Search results for "SCALE"
showing 10 items of 5180 documents
Absolute quantification of noncoding RNA by microscale thermophoresis
2019
Abstract Accurate quantification of the copy numbers of noncoding RNA has recently emerged as an urgent problem, with impact on fields such as RNA modification research, tissue differentiation, and others. Herein, we present a hybridization‐based approach that uses microscale thermophoresis (MST) as a very fast and highly precise readout to quantify, for example, single tRNA species with a turnaround time of about one hour. We developed MST to quantify the effect of tRNA toxins and of heat stress and RNA modification on single tRNA species. A comparative analysis also revealed significant differences to RNA‐Seq‐based quantification approaches, strongly suggesting a bias due to tRNA modifica…
Accuracy, Coherence, and Discrepancy in Self and Other Reports: Moving Toward an Interactive Perspective of Organizational Dissent.
2013
The purpose of this study was twofold and involved examining the viability of using the Organizational Dissent Scale as an other-report instrument, and developing additional perceptual data related to dissent expression. A sample of 291 people completed survey questionnaire measures of organizational dissent. Equal-sized groups ( n = 97) completed either a self-report, a workplace colleague other-report, or an organizational outsider other-report. Results indicated the Organizational Dissent Scale performed reliably as an other-report, but it showed some tendency for social desirability. In addition, findings suggested that certain indicators of proximity to the dissenter reduced discrepan…
Interface Detection Using a Quenched-Noise Version of the Edwards-Wilkinson Equation
2015
We report here a multipurpose dynamic-interface-based segmentation tool, suitable for segmenting planar, cylindrical, and spherical surfaces in 3D. The method is fast enough to be used conveniently even for large images. Its implementation is straightforward and can be easily realized in many environments. Its memory consumption is low, and the set of parameters is small and easy to understand. The method is based on the Edwards-Wilkinson equation, which is traditionally used to model the equilibrium fluctuations of a propagating interface under the influence of temporally and spatially varying noise. We report here an adaptation of this equation into multidimensional image segmentation, an…
Automatic dynamic texture segmentation using local descriptors and optical flow
2012
A dynamic texture (DT) is an extension of the texture to the temporal domain. How to segment a DT is a challenging problem. In this paper, we address the problem of segmenting a DT into disjoint regions. A DT might be different from its spatial mode (i.e., appearance) and/or temporal mode (i.e., motion field). To this end, we develop a framework based on the appearance and motion modes. For the appearance mode, we use a new local spatial texture descriptor to describe the spatial mode of the DT; for the motion mode, we use the optical flow and the local temporal texture descriptor to represent the temporal variations of the DT. In addition, for the optical flow, we use the histogram of orie…
Lattice Boltzmann Simulations at Petascale on Multi-GPU Systems with Asynchronous Data Transfer and Strictly Enforced Memory Read Alignment
2015
The lattice Boltzmann method is a well-established numerical approach for complex fluid flow simulations. Recently general-purpose graphics processing units have become accessible as high-performance computing resources at large-scale. We report on implementing a lattice Boltzmann solver for multi-GPU systems that achieves 0.69 PFLOPS performance on 16384 GPUs. In addition to optimizing the data layout on the GPUs and eliminating the halo sites, we make use of the possibility to overlap data transfer between the host CPU and the device GPU with computing on the GPU. We simulate flow in porous media and measure both strong and weak scaling performance with the emphasis being on a large scale…
Fractal dynamics in chaotic quantum transport
2013
Despite several experiments on chaotic quantum transport in two-dimensional systems such as semiconductor quantum dots, corresponding quantum simulations within a real-space model have been out of reach so far. Here we carry out quantum transport calculations in real space and real time for a two-dimensional stadium cavity that shows chaotic dynamics. By applying a large set of magnetic fields we obtain a complete picture of magnetoconductance that indicates fractal scaling. In the calculations of the fractality we use detrended fluctuation analysis -- a widely used method in time series analysis -- and show its usefulness in the interpretation of the conductance curves. Comparison with a s…
Government policy failure in public support for research and development
2014
peer-reviewed Promoting Research and Development (R&D) and innovative activity is a key element of the EU Lisbon Agenda and is seen as playing a central part in stimulating economic development. In this paper we argue that, even allowing for benevolent policy-makers, informational asymmetries can lead to a misallocation of public support for R&D, hence government policy failure, with the potential to exacerbate preexisting market failures. Initially, we explore alternative allocation mechanisms for public support, which can help to minimize the scale of these government policy failures. Of these mechanisms (grants, tax credits, or allocation rules based on past performance), our results sug…
Gender segregation in the employment of higher education graduates
2014
This article examines the employment and placement in the working life of Finnish higher education graduates (i.e. graduates from universities and polytechnics), focusing on gender equality. It reports a study on gender segregation in higher education and working life, considered in relation to Nordic gender equality policies. The data were gathered via a questionnaire administered to graduates in business and administration (n = 1067) and in technology (n = 1087), three years after their graduation. The results showed that men were able to secure permanent and full-time employment more often than women, and men achieved better correspondence between their degree and their employment. Howev…
Influencia del docente y la docente, la metodología y el contenido de las clases de educación física en la percepción de estudiantado chileno
2021
Resumen Introducción. La relevancia de la educación en la sociedad actual es evidente, por ello, es de vital importancia conocer la percepción de los diversos actores que interactúan en esta, en particular, la del estudiantado sobre las metodologías y contenidos que ofrece el profesorado es determinante en el proceso de enseñanza-aprendizaje. Objetivo. Conocer la percepción que reportan estudiantes de tres centros educativos de la región de Valparaíso (Chile), en relación con la satisfacción por las actividades deportivas, la clase de educación física y la función del personal docente. Metodología. Se utilizó una escala de 12 ítems agrupadas en tres dimensiones. Se aplicó una escala de perc…
MOCSE Centered on Students: Validation of Learning Demands and Teacher Support Scales
2020
Based on The Educational Situation Quality Model (MOCSE, acronym in Spanish) framework, the primary objective of this study is to test the factorial validity and reliability of two MOCSE measure instruments referred to the preactional-decisional phase, specifically to learning demands and teacher supports perceived by students to overcome such demands in the classroom context. The participants were 357 Spanish undergraduate students. The data obtained by exploratory and confirmatory factor analyses revealed that the “Learning Demands Scale” (MOCSE-LDS) has a two-factor structure: perceived desirability and feasibility of demands. The data also revealed that the “Teacher Support Questionnair…