Search results for "SAMPLE"

showing 10 items of 2270 documents

Assessment of the Inter-Batch Variability of Microstructure Parameters in Topical Semisolids and Impact on the Demonstration of Equivalence

2019

Demonstration of similar microstructure is essential for demonstrating the equivalence of generic topical products since the microstructure of semisolids may affect the drug release. The objective of this study was to compare the microstructure-defining physical parameters of different batches of a reference ointment containing calcipotriol and betamethasone (Daivobet 50 &micro

microstructureequivalencelcsh:RS1-441Pharmaceutical Sciencegeneric semisolid formulation02 engineering and technology030226 pharmacology & pharmacyDosage formArticlelcsh:Pharmacy and materia medica03 medical and health sciences0302 clinical medicinetopical drugStatisticsinter-batch variabilityEquivalence (measure theory)Parametric statisticsMathematics021001 nanoscience & nanotechnologyMicrostructureConfidence intervalReference productSample size determinationDrug releaserheology0210 nano-technologyPharmaceutics
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Orthogonal switching of AMS axes during type-2 fold interference : Insights from integrated X-ray computed tomography, AMS and 3D petrography

2017

We applied X-ray computed microtomography (μ-CT) in combination with anisotropy of magnetic susceptibility (AMS) analysis to study metamorphic rock fabrics in an oriented drill core sample of pyrite-pyrrhotite-quartz-mica schist. The sample is extracted from the Paleoproterozoic Martimo metasedimentary belt of northern Finland. The μ-CT resolves the spatial distribution, shape and orientation of 25,920 pyrrhotite and 153 pyrite grains localized in mm-thick metapelitic laminae. Together with microstructural analysis, the μ-CT allows us to interpret the prolate symmetry of the AMS ellipsoid and its relationship to the deformation history. AMS of the sample is controlled by pyrrhotite porphyro…

microtomography010504 meteorology & atmospheric sciencesMetamorphic rockMineralogyCore sampleengineering.material010502 geochemistry & geophysics01 natural sciencesstrainAMSAnisotropyPyrrhotite0105 earth and related environmental sciencesrasitusta114SchistGeologyFold (geology)Ellipsoidmagnetic fabricpyrrhotiteengineeringmicrotectonicsGeologyPrincipal axis theorem
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Differentiation among dairy products by combination of fast field cycling NMR relaxometry data and chemometrics

2021

A set of commercial milk and Sicilian cheeses was analysed by a combination of fast field cycling (FFC) nuclear magnetic resonance (NMR) relaxometry and chemometrics. The NMR dispersion (NMRD) curves were successfully analysed with a mathematical model applied on Parmigiano-Reggiano (PR) cheese. Regression parameters were led back to the molecular components of cheeses (water trapped in casein micelles, proteins and fats) and milk samples (water belonging to hydration shells around dispersed colloidal particles of different sizes and bulk water). The application of chemometric analysis on relaxometric data enabled differentiating milk from cheeses and revealing differences within the two sa…

milkRelaxometryMagnetic Resonance SpectroscopyChromatographyField cyclingdairy productsChemistryrelaxometryGeneral ChemistryBulk waterchemometricsMagnetic Resonance ImagingCasein micellescheeseChemometricsFFC NMRColloidal particleAnimalsGeneral Materials ScienceStatistical analysisTwo sampleMagnetic Resonance in Chemistry
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A new approach to calibrate the thermal conditions in space charge measurements on HVDC mini-cables

2019

The PEA method is currently widespread used for space charge measurements in mini-cables in order to qualify the behavior of semicon-dielectric-semicon compound under electric and thermal stress. The main goal of this research is to quantitatively evaluate the relationship between the thermal boundary conditions applied to cables or mini-cables and the maximum local electric field due to the accumulated space charge. Hitherto, several research groups have obtained thermal gradients over the dielectric's radius heating the conductor by Joule effect due to an induced current. In this paper, a numerical approach is offered to calibrate the heat exchange boundary conditions to apply to a sample…

mini-cable sample010302 applied physicsMaterials sciencePEA method020209 energyJoule effect02 engineering and technologyMechanicsDielectric01 natural sciencesSpace chargeSpace chargeConductorSettore ING-IND/31 - ElettrotecnicaElectric field0103 physical sciencesThermal0202 electrical engineering electronic engineering information engineeringthermal gradientBoundary value problemElectrical conductorHVDC cable2019 IEEE Conference on Electrical Insulation and Dielectric Phenomena (CEIDP)
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Pokémon GO 2016: Exploring Situational Contexts of Critical Incidents in Augmented Reality

2016

Pokémon GO, an augmented reality mobile game, captured the attention of millions of people around the world in July 2016. Various sources from around the globe have reported both positive and negative incidents and outcomes related to the game. Some of the incidents have been particularly remarkable for the player, i.e., critical incidents. A critical incident is a single experience, which a person perceives or remembers as unusually positive or negative. Critical incidents typically are highly influential for human behaviour, and thus, important to study. Playing augmented reality games can take place in varying situational contexts. Situational context includes information that can be use…

mobile gamingvuorovaikutusInternet privacyGlobeinteraction050801 communication & media studiesContext (language use)Sample (statistics)critical incidentsMetaversepaikkacontexts0508 media and communicationssituational contextplace0502 economics and businessmedicineSituational ethicslisätty todellisuusSocialityta113Pokemon GObusiness.industry05 social sciencessosiaalisuussocialityexergamingObject (philosophy)mobile gameaugmented realitymedicine.anatomical_structurereasons050211 marketingAugmented realitybusinessPsychologySocial psychologyJournal of Virtual Worlds Research
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Ecologists overestimate the importance of predictor variables in model averaging: a plea for cautious interpretations.

2014

Abstract: Information-theory procedures are powerful tools for multimodel inference and are now standard methods in ecology. When performing model averaging on a given set of models, the importance of a predictor variable is commonly estimated by summing the weights of models where the variable appears, the so-called sum of weights (SW). However, SWs have received little methodological attention and are frequently misinterpreted. We assessed the reliability of SW by performing model selection and averaging on simulated data sets including variables strongly and weakly correlated to the response variable and a variable unrelated to the response. Our aim was to investigate how useful SWs are …

model selectionInformation theorymultimodel inferenceBayesian information criterionStatisticsEconometricsRange (statistics)Akaike Information Criterion[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/Symbiosisbaseline sum of weightsSet (psychology)BiologyEcology Evolution Behavior and SystematicsMathematicsinformation theory[STAT.AP]Statistics [stat]/Applications [stat.AP]Ecological ModelingModel selection[ STAT.AP ] Statistics [stat]/Applications [stat.AP]model averagingBayesian information criterionChemistryVariable (computer science)Sample size determinationvariable importanceAkaike information criterion[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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Pain and clinical findings in the low back: a study of industrial employees with 5-, 10-, and 28-year follow-ups.

2009

Little is known about the relationships of clinical findings in the low back with low back pain (LBP) in the normal working population. We studied whether physiotherapist's findings in the low back were associated with local and radiating LBP among a cohort (n=902) of employees in the engineering industry. A systematic non-proportional sample was drawn in strata by age, gender, and occupational class. The non-proportionality aimed at increasing sample size in smaller strata. Physiotherapists performed the straight-leg raising test (SRL), and made assessments of the fingertip-to-floor distance and pain in palpation of the lumbar interspinous spaces. The variables on pain at the interspinous …

musculoskeletal diseasesAdultMalemedicine.medical_specialtyLogistic regressionSeverity of Illness IndexPhysical medicine and rehabilitationhealth services administrationSeverity of illnessmedicineCluster AnalysisHumansGeneralizability theoryProspective StudiesProspective cohort studyWorkplaceReferred painbusiness.industryMiddle AgedLow back painHealth Surveysbody regionsAnesthesiology and Pain MedicineLogistic ModelsSample size determinationCohortPhysical therapypopulation characteristicsFemalemedicine.symptombusinessLow Back PainFollow-Up StudiesEuropean journal of pain (London, England)
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Effects of responsible human resource management practices on female employees’ turnover intentions

2017

This study focuses on the effects of socially responsible human resource management (SR-HRM) practices on female employees’ turnover intentions and the moderating effect of supervisor gender on this relationship. With a sample of 212 female employees from eight different industries in Finland, the results indicate that SR-HRM practices promoting equal career opportunities and work–family integration play a significant role in reducing women's turnover intentions. The study adds to the academic discourse of corporate social responsibility by highlighting the impact of the organizational-level HRM determinants on the individual-level outcome. In addition, supervisor gender makes a difference …

naisetEconomics and EconometricsSupervisorComputingMilieux_THECOMPUTINGPROFESSIONeducation05 social sciencesSample (statistics)06 humanities and the arts0603 philosophy ethics and religionhenkilöstöjohtaminenhuman resource managementfemale employeesHuman resource managementtyöntekijät0502 economics and businessCorporate social responsibility060301 applied ethicsBusiness and International ManagementPsychologyta512Social psychologySocial responsibility050203 business & managementBusiness Ethics: A European Review
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Early Career Women in Academia: An Exploration of Networking Perceptions

2016

This chapter explores women’s networking perceptions by focusing on early career women in social sciences. Within an exploratory research design it asks how early career women define the early career stage in academia, what definitions, meanings and interpretations they give for networks and networking, how they construct the networking process and their ability to establish and/or join networks, as early career researchers and as women. Based on two group interviews with 12 participants, our findings show that early career women in academia favour networking with peers based on shared interests (organic networking). At the same time though, they challenge and step over the perceived gender…

naisetKnowledge managementHigher educationmedia_common.quotation_subjectverkostoituminennetworkingExploratory researchyhteiskuntatieteetSample (statistics)academia050905 science studiesCompliance (psychology)PerceptionPolitical sciencekorkeakoulutmedia_commonverkostotComputingMilieux_THECOMPUTINGPROFESSIONbusiness.industry05 social sciences050301 educationPublic relationsnetworks0509 other social sciencesbusinessConstruct (philosophy)0503 educationNexus (standard)career womenSocial capital
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Modification of a commercial atomic force microscopy for low-noise, high-resolution frequency-modulation imaging in liquid environment.

2011

A key issue for high-resolution frequency-modulation atomic force microscopy imaging in liquids is minimizing the frequency noise, which requires a detailed analysis of the corresponding noise contributions. In this paper, we present a detailed description for modifying a commercial atomic force microscope (Bruker MultiMode V with Nanoscope V controller), aiming at atomic-resolution frequency-modulation imaging in ambient and in liquid environment. Care was taken to maintain the AFMs original stability and ease of operation. The new system builds upon an optimized light source, a new photodiode and an entirely new amplifier. Moreover, we introduce a home-built liquid cell and sample holder …

noiseMaterials scienceoptical sensorsAtomic force acoustic microscopy530Noise (electronics)law.inventionOpticsphotodiodeslawInstrumentationAtomic de Broglie microscopeatomic force microscopycalcium compoundsbusiness.industrysample holdersAmplifierNoise spectral densityPhotodiodefrequency modulationmodulationfrequencyamplifiersbusinessNon-contact atomic force microscopyFrequency modulationimage resolutionThe Review of scientific instruments
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