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showing 10 items of 2270 documents

Rat liver preservation by hypothermic oscillating liver perfusion compared to simple cold storage.

1998

Rat livers were preserved hypothermically for 10 or 24 h in vitro as if for transplantation. Two methods of preservation were compared using physiological and biochemical parameters: simple storage and oscillating perfusion. By measuring the nucleotides after preservation the calculated energy charge was significantly higher after 10 and 24 h of oscillating perfusion compared to the simple storage group. In addition, a significant energy charge loading was demonstrated by 10 h oscillating perfusion compared to the initial value prior to perfusion. The oscillating, computer-controlled perfusion permits continuous monitoring of perfusate temperature, O2 consumption, pCO2, portal vein pressure…

MalePathologymedicine.medical_specialtyBiomedical EngineeringCold storageBlood PressureIn Vitro TechniquesGeneral Biochemistry Genetics and Molecular BiologypCO2Oxygen ConsumptionAdenine nucleotideOscillometryRats Inbred BNmedicineAnimalsEnergy chargeCryopreservationL-Lactate DehydrogenaseChemistryAdenine NucleotidesGeneral MedicineOrgan PreservationHydrogen-Ion Concentrationmedicine.diseaseLiver GlycogenRatsTransplantationCold TemperaturePerfusionLiverEvaluation Studies as TopicReperfusion InjurySample collectionGeneral Agricultural and Biological SciencesReperfusion injuryPerfusionGlycolysisBiomedical engineeringCryobiology
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Identification of the nuclear factor kappa-beta (NF-kB) in cortical of mice Wistar using Technovit 7200 VCR

2009

Objective: this study aimed to develop a nondecalcified bone sample processing technique enabling immunohistochemical labeling of proteins by kappa-beta nuclear factor (NF-kB) utilizing the Technovit 7200 VCR® in adult male Wistar rats. Study Method: A 1.8 mm diameter defect was performed 0.5mm from the femur proximal joint by means of a round bur. Experimental groups were divided according to fixing solution prior to histologic processing: Group 1- ethanol 70%; Group 2-10% buffered formalin; and Group 3- Glycerol diluted in 70% ethanol at a 70/30 ratio + 10% buffered formalin. The post-surgical periods ranged from 01 to 24 hours. Control groups included a nonsurgical procedure group (NSPG)…

MalePathologymedicine.medical_specialtyPositive reactionSample processingAcrylic ResinsPositive controlBone and BonesMicechemistry.chemical_compoundmedicineAnimalsFemurRats WistarBeta (finance)General DentistryEthanolbusiness.industryNF-kappa B:CIENCIAS MÉDICAS [UNESCO]ImmunohistochemistryRatsOtorhinolaryngologychemistryUNESCO::CIENCIAS MÉDICASImmunohistochemistrySurgeryNuclear medicinebusinessKappa
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Trends in the prevalence of asthma and allergic rhinitis in Italy between 1991 and 2010

2012

The prevalence of asthma increased worldwide until the 1990s, but since then there has been no clear temporal pattern. The present study aimed to assess time trends in the prevalence of current asthma, asthma-like symptoms and allergic rhinitis in Italian adults from 1990 to 2010. The same screening questionnaire was administered by mail or phone to random samples of the general population (age 20-44 yrs) in Italy, in the frame of three multicentre studies: the European Community Respiratory Health Survey (ECRHS) (1991-1993; n=6,031); the Italian Study on Asthma in Young Adults (ISAYA) (1998-2000; n=18,873); and the Gene Environment Interactions in Respiratory Diseases (GEIRD) study (2007-2…

MalePediatricsCross-sectional study95% CI 1.19-1.59) from 1998-2000 to 2007-2010but since then there has been no clear temporal pattern. The present study aimed to assess time trends in the prevalence of current asthmaAbstract The prevalence of asthma increased worldwide until the 1990stemporal trendsSurveys and QuestionnairesEpidemiologySurveys and QuestionnaireMedicineasthma-like symptoms and allergic rhinitis in Italian adults from 1990 to 2010. The same screening questionnaire was administered by mail or phone to random samples of the general population (age 20-44 yrs) in ItalyYoung adultrespectively. The prevalence of current asthma was stable during the 1990s and increased (relative risk 1.38from 10.1% to 13.9% and from 16.8% to 25.8%education.field_of_studyAllergic rhinitis; Asthma; Epidemiology; Prevalence; Temporal trends; Wheezing;medicine.diagnostic_testSmokingthe median prevalence of current asthmaallergic rhinitis asthma epidemiology prevalence temporal trends wheezingItalyAbstract The prevalence of asthma increased worldwide until the 1990s but since then there has been no clear temporal pattern. The present study aimed to assess time trends in the prevalence of current asthma asthma-like symptoms and allergic rhinitis in Italian adults from 1990 to 2010. The same screening questionnaire was administered by mail or phone to random samples of the general population (age 20-44 yrs) in Italy in the frame of three multicentre studies: the European Community Respiratory Health Survey (ECRHS) (1991-1993; n=6031); the Italian Study on Asthma in Young Adults (ISAYA) (1998-2000; n=18873); and the Gene Environment Interactions in Respiratory Diseases (GEIRD) study (2007-2010; n=10494). Time trends in prevalence were estimated using Poisson regression models in the centres that repeated the survey at different points in time. From 1991 to 2010 the median prevalence of current asthma wheezing and allergic rhinitis increased from 4.1% to 6.6% from 10.1% to 13.9% and from 16.8% to 25.8% respectively. The prevalence of current asthma was stable during the 1990s and increased (relative risk 1.38 95% CI 1.19-1.59) from 1998-2000 to 2007-2010 mainly in subjects who did not report allergic rhinitis. The prevalence of allergic rhinitis has increased continuously since 1991. The asthma epidemic is not over in Italy. During the past 20 yrs asthma prevalence has increased by 38% in parallel with a similar increase in asthma-like symptoms and allergic rhinitis.mainly in subjects who did not report allergic rhinitis. The prevalence of allergic rhinitis has increased continuously since 1991. The asthma epidemic is not over in Italy. During the past 20 yrssymbolsasthma prevalence has increased by 38%FemaleepidemiologyHumanPulmonary and Respiratory MedicineAdult494). Time trends in prevalence were estimated using Poisson regression models in the centres that repeated the survey at different points in time. From 1991 to 2010in parallel with a similar increase in asthma-like symptoms and allergic rhinitismedicine.medical_specialtyRhinitis Allergic PerennialPopulationprevalencethe Italian Study on Asthma in Young Adults (ISAYA) (1998-2000Settore MED/10 - Malattie Dell'Apparato Respiratorio031)and the Gene Environment Interactions in Respiratory Diseases (GEIRD) study (2007-2010Settore MED/01 - Statistica Medicasymbols.namesakeYoung AdultAllergic rhinitiHumansRespiratory soundsPoisson regressioneducationAsthmaRespiratory SoundsCross-Sectional Studieallergic rhinitisbusiness.industrywheezingwheezing and allergic rhinitis increased from 4.1% to 6.6%Rhinitis Allergic Seasonalasthmain the frame of three multicentre studies: the European Community Respiratory Health Survey (ECRHS) (1991-1993medicine.disease873)Cross-Sectional Studiesn=10Relative riskTemporal trendRespiratory Soundn=6n=18business
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Rising Stroke Incidence in Young Adults: More Epidemiological Evidence, More Questions to Be Answered

2016

Studies have reported increasing incidence of ischemic stroke in adults younger than 50 to 55 years. Information on temporal trends of other stroke subtypes and transient ischemic attack (TIA) is sparse. The aim of this study was to investigate temporal trends of the incidence of hospitalizations for TIA and stroke including sex- and subtype-specific trends in young adults aged 15 to 30 years.From the Danish National Patient Register, we identified all cases of first-ever stroke and TIA (age 15-30 years) in Denmark, who were hospitalized during the study period of 1994 to 2012. Incidence rates and estimated annual percentage changes (EAPCs) were estimated by using Poisson regression. During…

MalePediatricsDenmarkPrevalencepopulation030204 cardiovascular system & hematologyburden0302 clinical medicineRisk FactorsCardiovascular DiseaseEpidemiologyMedicinePoisson DistributionRegistriesYoung adultStrokeComputingMilieux_MISCELLANEOUSOriginal ResearchIncidence (epidemiology)[ SDV.MHEP.CSC ] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemstroke3. Good healthEditorialIschemic Attack TransientRegression AnalysisFemaleepidemiologyFranceCardiology and Cardiovascular MedicineStroke incidencehospitalizationAdulttrendsmedicine.medical_specialtyacute ischemic strokeAdolescentprevalencenationwide inpatient sample03 medical and health sciencesYoung Adult[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemHumanscardiovascular diseasesSex DistributionCerebral HemorrhageIschemic Strokebusiness.industryyoungEditorialsSubarachnoid Hemorrhagemedicine.diseasetransient ischemic attackincidenceCerebrovascular Disease/Strokebusiness030217 neurology & neurosurgery
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Comparing Long-Acting Antipsychotic Discontinuation Rates Under Ordinary Clinical Circumstances: A Survival Analysis from an Observational, Pragmatic…

2021

Background Recent guidelines suggested a wider use of long-acting injectable antipsychotics (LAI) than previously, but naturalistic data on the consequences of LAI use in terms of discontinuation rates and associated factors are still sparse, making it hard for clinicians to be informed on plausible treatment courses. Objective Our objective was to assess, under real-world clinical circumstances, LAI discontinuation rates over a period of 12 months after a first prescription, reasons for discontinuation, and associated factors. Methods The STAR Network ‘Depot Study’ was a naturalistic, multicentre, observational prospective study that enrolled subjects initiating a LAI without restrictions …

MalePediatricsrespectively)0302 clinical medicineDelayed-Action PreparationBrief Psychiatric Rating ScalePharmacology (medical)he STAR Network ‘Depot Study’ prospectively followed 394 subjects initiating treatment with long-acting injections (LAIs) of antipsychotics under naturalistic conditions for 12 months. LAI discontinuation was frequent in everyday clinical practice in ItalyOriginal Research ArticleProspective StudiesProspective cohort studytreatmentMental DisordersHazard ratiowhereas more than half of participants initiating risperidone LAI and olanzapine LAI discontinued during the 12 months of follow-up (51.4 and 62.5%Psychiatric Status Rating ScaleMiddle Agedside efectsPsychiatry and Mental healthItalyMental DisorderFemalehe STAR Network ‘Depot Study’ prospectively followed 394 subjects initiating treatment with long-acting injections (LAIs) of antipsychotics under naturalistic conditions for 12 months. LAI discontinuation was frequent in everyday clinical practice in Italy occurring in almost 40% of the entire sample; side efects participant refusal to continue LAIs and LAIs no longer being required were the most frequently reported reasons for discontinuation. Paliperidone LAI and aripiprazole LAI were the least discontinued medications (33.9 and 35.4% respectively) whereas more than half of participants initiating risperidone LAI and olanzapine LAI discontinued during the 12 months of follow-up (51.4 and 62.5% respectively). In multivariate analysis being prescribed olanzapine LAI and poor medication adherence at baseline were signifcantly associated with higher discontinuation risk.HumanAntipsychotic Agentsmedicine.drugPsychopathologyAdultmedicine.medical_specialtyDiscontinuationFollow-Up StudieMedication Adherence03 medical and health sciencesmedicineHumansPaliperidoneAdverse effectSettore MED/25 - Psichiatriadiscontinuation ratesPsychiatric Status Rating Scalesrespectively). In multivariate analysisbusiness.industryLong-Acting Antipsychoticlong-acting injectable antipsychoticsSurvival AnalysisConfidence intervalparticipant refusal to continue LAIs and LAIs no longer being required were the most frequently reported reasons for discontinuation. Paliperidone LAI and aripiprazole LAI were the least discontinued medications (33.9 and 35.4%030227 psychiatryDiscontinuationProspective StudieAntipsychotic Agentoccurring in almost 40% of the entire sampleDelayed-Action PreparationsNeurology (clinical)business030217 neurology & neurosurgerybeing prescribed olanzapine LAI and poor medication adherence at baseline were signifcantly associated with higher discontinuation riskFollow-Up Studies
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The rich are different: Unravelling the perceived and self-reported personality profiles of high-net-worth individuals.

2017

Beyond money and possessions, how are the rich different from the general population? Drawing on a unique sample of high-net-worth individuals from Germany (≥1 million Euro in financial assets; N = 130), nationally representative data (N = 22,981), and an additional online panel (N = 690), we provide the first direct investigation of the stereotypically perceived and self-reported personality profiles of high-net-worth individuals. Investigating the broad personality traits of the Big Five and the more specific traits of narcissism and locus of control, we find that stereotypes about wealthy people's personality are accurate albeit somewhat exaggerated and that wealthy people can be charact…

MalePersonality Inventorymedia_common.quotation_subjectPopulation050109 social psychologySample (statistics)050105 experimental psychologyFinancial StatementsGermanyNarcissismmedicinePersonalityHumans0501 psychology and cognitive sciencesBig Five personality traitseducationGeneral Psychologymedia_commonAgededucation.field_of_studyStereotyping05 social sciencesNet worthSelf ConceptLocus of controlNarcissismFemaleSelf Reportmedicine.symptomStereotyped BehaviorPsychologySocial psychologyPersonalityBritish journal of psychology (London, England : 1953)References
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Three methods for studying developmental change: a case of reading skills and self-concept.

2002

Aims: First, to introduce and compare three statistical methods for investigating development as a cumulative process: a simplex model, latent growth curve analysis, and clustering by cases. Second, to investigate the developmental dynamics of reading skills, and self-concept of reading ability, across the first year of primary school. Sample: One hundred and five (61 boys, 44 girls) 6-to 7-year-old children from four first-grade classes in two primary schools participated in the study. Method: Children were studied three times during their first school year using an identical set of measurements: a Reading Skills Test and the Self-Concept of Ability scale. Results: A uni-construct ‘Matthew…

MalePersonality developmentmedia_common.quotation_subjecteducationSelf-conceptSample (statistics)Models PsychologicalEducationDevelopmental psychologyChild DevelopmentReading (process)Developmental and Educational PsychologyCluster AnalysisHumans0501 psychology and cognitive sciencesSet (psychology)Childmedia_common4. Education05 social sciences050301 educationSelf ConceptTest (assessment)Language developmentReadingScale (social sciences)FemalePsychology0503 education050104 developmental & child psychologyThe British journal of educational psychology
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Measurements of projected areas of seated and standing people of southern Italy based on a statistical analysis

2006

One of the most important components affecting the human thermal balance is represented by its radiative exchange with the surrounding surfaces. The projected area of the human body is an important parameter of these thermal exchanges. Unfortunately, although the anthropometric measures of people are characterized by significant differences among various populations, the experimental data currently available in the literature refers to a small group of people. Moreover, measurements are generally performed regardless of the statistical significance of the involved subjects with respect to the population to which they belong. In this study, a statistical study is introduced that is based on …

MalePosturePopulationPhysical Therapy Sports Therapy and RehabilitationHuman Factors and ErgonomicsSample (statistics)Models BiologicalWhite PeopleSocial groupStatisticsHumansBody Weights and MeasuresStatistical analysisSafety Risk Reliability and QualityeducationEngineering (miscellaneous)education.field_of_studySettore ING-IND/11 - Fisica Tecnica AmbientaleAngle factors Projected area factors Effective radiating area Thermal comfortExperimental dataAnthropometryGeographyItalyProjected areaThermodynamicsFemaleThermal balanceBody Temperature RegulationDemographyApplied Ergonomics
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Measurement Invariance of the Short Version of the Problematic Mobile Phone Use Questionnaire (PMPUQ-SV) across Eight Languages

2018

The prevalence of mobile phone use across the world has increased greatly over the past two decades. Problematic Mobile Phone Use (PMPU) has been studied in relation to public health and comprises various behaviours, including dangerous, prohibited, and dependent use. These types of problematic mobile phone behaviours are typically assessed with the short version of the Problematic Mobile Phone Use Questionnaire (PMPUQ–SV). However, to date, no study has ever examined the degree to which the PMPU scale assesses the same construct across different languages. The aims of the present study were to (i) determine an optimal factor structure for the PMPUQ–SV among university populations using eig…

MaleProblematic Mobile Phone UsePsychometricsHealth Toxicology and MutagenesisApplied psychologyPsicologia del desenvolupament[SHS.PSY]Humanities and Social Sciences/Psychology030508 substance abuselcsh:Medicinemanop: Traitement & psychologie clinique [H13] [Sciences sociales & comportementales psychologie]smartphone useGermanddc:616.890302 clinical medicineddc:150Surveys and QuestionnairesDangerous BehaviorPrevalence030212 general & internal medicineLanguageTelèfon mòbil i adolescentsEuropemeasurement invarianceScale (social sciences)languageProblematic MobileFemaleCrime0305 other medical sciencePsychologyAdultCross-Cultural ComparisonPsychometricsmobile phone useSample (statistics)Phone Use Questionnaire: Treatment & clinical psychology [H13] [Social & behavioral sciences psychology]Article03 medical and health sciencesCronbach's alphaHumansMeasurement invarianceTranslationspsychometric testingStructure InvariancePMPUQDescriptive statisticslcsh:RPublic Health Environmental and Occupational HealthProblematic Mobile Phone Use Questionnairelanguage.human_languageCell Phone UseBehavior AddictiveMobile phonemeasurement invariancFactor Analysis StatisticalInternational Journal of Environmental Research and Public Health
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Toward empirically based criteria for the classification of somatoform disorders

1999

Abstract There is a major need for an empirical evaluation of classification criteria for somatoform disorders. The present study analyzes psychometric properties of the existing criteria for somatization disorder. The full sample consisted of 324 patients seeking help because of “psychosomatic problems.” Data from a subsample of carefully diagnosed patients with somatization syndrome (n=76) and a clinical comparison group (n=32) permitted the analysis of the discriminative power of items. Twenty-one somatic symptoms adopted from DSM-IV and ICD-10 criteria did not exhibit the necessary psychometric characteristics (item probability, item-total correlation, etc.). Thirty-two somatic symptoms…

MalePsychiatric Status Rating ScalesNosologymedicine.medical_specialtyPsychometricsCultureSick RoleReproducibility of ResultsObservationMiddle Agedmedicine.diseaseFull samplePsychiatry and Mental healthClinical PsychologymedicineHumansFemaleSomatization disorderSomatoform DisordersAttributionPsychiatryPsychologySomatizationIllness behaviorClinical psychologyJournal of Psychosomatic Research
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