Search results for "SAP"

Communication quality and added value: a measurement instrument for municipalities

2009

PurposeThis study aims to achieve a better understanding of communication quality and how it can be measured in the municipal context. A previously developed instrument for measuring communication in municipalities is tested and evaluated.Design/methodology/approachThe instrument draws on the balanced scorecard of Kaplan and Norton and quality control procedures as utilised by the European Foundation of Quality Measurement (EFQM). For municipalities, communication quality can be defined as the degree to which communication contributes towards the effectiveness of municipal policy and how it strengthens the relationship between citizens and municipal organisations. Three communication functi…

Initial training and professionalization process of volunteer firefighters

2023

The aim of this research is to contribute to a better understanding of the initial training of volunteer firefighters, with a particular focus on the process of appropriation of this training, the process of professionalization and the obstacles encountered by this population.Using a mixed-methods approach, 330 volunteer firefighters still in service were interviewed by questionnaire as part of a longitudinal survey, while 42 individuals who had ended their involvement during their initial training were consulted by means of semi-structured interviews. Sixteen direct observation sessions supplemented the data collection.Firstly, several types of appropriation of initial training have been h…

Calcitonin gene-related peptide partly protects cultured smooth muscle cells from apoptosis induced by an oxidative stress via activation of ERK1/2 M…

2003

Abstract Oxidative stress induced by a glucose/glucose oxidase (G/GO) generator system dose-dependently decreased the viability of cultured vascular smooth muscle cells (VSMC) as estimated by MTT assay. Cell death was induced in 40% of cells exposed to 0.2 IU/ml of the free radical generating mixture. Annexin-V labeling, Hoechst staining together with DNA laddering demonstrated that apoptosis was responsible for this cell loss. Pretreatment of the cells with 10−8 M calcitonin gene-related peptide (CGRP) significantly attenuated the damaging effect of the oxidative stress. Indeed, cell viability was estimated to be 80% in CGRP-treated group, instead of 60% in absence of CGRP treatment. This …

El incendio del palacio de Mosen Sorell de Valencia en 1878 y su repercusión urbanística

2010

En 1878 un pavoroso incendio destruyó gran parte del palacio de Mosén Sorell, una de las mejores casas señoriales de la Valencia del siglo XV, del que tres portadas subsisten fuera de su original emplazamiento. Al año siguiente del incendio se propuso el ensanche de la plaza donde se levantaba dicho palacio, a costa de una sustanciosa porción de su superficie. El arquitecto Vicente Constantino Marzo efectuó el proyecto, que fue respaldado por un real decreto tras la demanda contra aquél de varios interesados propietarios. El presente artículo desvela los pormenores de este proceso. (A)

La capilla de la Facultad de Filosofía y Letras de la Universidad de Valencia

1986

Relaxant and antiadrenergic effects of ranolazine in human saphenous vein.

2019

Abstract OBJECTIVES Ranolazine improves vascular function in animal models. We evaluate the effects of ranolazine on vascular function and adrenergic response in human saphenous vein. METHODS Rings from 53 patients undergoing coronary artery bypass grafting were mounted in organ baths. Concentration–response curves to ranolazine were constructed in rings precontracted with phenylephrine, endothelin-1, vasopressin, KCl and the thromboxane A2 analogue U-46619. In rings precontracted with phenylephrine, relaxation to ranolazine was tested in the absence and presence of endothelial factors inhibitors, K+ channel blockers and verapamil. The effects of ranolazine on frequency–response and concent…

Impacto del ozono troposférico sobre la anatomía foliar de Abies pinsapo Boiss. I.: Estudio de la distribución de daños

2009

RESUMEN. Impacto del ozono troposférico sobre la anatomía foliar de Abies pinsapo Boiss. I: Estudio de la distribución de daños. Con el fin de elaborar unos criterios unificados para la evaluación del impacto del ozono troposférico y compararlos con la respuesta de las poblaciones naturales de Sierra Bermeja y Sierra de las Nieves, se han reproducido en cámaras Open Top, ambientes filtrados y enriquecidos con ozono para realizar una caracterización microscópica del daño que produce el ozono troposférico sobre Abies pinsapo Boiss. Los resultados demuestran que pese a que la morfología foliar permanece inalterada tras someter durante un mes en condiciones de 30 ppb durante 8 horas al día, a n…

External reinforcement of varicose veins with PTFE prosthesis in infrainguinal bypass surgery -- clinical results.

2003

OBJECTIVE Segmental varicose degeneration of the autogenous greater saphenous vein may limit its use in infrainguinal bypass surgery. Wrapping a PTFE prosthesis around dilated veins has emerged as an option to create externally reinforced vein bypasses. Results regarding graft patency and limb salvage were analyzed. METHODS Between September 1995 and January 2001, 35 infrainguinal bypass operations in 33 patients were performed with greater saphenous veins exhibiting segmental varicose dilatation. Grafts were followed by duplex scan and retrospective analysis of graft patency and limb salvage was performed. RESULTS One bypass prompted successful revision for early occlusion. Four bypasses r…

Neutrophil Adherence to Activated Saphenous Vein and Mammary Endothelium After Graft Preparation

2005

Interaction of circulating leukocytes and vascular endothelium plays an important role in vasoconstriction, endothelial dysfunction, and vascular injury. Dilation procedures of grafts before coronary artery bypass graft surgery might lead to vascular injury and subsequent bypass graft disease.We analyzed in vitro the adherence of fluorescence-labeled polymorphonuclear neutrophils (PMNs) to endothelium of human saphenous vein grafts or internal mammary artery grafts after stimulation with thrombin (0.5 to 2 U/mL) or dilating procedures. Furthermore, we investigated endothelial function of prepared grafts.Thrombin stimulation resulted in a dose-dependent increase of PMN adherence to the endot…

Conflicting coccolithophore and geochemical evidence for productivity levels in the Eastern Mediterranean sapropel S1

2011

Abstract The cyclic development of anoxic conditions in the eastern Mediterranean deep sea waters is one of the most fascinating research topics in paleoceanographic studies. In combination with bottom water stagnation, enhanced primary production is a common explanation for the deposition of organic-rich layers (sapropels). This is supported by extensive evidence from both geochemical and micropaleontological studies. The correspondence of recent sapropel layers with peaks of the lower photic zone coccolithophore species Florisphaera profunda has been interpreted as a proxy for the development of a deep chlorophyll maximum (DCM), due to the pycnocline/nutricline shallowing into the lower p…