Search results for "SAF"

showing 10 items of 2183 documents

High dose inhalation interleukin-2 therapy for lung metastases in patients with malignant melanoma.

2000

BACKGROUND The lungs are a frequent site of metastasis in patients with melanoma, and this may cause respiratory problems in the terminal phase of the illness. Inhalation interleukin (IL)-2 therapy to the lung has been piloted and appears to be well tolerated. METHODS Twenty-seven patients were treated with single agent dacarbazine and concurrent high dose inhalation IL-2 36 million IU per day). The patients previously had progressed on chemotherapy, predominately dacarbazine-based regimens. Patients included those with American Joint Committee on Cancer Stage IV melanoma, predominately those with lung metastases, but patients with extrapulmonary metastases also were allowed on the study. R…

MaleCancer Researchmedicine.medical_specialtyLung NeoplasmsDacarbazinemedicine.medical_treatmentAntineoplastic AgentsGastroenterologyMetastasisInternal medicineCause of DeathAdministration InhalationAntineoplastic Combined Chemotherapy ProtocolsmedicineHumansAntineoplastic Agents AlkylatingMelanomaChemotherapyInhalationbusiness.industryMelanomaRespiratory diseaseRemission InductionCancerReproducibility of ResultsConfounding Factors Epidemiologicmedicine.diseaseRecombinant ProteinsSurgeryDacarbazineTreatment OutcomeOncologyConcomitantDisease ProgressionInterleukin-2FemaleSafetybusinessmedicine.drugFollow-Up StudiesCancer
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Analysis of 126 hospitalized elder maxillofacial trauma victims in central China

2014

Background: The aim of this study was to analyzed the characteristics and treatment of maxillofacial injuries in the elder patients with maxillofacial injuries in central China. Material and Methods: We retrospectively analyzed the characteristics and treatment of maxillofacial injuries in the patients over the age of 60 to analyze the trends and clinical characteristics of maxillofacial trauma in elder patients from the First Affiliated Hospital of Zhengzhou University (from 2010 to 2013) in central China and to present recommendations on prevention and management. Results: Of the 932 patients with maxillofacial injuries, 126 aged over 60 years old accounting for 13.52% of all the patients…

MaleChinamedicine.medical_specialtymedicine.medical_treatmentPoison controlOdontologíaOccupational safety and healthInjury preventionmedicineHumansInternal fixationGeneral DentistryAgedRetrospective StudiesAged 80 and overbusiness.industryResearchSoft tissueHuman factors and ergonomicsRetrospective cohort studyMiddle Aged:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludSurgeryHospitalizationClinical researchOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASPractice Guidelines as TopicFemaleMaxillofacial InjuriesSurgeryOral SurgerybusinessMedicina Oral Patología Oral y Cirugia Bucal
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Week 96 efficacy and safety results of the phase 3, randomized EMERALD trial to evaluate switching from boosted-protease inhibitors plus emtricitabin…

2019

Darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) 800/150/200/10 mg was investigated through 96 weeks in EMERALD (NCT02269917). Virologically-suppressed, HIV-1-positive treatment-experienced adults (previous non-darunavir virologic failure [VF] allowed) were randomized (2:1) to D/C/F/TAF or boosted protease inhibitor (PI) plus emtricitabine/tenofovir-disoproxil-fumarate (F/TDF) over 48 weeks. At week 52 participants in the boosted PI arm were offered switch to D/C/F/TAF (late-switch, 44 weeks D/C/F/TAF exposure). All participants were followed on D/C/F/TAF until week 96. Efficacy endpoints were percentage cumulative protocol-defined virologic rebound (PDVR; confirmed vira…

MaleDOLUTEGRAVIRSustained Virologic ResponseHIV InfectionsGastroenterologychemistry.chemical_compound0302 clinical medicineMedicine and Health SciencesEmtricitabine030212 general & internal medicinePharmacology & PharmacyDarunavir0303 health sciencesAlanineDrug SubstitutionCobicistatEmtricitabine Tenofovir Disoproxil Fumarate Drug CombinationLamivudineAntiretroviralsMiddle AgedViral LoadOPEN-LABEL3. Good healthWEIGHT-GAINDrug CombinationsTreatment OutcomeDolutegravirNON-INFERIORITYFemaleSafetyViral loadLife Sciences & Biomedicinemedicine.drugTabletsAdultmedicine.medical_specialtyEfficacyAnti-HIV AgentsRITONAVIREmtricitabineTENOFOVIR ALAFENAMIDELAMIVUDINETenofovir alafenamideSingle-tablet regimen03 medical and health sciencesInternal medicineVirologymedicineVIH (Virus)HumansSwitch studyProtease InhibitorsTenofovirDarunavirAgedPharmacologyScience & Technology030306 microbiologybusiness.industryHIV (Viruses)AdenineDarunavir/cobicistat/emtricitabine/TAFAntiretroviral agentsCOBICISTATMAINTENANCEchemistry[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologieHIV-1RitonavirCobicistat[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologiebusinessRESISTANCE
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Efficacy and safety of combined diclofenac 0.1 % and gentamicin 0.3 eyedrops after phacoemulsification

1997

To study the efficacy of combined diclofenac 0.1% and gentamicin 0.3% (Digen) eyedrops to treat postoperative inflammation and prevent ocular infection in eyes having phacoemulsification.Department of Ophthalmology, University of Milan, San Paolo Hospital, Milan; Eye Clinic, University of Verona; and Department of Ophthalmology, University of Palermo, Italy.This double-masked, randomized, clinical trial comprised 90 patients; 45 received Digen and 45, gentamicin 0.3% eyedrops. The main outcome measure of the study was the reduction in signs and symptoms of inflammation, graded on a four-point scale. Also assessed were the presence of bacteria in the conjunctival swab and the proportion of p…

MaleDiclofenacAdministration Topicalmedicine.medical_treatmentEye diseaseEye Infections BacterialDiclofenacDouble-Blind MethodmedicineHumansAgedRetrospective StudiesAntibacterial agentAged 80 and overEndophthalmitisPhacoemulsificationbusiness.industryAnti-Inflammatory Agents Non-SteroidalAminoglycosideEye dropPhacoemulsificationMiddle Agedmedicine.diseaseSensory SystemsAnti-Bacterial AgentsClinical trialOphthalmologyTreatment OutcomeAnesthesiaDrug Therapy CombinationFemaleSurgeryGentamicinGentamicinsOphthalmic SolutionsSafetybusinessmedicine.drugJournal of Cataract and Refractive Surgery
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Epidemiology of children's swimming competence and water safety.

2022

IntroductionThe main purpose of this study was to investigate children's swimming competence in primary schools of districts in Vojvodina, Serbia.MethodsIncluded subjects were primary school students from first to eighth grade (N = 2,778; male = 1,454, female = 1,324; age = 10.73 ± 2.1 years). We used Swimming Competence Questionnaire to acquire and analyze their swimming experience, non-fatal aquatic events, and demographics. For the statistical analysis, logistic regression and hierarchical multiple regression were used to evaluate if the factors and SC and NFAE were associated. The analyses were carried out by using SPSS® software version 24.0 (SPSS, Inc., Chicago, Illinois, USA).Results…

MaleDrowningschool childrenPublic Health Environmental and Occupational Healthswimming skillsWaterSurveys and Questionnairesschool children drowning safety measures swimming skills aquatic eventsaquatic eventsEducational StatusHumansFemalesafety measuresChildSwimmingFrontiers in public health
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Job stress and emotional exhaustion at work in Spanish workers: Does unhealthy work affect the decision to drive?

2020

Objectives The purpose of this study was to assess the relationships among the following elements: unhealthy work indicators (job stress and emotional exhaustion at work), the decision to drive (or not), and driving crashes suffered by Spanish workers. Methods For this cross-sectional study, a full sample of 1,200 Spanish drivers (44% women and 56% men) was used, their mean age being 42.8 years. They answered a questionnaire divided into three sections: demographic and driving-related data; burnout, job stress, and life stress; and self-reported road behaviors and driving safety indicators. Results Overall, 41.6% of drivers reported emotional exhaustion at work. Furthermore, 80.2% of the pa…

MaleEconomicsEmotionsSocial SciencesPoison controlTransportationBurnoutPathology and Laboratory MedicineOccupational safety and healthOccupational Stress0302 clinical medicineSociologySurveys and QuestionnairesMedicine and Health SciencesPsychologyPublic and Occupational Health030212 general & internal medicineWorkplaceEmotional exhaustionBurnout ProfessionalFatigueMultidisciplinarySeguretat viàriaQ05 social sciencesRHuman factors and ergonomicsMiddle AgedTransportation InfrastructureSocial SystemsEngineering and TechnologyMedicineFemaleJob satisfactionSafetyPsychologyResearch ArticleClinical psychologyEmploymentAdultAutomobile DrivingSciencePsychological StressJobsAffect (psychology)Civil EngineeringJob Satisfaction03 medical and health sciencesSigns and SymptomsDiagnostic MedicineMental Health and Psychiatry0502 economics and businessInjury preventionHumansBehaviorTraffic SafetyBiology and Life SciencesRoadsPsicologiaSpainLabor EconomicsSelf Reporthuman activities050203 business & managementPLOS ONE
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Medical Support for Children's Mass Gatherings

2003

AbstractIntroduction:Medical care must be well-planned for mass gatherings. Events such as fairs, concerts, parades, and rallies cause many people to gather in one place, increasing the chance of injuries and for the development of a disaster. In this study, the level and quality of medical care were evaluated at a mass gathering of approximately 100,000 children. The event was a television-sponsored fun fair.Methods:Every patient contact was documented on printed forms, including data such as the number of patients treated, gender of the patients, presence or absence of a parental escort, time distribution of patient contacts, the diagnoses for the patient contacts, specific therapies appl…

MaleEmergency Medical ServicesPediatricsmedicine.medical_specialtyAdolescentChild Health ServicesPoison controlEmergency NursingSuicide preventionOccupational safety and healthGermanyMass gatheringInjury preventionmedicineHumansMedical diagnosisChildEmergency TreatmentParentingbusiness.industryMajor traumamedicine.diseaseAnniversaries and Special EventsCrowdingOutcome and Process Assessment Health CareTransportation of PatientsEmergency medicineEmergency MedicineFemaleEmergenciesHeadachesmedicine.symptombusinessMass BehaviorTotal Quality ManagementPrehospital and Disaster Medicine
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The violence of men against women: Medico-legal and psychological issues

2019

Violence against women breaches women’s human rights and is a global public health issue that can cause devastating life-long damage. This study considers the characters of victims, abusers and traumatic bonding in heterosexual couples from a medico-legal and psycological standpoint. After considering the devastating effects on women’s health, and with the objective of preventing future violence, it illustrates the weaknesses and strengths of new Italian guidelines related to violence against women in emergency departments including the use of “Brief Risk Assessment for IPV in the Emergency Department – DA5”.

MaleEmergency Medical Servicesmedicine.medical_specialtymedia_common.quotation_subjectIntimate Partner ViolencePoison controlGuidelines as Topicbrief risk assessment Intimate partner violence Italian guidelines for emergency department physical–psychological violence women’s healthCriminologySuicide preventionOccupational safety and health03 medical and health sciences0302 clinical medicineInjury preventionmedicineHumans0501 psychology and cognitive sciences030212 general & internal medicinemedia_commonHuman rightsPublic health05 social sciencesHuman factors and ergonomicsGeneral MedicinehumanitiesItalyDomestic violenceFemalePsychology050104 developmental & child psychologyMedico-Legal Journal
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Influence of sexual appeal in roadside advertising on drivers' attention and driving behavior.

2019

Sexual appeals are widely used in advertising to attract consumers' attention. It has already been proved that they influence the addressee's cognitive processing, which in turn raises the question if sexual appeals may pose a serious threat for road safety when used in roadside advertising. Three studies were designed to answer this question. Study I was a nationwide survey (N = 1095) which revealed that drivers subjectively perceive sexual contents in roadside advertising as distracting and dangerous. Study II was a modified version of the Attentional Network Test (N = 1063) which proved that in cognitive tasks reaction time increases in line with the sexual content of advertisements. Stu…

MaleEmotionsSocial SciencesTransportationNationwide surveyCognitionSociologyAdvertisingMedicine and Health SciencesPsychologyAttentionPublic and Occupational Health050107 human factorsAged 80 and overMarketingMultidisciplinaryQ05 social sciencesRCognitionAdvertisingMiddle AgedAutomobile drivingTransportation InfrastructureTest (assessment)MedicineEngineering and TechnologyFemaleSafetyPsychologyResearch ArticleAdultElementary cognitive taskAutomobile DrivingAdolescentScienceCognitive NeuroscienceCivil Engineering0502 economics and businessReaction TimeHumans0501 psychology and cognitive sciencesAged050210 logistics & transportationBehaviorSexual attractionCognitive PsychologyTraffic SafetyBiology and Life SciencesCommunicationsRoadsCognitive ScienceAttentional networkHuman Sexual BehaviorNeurosciencePloS one
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Description of dynamic shared knowledge: an exploratory study during a competitive team sports interaction.

2011

This exploratory case study describes the sharedness of knowledge within a basketball team (nine players) and how it changes during an official match. To determine how knowledge is mobilised in an actual game situation, the data were collected and processed following course-of-action theory (Theureau 2003). The results were used to characterise the contents of the shared knowledge (i.e. regarding teammate characteristics, team functioning, opponent characteristics, opposing team functioning and game conditions) and to identify the characteristic types of change: (a) the reinforcement of a previous element of shared knowledge; (b) the invalidation of an element of shared knowledge; (c) fragm…

MaleEngineeringCompetitive BehaviorKnowledge managementTeam sportAdolescentmedia_common.quotation_subjectExploratory researchVideo RecordingPhysical Therapy Sports Therapy and RehabilitationHuman Factors and ErgonomicsPsychological safetyBasketball03 medical and health sciences0302 clinical medicineCognitionHumans0501 psychology and cognitive sciencesRelevance (information retrieval)Cooperative Behavior050107 human factorsQualitative Researchmedia_commonTeam compositionTeamworkbusiness.industry05 social sciencesCommon groundCognition030229 sport sciencesKnowledgeTape RecordingErgonomicsFrancebusinessSportsErgonomics
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