Search results for "SAMPLE"

showing 10 items of 2270 documents

Selective protein removal and desalting using microchip CE.

2006

Abstract This paper describes the on-line sample pretreatment and analysis of proteins and peptides with a poly(methylmethacrylate) (PMMA) microfluidic device (IonChip™). This chip consists of two hyphenated electrophoresis channels with integrated conductivity detectors. The first channel can be used for sample preconcentration and sample clean-up, while in the second channel the selected compounds are separated. Isotachophoresis (ITP) combined with zone electrophoresis (CZE) was used to preconcentrate a myoglobin sample by a factor of about 65 before injection into the second dimension and to desalt a mixture of six proteins with 100 mM NaCl. However, ITP–CZE could not be used for the rem…

chemistry.chemical_classificationChromatographyChemistryClinical BiochemistryMicrofluidicsAnalytical chemistryA proteinProteinsPeptideCell BiologyGeneral MedicineBiochemistrySample (graphics)Online SystemsAnalytical ChemistryElectrophoresis Microchipchemistry.chemical_compoundElectrophoresisMyoglobinAnimalsHumansIsotachophoresisJournal of chromatography. B, Analytical technologies in the biomedical and life sciences
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Comparison of extraction methods for polycyclic aromatic hydrocarbon determination in sediments

1990

Different sample preparation methods for the determination of polycyclic aromatic hydrocarbons (PAHs) in lake and river sediments were compared and evaluated. Freeze‐dried sediment materials were e...

chemistry.chemical_classificationChromatographyChemistryHealth Toxicology and MutagenesisEnvironmental chemistryExtraction (chemistry)Environmental ChemistryPolycyclic aromatic hydrocarbonSedimentSample preparationExtraction methodsPollutionToxicological & Environmental Chemistry
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Microwave-assisted extraction of OCPs, PCBs and PAHs concentrated by semi-permeable membrane devices (SPMDs)

2005

Abstract Microwave-assisted extraction (MAE) has been evaluated as an alternative to dialysis for extraction of some water-borne hydrophobic contaminants sampled by semi-permeable membrane devices (SPMDs). Seven organochlorine pesticides (OCPs), 11 polychlorinated biphenyls (PCBs) and 13 polycyclic aromatic hydrocarbons (PAHs) were accumulated in SPMDs at nanogram levels and extracted with three 3-min irradiation cycles with 33 mL of a solvent mixture hexane–water (10:1,v/v) in each cycle. The developed MAE method gave for all analytes investigated statistically comparable extraction yields with those found by dialysis carried out with a total volume of 250 mL hexane for 48 h at room temper…

chemistry.chemical_classificationChromatographyExtraction (chemistry)ContaminationBiochemistryAnalytical ChemistryHexaneSolventchemistry.chemical_compoundHydrocarbonchemistryEnvironmental chemistryEnvironmental ChemistrySample preparationSemipermeable membraneWater pollutionSpectroscopyAnalytica Chimica Acta
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Headspace-Liquid Phase Microextraction for Attenuated Total Reflection Infrared Determination of Volatile Organic Compounds at Trace Levels

2010

A combination of headspace (HS) sampling and liquid phase microextraction (LPME) has been successfully developed to solve sensitivity problems in attenuated total reflection (ATR) infrared determination of volatile organic compounds (VOCs). The HS sampling facilitates the selective extraction of the target volatile analytes from the sample matrix, while the liquid phase microextraction allows their preconcentration prior to infrared analysis. The direct determination of extracted analytes in the acceptor solvent provides high preconcentration factors of the order of 200 with a reduced consumption of organic solvents and a minimum generation of wastes, being thus the developed methodology a …

chemistry.chemical_classificationChromatographyExtraction (chemistry)XyleneAnalytical chemistryTolueneAnalytical ChemistrySolventchemistry.chemical_compoundchemistryAttenuated total reflectionVolatile organic compoundSample preparationBenzeneAnalytical Chemistry
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Selective solid phase extraction of a drug lead compound using molecularly imprinted polymers prepared by the target analogue approach

2002

Molecularly imprinted polymers have been evaluated at the sample clean-up stage in the analysis of a drug lead compound. In order to circumvent quantification problems related to bleeding of the template, a structurally related analogue of the latter was used. This was selected based on criteria related to interaction site location, solubility, availability and stability of the analogue. Selection of suitable polymerisation conditions was then made using a small batch format (ca. 50 mg) and rapid assessment of binding in the equilibrium mode. It was found that the amount of template could be greatly reduced compared to the conventional protocol, requiring only 5 μmol of template per gram of…

chemistry.chemical_classificationChromatographyOrganic ChemistryClinical BiochemistryMolecularly imprinted polymerPolymerBiochemistryAnalytical Chemistrychemistry.chemical_compoundPhotopolymerchemistrySample preparationSolid phase extractionSolubilityMolecular imprintingLead compoundChromatographia
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Inductively coupled plasma atomic emission spectrometric determination of arsenic in mussel products

1993

A precise, accurate procedure is proposed for the determination of arsenic in mussel products by inductively coupled plasma atomic emission spectrometry. Organic matter is destroyed by dry ashing. Experimental conditions for the determination of arsenic were selected and an interference study was carried out. The methodology developed has a detection limit of 0.1 μg g−1, a relative standard deviation of 3%, and a recovery percentage of 98±2%. The accuracy of the method was checked by analysis of a certified sample of NIST oyster tissue (certified 14.0±1.2 μg g−1; found 14.1±1.1 μg g−1). The proposed procedure was used to analyze real samples of mussel products.

chemistry.chemical_classificationDetection limitChromatographyAtomic emission spectroscopychemistry.chemical_elementMusselBiochemistryAnalytical ChemistrychemistryAshingSample preparationOrganic matterInductively coupled plasmaArsenicFresenius' Journal of Analytical Chemistry
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In-tube solid-phase microextraction coupled by in valve mode to capillary LC-DAD: Improving detectability to multiresidue organic pollutants analysis…

2009

Abstract A simple and fast capillary chromatographic method has been developed to identify and quantify organic pollutants at sub-ppb levels in real water samples. The major groups of pesticides (organic halogens, organic phosphorous, and organic nitrogen compounds), some hydrocarbons (polycyclic aromatic hydrocarbons), phthalates and some phenols such as phenol and bisphenol A (endocrine disruptors) were included in this study. The procedure was based on coupling, in-tube solid-phase microextraction (IT-SPME) by using a conventional GC capillary column (95% methyl–5% phenyl substituted backbone, 80 cm × 0.32 mm i.d., 3 μm film thickness) in the injection valve to capillary liquid chromatog…

chemistry.chemical_classificationDetection limitChromatographyChemistryCapillary actionOrganic ChemistryAnalytical chemistryGeneral MedicineReversed-phase chromatographySolid-phase microextractionSensitivity and SpecificityBiochemistryHigh-performance liquid chromatographyAnalytical ChemistryHydrocarbonSeawaterSample preparationPolycyclic HydrocarbonsLasers SemiconductorOrganic ChemicalsSolid Phase MicroextractionWater Pollutants ChemicalChromatography LiquidJournal of Chromatography A
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Indirect analysis of urea herbicides from environmental water using solid-phase microextraction.

2000

We described here a solid-phase microextraction procedure used to extract six urea pesticides-- chlorsulfuron, fluometuron, isoproturon, linuron, metobromuron and monuron--from environmental samples. Two polydimethylsiloxanes and a polyacrylate fiber (PA) are compared. The extraction time, pH control, addition of NaCl to the water and the influence of organic matter such as humic acid on extraction efficiency were examined to achieve a sensitive method. Determination was carried out by gas chromatography with nitrogen-phosphorus detection. The proposed method requires the extraction of 2 ml of sample (pH 4, 14.3%, w/v, NaCl) for 60 min with the PA fiber. The limits of detection range from 0…

chemistry.chemical_classificationDetection limitChromatographyFluometuronHerbicidesPhenylurea CompoundsOrganic ChemistryReproducibility of ResultsGeneral MedicineSolid-phase microextractionBiochemistrySensitivity and SpecificityAnalytical Chemistrychemistry.chemical_compoundchemistryHumic acidOrganic matterSample preparationSolid phase extractionGas chromatographyWater Pollutants ChemicalJournal of chromatography. A
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CHEMICAL ANALYSIS FOR SPECIFIC COMPONENTS | Micronutrients and Other Minor Meat Components

2014

The chemical analysis of the many micronutrients (minerals and vitamins) and other components such as cholesterol and enzymes in meat and meat products are addressed in this article. The sample preparation and main methods for the determination of these components are reviewed and described as well as their respective major advantages and disadvantages.

chemistry.chemical_classificationEnzymeFat-Soluble VitaminBiochemistrychemistryfood and beveragesWater-Soluble VitaminSample preparationFood scienceMicronutrient
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Macroscopic persistent currents in YBa2Cu3O7

1988

Persistent currents in polycrystalline YBa2Cu3O7 rings have been investigated by measuring the spatial distribution of the magnetic flux trapped in field-cooled samples. The results unambiguously show that macroscopic persistent ring currents exist. The critical current density depends very sensitively on the sample quality, reachingj c ≈250 A/cm2 at 77 K for our best samples.

chemistry.chemical_classificationMaterials scienceHigh-temperature superconductivityCondensed matter physicspacs:68.35.JaPersistent currentCondensed Matter PhysicsRing (chemistry)Magnetic fluxElectronic Optical and Magnetic Materialslaw.inventionSample qualitychemistrypacs:67.70.+nlawCondensed Matter::Superconductivityddc:530General Materials ScienceCrystalliteCritical currentpacs:61.12.ExInorganic compoundZeitschrift f�r Physik B Condensed Matter
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