study aimed at investigating the effect of CsA and adalimumab on the profile of mRNAs and protein expression associated with transforming growth factor β (TGFβ) pathways in human keratinocyte (HaCaT) culture previously exposed to lipopolysaccharide (LPS). Materials and Methods. HaCaT culture was exposed to 1 ng/ml LPS for 8 hours+8 μg/ml adalimumab for 2, 8, and 24 hours or 1 ng/ml LPS for 8 hours+100 ng/ml CsA for 2, 8, and 24 hours and compared to the control culture. Sulphorodamine B…

2019

Aims To report corneal topometric and aberrometric values in mucopolysaccharidosis (MPS) and to investigate their correlation with biomechanical corneal parameters. Methods One randomly chosen eye of 20 MPS patients with no to moderate corneal clouding and one eye of 23 healthy controls with comparable age were prospectively included into this study. Corneal surface regularity was assessed by index of surface variance (ISV), -vertical asymmetry (IVA), -height asymmetry (IHA), -height decentration (IHD); keratoconus index (KI), central keratoconus index (CKI) and Zernike indices of anterior and posterior corneal surface using Scheimpflug imaging (Pentacam). Corneal resistance factor (CRF) an…

Relation between structural and release properties in a polysaccharide gel system.

2007

Abstract The potential utility of κ-carrageenan gels for preparing drug release devices is here shown. Structural properties of κ-carrageenan gels prepared with different salt composition and containing Ketoprofen sodium salt, as model drug, have been evaluated with static light scattering and rheological measurements. These properties have been correlated with release profiles in vitro at pH 5.5. Release properties from gelled matrices have been compared with those obtained by two commercial products containing the same drug. Results show that: i) in this system it is possible to easily control the gel texture by using different cationic concentration; ii) the kinetics of drug release by κ…

Mannoproteins from the cell wall ofKluyveromyces lactis

1986

Wall mannoproteins from Kluyveromyces lactis have been solubilised by treatment of cell walls with sodium dodecyl sulphate (SDS) or zymolyase. While the former reagent liberates a large number of molecular species, zymolyase preferentially releases a high-molecular-weight material that is sensitive to endo-β-N-acetylglucosaminidase H, and a 29-kDa molecule that reacts with the antiserum raised against a similar species from walls of Saccharomyces cerevisiae. In contrast with observations on isolated walls of S. cerevisiae, dithiothreitol pretreatment of K. lactis walls does not enhance the effect of zymolyase upon mannoprotein release. However, the action of thiol agents is still necessary …

Collaborative Educational Leadership: The Emergence of Human Interactional Sense-Making Process as a Complex System

2014

The article aims at explicating the emergence of human interactional sense‐making process within educational leadership as a complex system. The kind of leadership is understood as a holistic entity called collaborative leadership. There, sense‐making emerges across interdependent domains, called attributes of collaborative leadership. The attributes give rise to the complex system. They are suggested to be the very agents, i.e. both the source and the outcome of the synergetic sense‐making process. Hence, the agents are not the single persons involved who, however, supply the collective attributes that are modified through human interaction in a holistic way. For studying the emergence pro…