Search results for "SECR"
showing 10 items of 1169 documents
Modifications of atrial natriuretic peptide and vasopressin peptides in the rat hypothalamic supraoptic nucleus during resistance training
2010
Many studies have demonstrated the involvement of atrial natriuretic peptide (ANP) and vasopressin (VP) in the homeostasis of body fluids, but few studies have regarded the hypothalamic magnocellular neurosecretory system during physical exercises. The aim of the present immunohistochemical work is to study the activity of ANP and VP secreting neurons of the hypothalamic supraoptic nucleus during and after resistance training. The study was carried out in Wistar rats trained by a physical resistance-type exercise, using a rung ladder and a varying load fastened to the tail of each rat; the exercise lasted 20 min everyday for periods of 15, 30 and 45 days. Animal groups were sacrificed at th…
Salivary gland proteins alterations in the diabetic milieu
2021
AbstractSalivary glands are considered the chief exocrine glands of the mouth and physiologically contribute to the maintenance of the homeostasis of the oral cavity. They consist of the parotid, submandibular and sublingual glands, which come in pairs and are collectively called the major glands, and the minor glands, which are much smaller and are dispersed throughout the buccal cavity. Salivary glands are distinguished by their size, amount of saliva secretion and their location in the oral cavity. Salivary glands pathophysiology has been a subject of interest in various worldwide metabolic disorders, including diabetes mellitus. Diabetes mellitus (DM), a global health concern, with a pa…
Wharton’s Jelly Mesenchymal Stromal Cells Support the Expansion of Cord Blood–derived CD34+Cells Mimicking a Hematopoietic Niche in a Direct Cell–cel…
2018
Wharton’s jelly mesenchymal stromal cells (WJ-MSCs) have been recently exploited as a feeder layer in coculture systems to expand umbilical cord blood–hematopoietic stem/progenitor cells (UCB-HSPCs). Here, we investigated the role of WJ-MSCs in supporting ex vivo UCB-HSPC expansion either when cultured in direct contact (DC) with WJ-MSCs or separated by a transwell system or in the presence of WJ-MSC–conditioned medium. We found, in short-term culture, a greater degree of expansion of UCB-CD34+cells in a DC system (15.7 ± 4.1-fold increase) with respect to the other conditions. Moreover, in DC, we evidenced two different CD34+cell populations (one floating and one adherent to WJ-MSCs) with …
Atrial Natriuretic Peptide presence in parotid gland of human fetus at 13th week of development and in adult man
2013
Our immunohistochemical study shows that atrial natriuretic peptide (ANP) is present in both human fetal and adult parotid gland. In the fetuses ANP is localized in cell clusters, while in adult parotid gland, the ANP is seen only in the wall of intra- and extralobular ducts. The results suggest that ANP might play a role in the differentiation of the parotid gland similarly as in brain and that during fetal growth ANP may play a role in the regulating the secretion of primitive salivary fluid, even if acini are still not developed. (Folia Histochemica et Cytobiologica 2013, Vol. 51, No. 1, 55-58)
SecureBallot: A secure open source e-Voting system
2021
Abstract Voting is one of the most important acts through which a community can make a collective decision. In recent years, many works have focused on improving traditional voting mechanisms and, as a result, a wide range of electronic voting (e-Voting) systems have been proposed. Even though some approaches have achieved a proper level of usability, the main challenges of e-Voting are essentially still open: protect the privacy of participants, guarantee secrecy, anonymity, integrity, uniqueness, and authenticity of votes, while making e-Voting as trustful as voting. In order to address this issue, we present SecureBallot, a secure open-source e-Voting system that completely decouples the…
Seroprevalence of Norovirus Genogroup IV Antibodies among Humans, Italy, 2010–2011
2014
Antibodies specific to genogroup IV identified in human specimens suggest zoonotic exposure.
Identification of the novel Kawasaki 2014 GII.17 human norovirus strain in Italy, 2015
2015
Surveillance of noroviruses in Italy identified the novel GII.17 human norovirus strain, Kawasaki 2014, in February 2015. This novel strain emerged as a major cause of gastroenteritis in Asia during 2014/15, replacing the pandemic GII.4 norovirus strain Sydney 2012, but being reported only sporadically elsewhere. This novel strain is undergoing fast diversification and continuous monitoring is important to understand the evolution of noroviruses and to implement the future strategies on norovirus vaccines.
FISIOPATOLOGIA DELLA SINTESI DELLE LIPOPROTEINE INTESTINALI
2015
La sintesi di lipoproteine di origine intestinale è un processo sequenziale, necessario per l’assorbimento dei lipidi e delle vitamine liposolubili di origine alimentare. L’assemblaggio dei chilomicroni inizia nel reticolo endoplasmico con la formazione di particelle ricche di fosfolipidi che sono poi trasportate al Golgi per essere secrete. Diverse classi di trasportatori giocano un ruolo sia nell’assorbimento selettivo che nel trasporto di lipidi attraverso i villi intestinali. Una volta secrete nel circolo linfatico, le lipoproteine ricche di trigliceridi (LRT) sono sottoposte all’azione della Lipasi Lipoproteica (LPL), che catalizza l’idrolisi dei triacilgliceroli delle lipoproteine a d…
Secrecy analysis and learning-based optimization of cooperative NOMA SWIPT systems
2019
Non-orthogonal multiple access (NOMA) is considered to be one of the best candidates for future networks due to its ability to serve multiple users using the same resource block. Although early studies have focused on transmission reliability and energy efficiency, recent works are considering cooperation among the nodes. The cooperative NOMA techniques allow the user with a better channel (near user) to act as a relay between the source and the user experiencing poor channel (far user). This paper considers the link security aspect of energy harvesting cooperative NOMA users. In particular, the near user applies the decode-and-forward (DF) protocol for relaying the message of the source no…
Apical transport of osteopontin is independent of N-glycosylation and sialylation.
2002
Studies of how epithelial surface polarity into apical and basolateral domains is generated and maintained have proposed that carbohydrate modifications serve as apical targeting signals for proteins by interacting with lectin sorters. However, the experimental evidence in support of N-glycans, O-glycans and sialic acids mediating apical transport is still very controversial. This could be partly due to the fact that in most studies exogenously expressed proteins were analysed. One has, therefore, examined the role of carbohydrate moieties in apical targeting of the endogenous secretory protein osteopontin in MDCK cells. It was found, however, that sorting of osteopontin does not require N-…