Search results for "SAF"

A systematic overview of the first pasteurised VWF/FVIII medicinal product, Haemate P/Humate -P: history and clinical performance

2008

Patients with von Willebrand disease (VWD) and haemophilia A (HA) lack, to varying degrees, the von Willebrand factor (VWF) and coagulation factor VIII (FVIII) that are critical for normal haemostasis. These conditions in turn make patients prone to uncontrolled bleeding. Historically, patients with severe forms of VWD or HA were crippled before adulthood and their life expectancy was significantly reduced. Over the past decades, specific coagulation factor replacement therapies including Haemate P, have been developed to help patients achieve and maintain normal haemostasis. Haemate P is a human, plasma-derived VWF/FVIII medicinal product, which was first licensed in Germany in 1981 for th…

Editorial : Conservative dispositions in continental thought

2022

Mothers’ non-standard working schedules and family time : enhancing regularity and togetherness

2016

Purpose – The purpose of this paper is to investigate Finnish working mothers’ experiences of the effects of non-standard working schedules (NSWS) on family time in two family forms, coupled and lone-parent families. Furthermore the aim is to find out what meanings mothers with NSWS attached to family time paying particular attention to the circumstances in which mothers experienced NSWS positively. Design/methodology/approach – Thematic analysis of 20 semi-structured interviews was used to investigate mothers’ experiences of the effects of NSWS on family time. Findings – The key factor generating positive experiences was the ability to maintain regularity and togetherness, which was enhan…

Beneficial effects of saffron (

2020

Saffron (Crocus sativus L.) has been traditionally used in food preparation and as a medicinal plant. It currently has numerous therapeutic properties attributed to it, such as protection against ischemia, as well as anticonvulsant, antidepressant, anxiolytic, hypolipidemic, anti-atherogenic, anti-hypertensive, antidiabetic, and anti-cancer properties. In addition, saffron has remarkable beneficial properties, such as anti-apoptotic, anti-inflammatory and antioxidant activities, due to its main metabolites, among which crocin and crocetin stand out. Furthermore, increasing evidence underwrites the possible neuroprotective role of the main bioactive saffron constituents in neurodegenerative …

Effects of Genotype and Climate on Productive Performance of High Oleic Carthamus tinctorius L. under Rainfed Conditions in a Semi-Arid Environment o…

2023

Safflower (Carthamus tinctorius L.) is a promising oilseed crop for cultivation in central Southern Italy due to its high tolerance to drought and salinity stress and appreciable seed and oil yields. The genetic diversity of cultivars and climate factors can affect fatty acid composition and yield traits. This study aimed to assess the effects of genotype and climate conditions on the productive performance of eight high oleic safflower genotypes under rainfed conditions in Sicily (Italy). These genotypes were compared to the Montola 2000 cultivar, which was used as a reference. Tests were carried out during the growing seasons of 2014–2015 and 2015–2016. The experimental design…

Use of Battery- vs. Petrol-Powered Chainsaws in Forestry: Comparing Performances on Cutting Time

2022

The use of battery tools is very common in many fields of work. In fact, the electric engine and batteries have several advantages over traditional endothermic engines, including low emissions, in terms of pollutants, vibration and noise. In this context, the chainsaw market started producing electric models powered by batteries. These machines can be useful in forestry, but information on their performance is scarce. The aim of this work was to compare the performance, in terms of cutting times, of three Stihl chainsaw models: the MS 220C-B (battery powered), and the MS 201 C-M and MS 261 C-M (both petrol powered). The study was carried out on five different wood species, also taking into …

Developing and Validating a Behavioural Model of Cyberinsurance Adoption

2021

Business disruption from cyberattacks is a growing concern, yet cyberinsurance uptake remains low. Using an online behavioural economics experiment with 4800 participants across four EU countries, this study tests a predictive model of cyberinsurance adoption, incorporating elements of Protection Motivation Theory (PMT) and the Theory of Planned Behaviour (TPB) as well as factors in relation to risk propensity and price. During the experiment, participants were given the opportunity to purchase different cybersecurity measures and cyberinsurance products before performing an online task. Participants likelihood of suffering a cyberattack was dependent upon their adoption of cybersecurity me…

La tutela dei dati scientifici nel regolamento sui novel food alla luce del regolamento in materia di health e nutritional claims.

2021

Il regolamento (UE) 2283/2015 sui novel food rappresenta un’evoluzione nella protezione dei dati scienti ci relativi ai nuovi prodotti alimentari. La normativa, sviluppata sul modello offerto dal regolamento (UE) 1924/2006 in materia di indicazioni nutrizionali e sulla salute, garantisce una protezione quinquennale dei dati scienti ci e delle prove pro- dotte dal richiedente in sede di domanda di autorizzazione di un nuovo prodotto ex art. 10 del regolamento (UE) 2283/2015. La previsione di un termine quinquennale di tutela se, secondo taluni, può risultare troppo breve per rappresentare un vero incentivo per compiere investimenti in ricerca e sviluppo da parte delle imprese; d’altra parte…

Criticità della tutela dei dati scientifici nel regolamento sui nuovi alimenti anche alla luce della disciplina in materia di benessere degli animali

2021

Il regolamento (UE) 2283/2015 sui novel food rappresenta un’evoluzione nella protezione dei dati scientifici relativi ai nuovi prodotti alimentari. La normativa, sviluppata sul modello offerto dal regolamento (UE) 1924/2006 in materia di indicazioni nutrizionali e sulla salute, garantisce una protezione quinquennale dei dati scienti ci e delle prove pro- dotte dal richiedente in sede di domanda di autorizzazione di un nuovo prodotto ex art. 10 del regolamento (UE) 2283/2015. La previsione di un termine quinquennale di tutela se, secondo taluni, può risultare troppo breve per rappresentare un vero incentivo per compiere investimenti in ricerca e sviluppo da parte delle imprese; d’altra part…

DISTRIBUTING RESPONSIBILITY BETWEEN SHIPMASTERS AND THE DIFFERENT STATES INVOLVED IN SAR DISASTERS

2019

The duty to save life at sea can today be considered a rule of general inter- national law. However, the concept of “duty to save life at sea” hides a complex web of international regulations, scattered across several treaties providing obli- gations both for shipmasters and a plurality of States (namely flag States, coastal States, States receiving distress signals, etc.). This paper addresses the question of the respective responsibility of the different subjects involved in search and res- cue activities. After a short introduction to the evolution of international law in this field, the paper investigates the relationship between shipmasters and States. This first part of the study show…