6533b7d4fe1ef96bd1261df3

RESEARCH PRODUCT

Atrial Natriuretic Peptide presence in parotid gland of human fetus at 13th week of development and in adult man

Aldo GerbinoElvira Vittoria FarinaMaria BuscemiLuana Lipari

subject

Settore BIO/17 - IstologiaAdultMalemedicine.medical_specialtyHistologyGestational AgePeptide hormonePathology and Forensic MedicineFetusstomatognathic systemAtrial natriuretic peptideANPhuman parotid glandontogenyInternal medicineinglesemedicineAcinar cellHumansParotid GlandSecretionFetusSettore BIO/16 - Anatomia Umanabusiness.industryGeneral MedicineParotid glandmedicine.anatomical_structureEndocrinologyHuman fetalcardiovascular systemImmunohistochemistrybusinessAtrial Natriuretic Factorhormones hormone substitutes and hormone antagonistscirculatory and respiratory physiology

description

Our immunohistochemical study shows that atrial natriuretic peptide (ANP) is present in both human fetal and adult parotid gland. In the fetuses ANP is localized in cell clusters, while in adult parotid gland, the ANP is seen only in the wall of intra- and extralobular ducts. The results suggest that ANP might play a role in the differentiation of the parotid gland similarly as in brain and that during fetal growth ANP may play a role in the regulating the secretion of primitive salivary fluid, even if acini are still not developed. (Folia Histochemica et Cytobiologica 2013, Vol. 51, No. 1, 55-58)

https://doi.org/10.5603/fhc.2013.008