Search results for "SAHA"

showing 10 items of 198 documents

Éducation primaire et croissance économique en Afrique subsaharienne : les conditions d'une relation efficace

1995

This article is looking at the causes of the low effectiveness of educational investment in Subsaharan Africa, both at the micro level (effect on labour productivity), and at the macro level (effect on the rate of economic growth). Several recent empirical studies have shown that education impact is systematically weaker in this region than in the rest of the world, and even sometimes negative, as in the case of agricultural productivity. Two series of causes may explain this lack of impact : first, inappropriate economic policies at the macro level which hamper the role of education, either through negative incentives structures, or because of the absence of provision of associated factors…

2. Zero hunger050208 finance030505 public healthCroissance économique[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/Education05 social sciences1. No povertyDevelopmentAfrique subsaharienneEnseignement primaireRelation éducation-croissance03 medical and health sciencesAfriqueÉcole primaire8. Economic growth0502 economics and business0305 other medical scienceGeneral Economics Econometrics and Finance

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Histone deacetylase inhibition by suberoylanilide hydroxamic acid: a therapeutic approach to treat human uterine leiomyoma.

2022

Objective To evaluate the effect of inhibition of histone deacetylases (HDACs) by suberoylanilide hydroxamic acid (SAHA) treatment of human uterine leiomyoma primary (HULP) cells in vitro on cell proliferation, cell cycle, extracellular matrix (ECM) formation, and transforming growth factor β3 (TGF-β3) signaling. Design Prospective study comparing uterine leiomyoma (UL) vs. adjacent myometrium (MM) tissue and cells with or without SAHA treatment. Setting Hospital and university laboratories. Patient(s) Women with UL without any hormone treatment. Intervention(s) Myomectomy or hysterectomy surgery in women for leiomyoma disease. Main Outcome Measure(s) HDAC activity was assessed by enzyme-li…

AdultAntineoplastic AgentsHistone Deacetylase 1MMP9Histone Deacetylase 6Histone DeacetylasesCyclin D1Transforming Growth Factor beta3Cell proliferation SAHA ULS-ß3 pathway extracellular matrix uterine leiomyomaTumor Cells CulturedHumansViability assayProspective StudiesCell ProliferationVorinostatbiologyLeiomyomaChemistryCell growthCell CycleObstetrics and GynecologyCell cycleMiddle AgedHDAC3Molecular biologyProliferating cell nuclear antigenExtracellular MatrixGene Expression Regulation NeoplasticHistone Deacetylase InhibitorsReproductive MedicineUterine Neoplasmsbiology.proteinFemaleHistone deacetylaseSignal TransductionFertility and sterility

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An integrated model of condom use in Sub-Saharan African youth: A meta-analysis.

2017

Objective: We tested an integrated social–cognitive model derived from multiple theories of the determinants of young people's condom use in Sub-Saharan Africa. The model comprised seven social–cognitive antecedents of condom use: Attitudes, norms, control, risk perceptions, barriers, intentions, and previous condom use. Method: We conducted a systematic search of studies including effects between at least one model construct and intended or actual condom use in young people from sub-Saharan African countries. Fifty-five studies comprising 72 independent data sets were included and subjected to random-effects meta-analysis. Demographic and methodological variables were coded as moderators. …

AdultMaleAdolescentSexual BehaviorPsychological interventionPsycINFOSocial and Behavioral SciencesArticleStructural equation modelinglaw.inventionDevelopmental psychologyCondomsAfrikkaYoung Adult03 medical and health sciences0302 clinical medicinenuoretCondomSocial cognitionlawHumans030212 general & internal medicineChildAfrica South of the SaharaApplied Psychologykondomit030505 public healthmeta-analyysiExplained variationModerationPsychiatry and Mental healthterveyskäyttäytyminenMeta-analysisAfricaFemale0305 other medical sciencePsychologyHealth Psychology

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Disparités sociales en éducation en Afrique sub-saharienne : Genre, localisation géographique et revenu du ménage

2006

06017; Dans ce texte, nous poursuivons deux objectifs complémentaires : le premier consiste à offrir une description de l'ampleur des disparités sociales qui existent dans les systèmes éducatifs des pays de l'Afrique au Sud du Sahara principalement dans la période actuelle mais aussi en lui donnant une perspective temporelle; le second cherche à identifier certains des facteurs qui peuvent rendre compte des disparités constatées ou des actions qui ont visé à les réduire.

Afrique sub-saharienne[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationDisparités sociales[ SHS.EDU ] Humanities and Social Sciences/EducationSocial disparitiesSubsaharan AfricaEducational systemDisparités socialesAfrique sub-saharienneEducationSystème éducatif[SHS.ECO]Humanities and Social Sciences/Economics and FinanceSystème éducatifEducationSubsaharan Africa[ SHS.ECO ] Humanities and Social Sciences/Economies and financesSocial disparities[SHS.ECO] Humanities and Social Sciences/Economics and FinanceEducational system

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Cost and Financing of Education and its Impact on Coverage and Quality of Services and Efficiency and Equity in Sub-Saharan African Countries

2007

07052; In this chapter, we take mostly an international comparative perspective limited to Sub-Saharan African countries. First, we analyse first the macro picture and the public finance dimension, analyzing the systemic choices made in the distribution of public resources across levels and types of education. Second, we move to unit cost estimates and the factors accounting for their level in a given country and to their variation across the different countries of the region. Finally, we examine the implication of the choices made in the financial dimension upon outcomes (coverage and quality of educationl services), birnging issues of efficiency and equity into the analysis.