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showing 10 items of 2059 documents

Histopathological comparison of healing after maxillary sinus augmentation using xenograft mixed with autogenous bone versus allograft mixed with aut…

2018

To compare the clinical and histologic outcomes of two different grafting materials (allograft and xenograft) when combined with autogenous bone and covered with a collagen membrane for sinus augmentation. MATERIAL AND METHODS: A parallel case series of fourteen patients in need of a unilateral sinus augmentation was evaluated in this study. Seven patients received a graft composed by autologous cortical bone (ACB) and anorganic bovine bone in a ratio of 1:1; the other seven patients received ACB mixed with an allograft in the same ratio. Bone biopsies were obtained 6 months after sinus augmentation at the time of implant placement. Comparative histomorphometrical, histopathological, and im…

0301 basic medicineMalemedicine.medical_specialtySinus Floor AugmentationStromal cellMaxillary sinusSinus Floor AugmentationOdontología03 medical and health sciences0302 clinical medicineAlveolar ProcessMedicineAnimalsHumansSinus (anatomy)AgedBone Transplantationbusiness.industryOsteoidAlveolar processMesenchymal stem cellDental Implantation Endosseous030206 dentistryMiddle AgedAllograftsSurgery030104 developmental biologymedicine.anatomical_structureHeterograftsCortical boneCattleFemaleOral SurgerybusinessClinical oral implants research
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Radiographic evaluation of conical tapered platform‐switched implants in the posterior mandible: 1‐year results of a two‐center prospective study

2015

Abstract Objective Long‐term success of dental implants depends on healthy peri‐implant soft tissues and adequate bone levels. This prospective study aims to assess bone level changes around implants with internal conical connection and platform‐switching abutments in the posterior mandible. Material and methods Adult patients missing at least two teeth in the posterior mandible and with a natural tooth mesial to the implant site received two or three adjacent internal conical connection implants. After a minimum transmucosal healing period of 8 weeks, single crown restorations were cemented over platform‐switching abutments. Changes in marginal bone levels were measured in standardized per…

0301 basic medicineMalemedicine.medical_treatmentRadiographyAlveolar Bone LossDentistryPilot ProjectsMandibleProsthesisOsseointegrationBone remodeling03 medical and health sciences0302 clinical medicineGermanySurveys and QuestionnairesmedicineHumansProspective StudiesDental implantbone remodelingplatform switchDental ImplantsBone preservationdental implantCrownsPortugalbusiness.industrySoft tissuebone levelDental Implant-Abutment Design030206 dentistryOriginal ArticlesMiddle Aged030104 developmental biologyconical connection implantsPatient SatisfactionoutcomeOriginal ArticleFemaleImplantDental Prosthesis Implant-SupportedOral SurgerybusinessClinical Oral Implants Research
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2018

Projections from the central nucleus of the amygdala (CEA) into the lateral hypothalamic area (LHA) show a very complex pattern. After injection of an anterograde tracer (Phaseolus vulgaris leucoagglutinin – PHAL) into several parts of the CEA, we observed that projections converged onto the caudal lateral LHA but provided distinct patterns in rostral tuberal regions. These projections were compared to that of neurons containing the peptides ‘melanin-concentrating hormone’ (MCH) or hypocretin (Hcrt). Because the distribution of these neurons is stereotyped, it was possible to characterize distinct divisions into the LHA. Some of them in the rostral tuberal LHA (the dorsal (LHAd) and suprafo…

0301 basic medicineMedial partDorsumLateral hypothalamusMelanin-concentrating hormoneCentral nucleus of the amygdalafood and beveragesPhaseolus vulgaris leucoagglutininAnatomyTract tracingBiologyAmygdala03 medical and health scienceschemistry.chemical_compound030104 developmental biology0302 clinical medicinemedicine.anatomical_structurenervous systemNeurologychemistrymedicineNeurology (clinical)030217 neurology & neurosurgeryFrontiers in Neurology
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Comparative Genomics of Thalassobius Including the Description of Thalassobius activus sp. nov., and Thalassobius autumnalis sp. nov.

2018

A taxogenomic study was conducted to describe two new Thalassobius species and to analyze the internal consistency of the genus Thalassobius along with Shimia and Thalassococcus. Strains CECT 5113T, CECT 5114, CECT 5118T, and CECT 5120 were isolated from coastal Mediterranean seawater, Spain. Cells were Gram-negative, non- motile coccobacilli, aerobic chemoorganotrophs, with an optimum temperature of 26°C and salinity of 3.5–5%. Major cellular fatty acids of strains CECT 5113T and CECT 5114 were C18 : 1 ω7c/ω6c and C10 : 0 3OH, G+C content was 54.4–54.5 mol% and were able to utilize propionate, L-threonine, L- arginine, and L-aspartate as carbon sources. They exhibited 98.3% 16S rRNA gene s…

0301 basic medicineMicrobiology (medical)Thalassobius030106 microbiologylcsh:QR1-502Microbiologylcsh:MicrobiologyMicrobiologyRoseobacter group03 medical and health sciencesGenusPrimary nutritional groupsRhodobacteraceaeRhodobacteraceaetaxogenomicsShimiaOriginal ResearchComparative genomicsStrain (chemistry)biologyThalassococcusThalassococcusphylogenomicsbiology.organism_classification16S ribosomal RNA030104 developmental biologyThalassobiusFrontiers in Microbiology
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Tricho-dento-osseous syndrome and precocious eruption

2017

Tricho-dento-osseous syndrome (TDO), an uncommon form of ectodermal dysplasia is an autosomal dominant genetic disorder which is characterized by inherited defects in tissues arising from epithelial-mesenchymal interaction. Genetic studies have revealed that it is caused by mutation in the DLX3 gene. TDO presents with a great phenotypic heterogeneity and studies have suggested that this heterogeneity is the result of environmental factors or other genetic modifiers. In this article, we report a case of TDO in which the child had typical clinical features of hair, teeth and bone defects, as seen in TDO. Parents of the child were unaffected. Genetic analysis of the child revealed mutation in …

0301 basic medicineMutationPathologymedicine.medical_specialtyEctodermal dysplasiaOral Medicine and PathologyGenetic heterogeneityDLX3Genetic disorderCase ReportBiology:CIENCIAS MÉDICAS [UNESCO]medicine.diseasemedicine.disease_causeGenetic analysisTricho-Dento-Osseous Syndrome03 medical and health sciencesstomatognathic diseases030104 developmental biologyUNESCO::CIENCIAS MÉDICASmedicineGeneral DentistryJournal of Clinical and Experimental Dentistry
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Microbial Colonization of the Peri-Implant Sulcus and Implant Connection of Implants Restored With Cemented Versus Screw-Retained Superstructures: A …

2016

The aim of this study is to investigate peri-implant and intraconnection microflora of healthy implants restored with cemented and screwed superstructures.Patients with two to three implants restored with cemented or screwed restorations and 5 years of follow-up were recruited. Samples were taken from peri-implant sulci, adjacent teeth, and the inner portion of connections. Prevalence of positive sites and bacterial loads for 10 microorganisms were obtained with quantitative real-time polymerase chain reaction. Implant connection permeability to the studied microorganisms was estimated using a standardized bacterial contamination index. Statistical analysis was performed using a generalized…

0301 basic medicinePeri-implantitisCross-sectional studyDental implantmedicine.medical_treatmentDentistryReal-Time Polymerase Chain ReactionProsthesisOsseointegration03 medical and health sciences0302 clinical medicinemedicineHumansDental implantDental Implantsimplant-supportedbusiness.industrymicrobiologydental implant abutment design030206 dentistrySulcusdental prosthesesBacterial Load030104 developmental biologymedicine.anatomical_structureDental Implant-Abutment DesignCross-Sectional StudiesPeriodonticsImplantDental implant; dental implant abutment design; dental prostheses implant-supported; microbiology; peri-implantitis; prosthesis.Dental Prosthesis Implant-Supportedprosthesisbusinessperi-implantitisJournal of periodontology
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Silica-gelatin hybrid sol-gel coatings: A proteomic study with biocompatibility implications.

2018

Osseointegration, including the foreign body reaction to biomaterials, is an immune‐modulated, multifactorial, and complex healing process in which various cells and mediators are involved. The buildup of the osseointegration process is immunological and inflammation‐driven, often triggered by the adsorption of proteins on the surfaces of the biomaterials and complement activation. New strategies for improving osseointegration use coatings as vehicles for osteogenic biomolecules delivery from implants. Natural polymers, such as gelatin, can mimic Collagen I and enhance the biocompatibility of a material. In this experimental study, two different base sol–gel formulations and their combinati…

0301 basic medicineProteomicsfood.ingredientBiocompatibilityBiomedical EngineeringMedicine (miscellaneous)02 engineering and technologyGelatinOsseointegrationCell LineimmunologyBiomaterials03 medical and health sciencesMicebiocompatibilityAdsorptionfoodbone regenerationCoated Materials BiocompatibleIn vivodental implantsMaterials TestingAnimalsBone regenerationCell Proliferationchemistry.chemical_classificationChemistryBiomoleculebiomaterialcomplement pathwayBiomaterial021001 nanoscience & nanotechnologySilicon Dioxide030104 developmental biologyChemical engineeringBone SubstitutesGelatinRabbits0210 nano-technologyJournal of tissue engineering and regenerative medicine
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Draft genomic sequence of Nereida ignava CECT 5292T, a marine bacterium of the family Rhodobacteraceae

2016

Nereida ignava strain 2SM4T (= CECT 5292T = DSM 16309T = CIP 108404T = CCUG 49433T) is a marine bacterium belonging to the Roseobacter group of the family Rhodobacteraceae within the class Alphaproteobacteria. The strain was isolated from sea water surrounding cultivated oysters 2–3 miles off the Mediterranean coast near Valencia (Spain) and was phylogenetically related to uncultured clones of gall symbiont bacteria of some species of Prionitis alga. Here we describe the genome sequence and annotation of this organism, the type strain of the single species of this genus. The genome comprised 2,888,349 bp, 2,872 protein-coding genes and 52 RNA genes. The annotation revealed the capacity to p…

0301 basic medicineWhole genome sequencingGeneticsbiologyNereida ignavaSlightly halophilicStrain (biology)Marine bacteria030106 microbiologyRoseobacterbiology.organism_classificationGenomeShort Genome ReportMicrobiology03 medical and health sciences030104 developmental biologyMarine bacteriophageBacteriocinStrictly aerobicMediterranean SeaGeneticsRhodobacteraceaeRhodobacteraceaeGeneStandards in Genomic Sciences
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Draft genome sequence of Thalassobius gelatinovorus CECT 4357 T , a roseobacter with the potential ability to degrade polycyclic aromatic hydrocarbons

2017

Abstract Thalassobius gelatinovorus is a member of the family Rhodobacteraceae previously classified in the genera Agrobacterium and Ruegeria . Strain Ahrens B6 T (= ATCC 25655 T , = B6 T , = CECT 4357 T , = CIP 105976 T , = DSM 5887 T , = IAM 12617 T , = JCM 20688 T , = KCTC 22092 T , = LMG 129 T , = NBRC 15761 T , = NCIMB 2206 T ) was isolated in 1967 from a sea water sampled in Kiel Fjord in Baltic Sea. Genomic DNA sequence of T. gelatinovorus CECT 4357 T was assembled into a draft genome and annotated. Here we report the main features of this draft genome composed by 3,902,797 bp arranged in 30 contigs with a G + C content of 58.4%, 3770 protein coding genes, 44 tRNA genes, 7 rRNA genes…

0301 basic medicineWhole genome sequencingbiologyRuegeria030106 microbiologyRibosomal RNARoseobacterbiology.organism_classificationGenome03 medical and health sciencesgenomic DNA030104 developmental biologyBiochemistryGeneticsRhodobacteraceaeGeneGene Reports
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Quercetin-Based Nanocomposites as a Tool to Improve Dental Disease Management

2020

The restoration and prosthetic rehabilitation of missing teeth are commonly performed using dental implants, which are extremely effective and long-lasting techniques due to their osteointegration ability with the preimplant tissues. Quercetin is a phytoestrogen-like flavonoid well known for its several positive effects on human health, mostly linked to the anti-inflammatory, antioxidant, and antibacterial activities against both Gram-positive and Gram-negative bacteria. Moreover, many studies in dentistry and the maxillofacial fields have highlighted the positive effects of quercetin on osteogenesis, acting on osteoblast activity and angiogenetic process, and promoting soft and hard tissue…

0301 basic medicinedental diseasemedicine.medical_treatmentMedicine (miscellaneous)DentistryReviewGeneral Biochemistry Genetics and Molecular BiologyOsseointegrationquercetin03 medical and health scienceschemistry.chemical_compoundHuman health0302 clinical medicineIn vivoantibacterial effectOral and maxillofacial pathologymedicineheterocyclic compoundsDental implantlcsh:QH301-705.5dental implantbusiness.industryRegeneration (biology)osteoinductive effectOsteoblast030206 dentistrymedicine.disease030104 developmental biologymedicine.anatomical_structurechemistrylcsh:Biology (General)businessQuercetinquercetin scaffoldBiomedicines
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