Search results for "SEX-DIFFERENCES"

showing 10 items of 17 documents

Gender medicine and oncology: report and consensus of an ESMO workshop.

2019

Background: The importance of sex and gender as modulators of disease biology and treatment outcomes is well known in other disciplines of medicine, such as cardiology, but remains an undervalued issue in oncology. Considering the increasing evidence for their relevance, European Society for Medical Oncology decided to address this topic and organized a multidisciplinary workshop in Lausanne, Switzerland, on 30 November and 1 December 2018.

0301 basic medicineOncologyMalemedicine.medical_specialtypopulation pharmacokinetic analysissuperior survivalDecision MakingMEDLINElymphomaDiseaseclearanceMedical Oncology03 medical and health sciences0302 clinical medicinerituximabInternal medicineNeoplasmsPhysiciansEpidemiologymedicinegendermelanomasexcancerHumansDosingfemale-patientsSex Characteristicsbusiness.industrygender medicineCancerHematologymedicine.diseaseChemotherapy regimenClinical trial030104 developmental biologyTreatment Outcome030220 oncology & carcinogenesisoncologyimpactBody CompositionFemalepharmacologybusinesssex-differencesSex characteristicsAnnals of oncology : official journal of the European Society for Medical Oncology
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Clinical Characteristics and Outcomes of Patients with COVID-19 Infection: The Results of the SARS-RAS Study of the Italian Society of Hypertension

2021

: The COVID-19 infection has rapidly spread around the world and a second wave is sweeping in many countries. Different clinical and epidemiological aspects characterize the disease and their understanding is necessary to better face the management of the pandemic in progress. The Italian society of arterial hypertension with the SARS-RAS study has contributed significantly to the knowledge of the interaction between inhibition of the renin-angiotensin system and COVID-19 infection. Furthermore, the study results help to understand some of the main aspects related to mortality and morbidity deriving from the infection through a multicentre analysis throughout the national territory.

0301 basic medicineSettore MED/09 - Medicina InternaCross-sectional studyDiseaseComorbiditySeverity of Illness IndexComorbiditiesRenin-Angiotensin System0302 clinical medicineRisk FactorsSex-differences.EpidemiologyPandemicFrailtySars-Cov2Treatment OutcomeItalyAnti-hypertensive therapy; comorbidities; frailty; Sars-Cov2; sex-differencesHypertensionComorbiditiePosition PaperRisk assessmentCardiology and Cardiovascular Medicinemedicine.medical_specialtySex-differenceRisk Assessment03 medical and health sciencesPharmacotherapySex FactorsSeverity of illnessmedicineAnti-hypertensive therapy Sars-Cov2 Frailty Comorbidities Sex-differencesInternal MedicineHumansArterial PressureAnti-hypertensive therapy Comorbidities Frailty Sars-Cov2 Sex-differencesIntensive care medicineAnti-hypertensive therapyAntihypertensive AgentsAnti-hypertensive therapy; Comorbidities; Frailty; Sars-Cov2; Sex-differences; Antihypertensive Agents; Arterial Pressure; COVID-19; Comorbidity; Cross-Sectional Studies; Frailty; Humans; Hypertension; Italy; Renin-Angiotensin System; Risk Assessment; Risk Factors; Severity of Illness Index; Sex Factors; Treatment OutcomeSettore MED/14 - Nefrologiabusiness.industryCOVID-19medicine.diseaseComorbiditySex-differences030104 developmental biologyCross-Sectional Studiesbusiness030217 neurology & neurosurgery
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Best performances by men and women open-water swimmers during the ‘English Channel Swim’ from 1900 to 2010

2012

Eichenberger, Evelyn | Knechtle, Beat | Knechtle, Patrizia | Ruest, Christoph Alexander | Rosemann, Thomas | Lepers, Romuald; International audience; ''Little research has examined ultra-endurance swimming performances. The 'English Channel Swim', where swimmers have to cover a distance of 32 km between England and France represents a unique long-distance, open-water, sea-swimming challenge, and each year swimmers from all over the world try to succeed in this challenge. The best times in minutes and the nationality of successful men and women swimmers were analysed from 1900 to 2010. A total of 1,533 swimmers (455 women and 1,078 men) from more than 40 countries have successfully completed…

11035 Institute of General PracticeMaleSEX-DIFFERENCESOceans and SeasPARTICIPATION610 Medicine & healthEXERCISEPhysical Therapy Sports Therapy and RehabilitationAthletic PerformanceULTRA-ENDURANCE SWIMMERSHistory 21st CenturyCAPACITY03 medical and health sciences2732 Orthopedics and Sports MedicineSex FactorsAGE0302 clinical medicineSex factorsHumansOrthopedics and Sports Medicine14. Life underwater030212 general & internal medicine3612 Physical Therapy Sports Therapy and RehabilitationPHYSIOLOGYSwimmingSimulation''ULTRA-ENDURANCE SWIMMERS[SCCO.NEUR]Cognitive science/NeuroscienceRACE PERFORMANCEHistory 19th Century030229 sport sciencesHistory 20th CenturyUnited KingdomUnited StatesOpen waterGeographyEnglandAGE''[ SCCO.NEUR ] Cognitive science/NeurosciencePhysical EnduranceNationalityFemaleFranceGENDERChannel (broadcasting)DemographyJournal of Sports Sciences
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Jealousy at work: The role of rivals’ characteristics

2018

The present study examined rival characteristics that may evoke jealousy in the workplace, differences between men and women in this regard, and the relationship between jealousy responses and intrasexual competitiveness and social comparison orientation. Participants were 426 male and female employees. By means of a questionnaire, participants were presented with a jealousy-evoking scenario after which jealousy responses to 24 rival characteristics were assessed. Findings showed that a rival's social communal attributes evoked highest levels of jealousy, and that, compared to men, women reported more jealousy in response to a rival's physical attractiveness. Overall, as individuals had hig…

AdultEmploymentMalesex differencesCompetitive BehaviorSEX-DIFFERENCESSocial comparison orientationmedia_common.quotation_subjectJealousy050109 social psychologyINDIVIDUAL-DIFFERENCES050105 experimental psychologyJealousyworkArts and Humanities (miscellaneous)social comparisonINTRASEXUAL COMPETITIONTESTOSTERONEDevelopmental and Educational PsychologymedicineHumansInterpersonal Relations0501 psychology and cognitive sciencesNEGATIVE EMOTIONSreproductive and urinary physiologyGeneral PsychologyCONFLICTmedia_commonSocial comparison theoryurogenital systemAggression05 social sciencesPhysical attractivenessGeneral MedicineMiddle AgedhumanitiesDominance (ethology)Social PerceptionDOMINANCESexual selectionFEMALE COMPETITIONAGGRESSIONFemaleWORKPLACEmedicine.symptomPsychologySocial psychologyScandinavian Journal of Psychology
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The relationship between cortisol and cognitive function in healthy older people: The moderating role of Apolipoprotein E polymorphism.

2018

The Apolipoprotein E4 (ApoE-epsilon 4) allele has been suggested as the main risk factor for late onset Alzheimer's disease (AD), whereas the ApoE-epsilon 2 allele has been proposed as a protective factor. These proposals have increased the interest in the effect of the ApoE genotype in healthy people. Additionally, high cortisol levels have been related to negative effects on cognition. However, few studies have investigated the relationship between cognitive performance and cortisol, taking into account the different ApoE alleles. For this reason, the aim of this study was to evaluate different cognitive domains (declarative and working memory, attention, and executive function) and their…

Apolipoprotein EMaleSALIVARY CORTISOLHydrocortisonePituitary-Adrenal SystemCortisolBehavioral NeuroscienceExecutive FunctionPOSTTRAUMATIC-STRESS-DISORDER0302 clinical medicineCognitionGenotypeSOCIOECONOMIC-STATUSAttentionPOPULATIONeducation.field_of_study05 social sciencesNeuropsychologyCognitionMiddle AgedALZHEIMERS-DISEASElipids (amino acids peptides and proteins)FemaleApolipoprotein Emedicine.medical_specialtyHypothalamo-Hypophyseal SystemSEX-DIFFERENCESCognitive NeurosciencePopulationExperimental and Cognitive PsychologyPolymorphism Single Nucleotide050105 experimental psychology03 medical and health sciencesApolipoproteins EMemoryAWAKENING RESPONSEInternal medicinemedicineHumans0501 psychology and cognitive sciencesEffects of sleep deprivation on cognitive performanceAlleleeducationAgedELDERLYWorking memorybusiness.industryMEMORY PERFORMANCEE GENOTYPEBODY-MASS INDEXEndocrinologyOlder peoplebusinessNeuroscience030217 neurology & neurosurgeryNeurobiology of learning and memory
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Gender differences in the jealousy-evoking effect of rival characteristics

2011

This study examines gender differences in the jealousy-evoking nature of rival characteristics in two Spanish-speaking countries (Argentina and Spain). A total of 388 Spanish students and 444 Argentinean students participated in the study. First, the cross-cultural validity of a Dutch scale containing 56 rival characteristics was examined. A factor analysis distinguished four dimensions (i.e., social power and dominance, physical attractiveness, physical dominance, and social-communal attributes). After the analysis, the final scale contained in total 24 items. Results showed that in Argentina and Spain combined, men experienced more jealousy than women when their rival was more physically …

Cultural StudiesSocial comparison orientationSEX-DIFFERENCESSocial Psychologymedia_common.quotation_subjectJealousyUNITED-STATEScultural differencesrival characteristicsINFIDELITYEVOLUTIONARY PERSPECTIVEDevelopmental psychologyJealousyCultural diversitysocial comparison orientationROMANTIC JEALOUSYmedia_commonPHYSICAL ATTRACTIVENESSPhysical attractivenessContrast (statistics)Social powerINDIVIDUALISM-COLLECTIVISMSELFDominance (ethology)EMOTIONSgender differencesAnthropologyScale (social sciences)PsychologySocial psychologyRESPONSESJournal of Cross-Cultural Psychology
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Major Congenital Anomalies in Babies Born With Down Syndrome

2014

Previous studies have shown that over 40% of babies with Down syndrome have a major cardiac anomaly and are more likely to have other major congenital anomalies. Since 2000, many countries in Europe have introduced national antenatal screening programs for Down syndrome. This study aimed to determine if the introduction of these screening programs and the subsequent termination of prenatally detected pregnancies were associated with any decline in the prevalence of additional anomalies in babies born with Down syndrome. The study sample consisted of 7,044 live births and fetal deaths with Down syndrome registered in 28 European population-based congenital anomaly registries covering seven m…

Heart Defects CongenitalMalemedicine.medical_specialtyDown syndromeSEX-DIFFERENCESEUROPEIMPACTDown syndromePrenatal diagnosisCardiac anomaliesPrenatal diagnosisHEART-DEFECTSDISEASECongenital AbnormalitiesSERUMSex FactorsAntenatal screeningGeneticsmedicineScreening programsHumansCARDIAC ANOMALYMALFORMATIONSRegistriesGenetics (clinical)prenatal diagnosisObstetricsbusiness.industrycardiac anomaliesInfant NewbornAbortion InducedEuropean populationmedicine.diseaseDown syndrome; cardiac anomalies; prenatal diagnosis3. Good healthPREVALENCELogistic ModelsFETAL NUCHAL TRANSLUCENCYFemalePopulation screeningbusinessPopulation-Based RegistryAmerican Journal of Medical Genetics. Part B: Neuropsychiatric Genetics
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The influence of personality on the effect of iTBS after being stressed on cortisol secretion

2019

Over the last years, individualization of repetitive Transcranial Magnetic Stimulation (rTMS) parameters has been a focus of attention in the field of non-invasive stimulation. It has been proposed that in stress-related disorders personality characteristics may influence the clinical outcome of rTMS. However, the underlying physiological mechanisms as to how personality may affect the rTMS response to stress remains to be clarified. In this sham-controlled crossover study, after being stressed by the Trier Social Stress Test, 38 healthy females received two sessions of intermittent theta burst stimulation (iTBS) applied to the left dorsolateral prefrontal cortex. To take possible personali…

MaleTRANSCRANIAL MAGNETIC STIMULATIONSALIVARY CORTISOLHydrocortisonePhysiologymedicine.medical_treatmentEmotionsIndividualitySocial SciencesHF-RTMS SESSIONPREFRONTAL CORTEXBiochemistryCortisol0302 clinical medicineMedicine and Health SciencesTrier social stress testPsychologyLipid Hormonesmedia_commonBrain MappingCross-Over StudiesMultidisciplinaryDepressionQRGeneral MedicineTranscranial Magnetic StimulationHealthy VolunteersElectrophysiologyBioassays and Physiological AnalysisBrain ElectrophysiologyMedicineFemaleGeneral Agricultural and Biological SciencesPsychologyResearch ArticlePersonalityClinical psychologyAdultCortisol secretionSEX-DIFFERENCESSciencePSYCHOSOCIAL STRESSmedia_common.quotation_subjectPsychological StressNeurophysiologyPrefrontal CortexGenetics and Molecular BiologyResearch and Analysis MethodsAffect (psychology)Young Adult03 medical and health sciencesMental Health and Psychiatry5-FACTOR MODELmedicineHumansPersonalityTranscranial StimulationSalivaSecretionPersonality TraitsSteroid HormonesMood DisordersUNDER-THE-CURVEElectrophysiological TechniquesCooperativenessBiology and Life SciencesMAJOR DEPRESSIONHormones030227 psychiatryTranscranial magnetic stimulationAffectMoodGeneral BiochemistryTemperament and Character InventoryPITUITARY-ADRENAL AXISPhysiological ProcessesStress Psychological030217 neurology & neurosurgeryNeuroscience
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Survival benefit from recent changes in management of men and women with ST-segment elevation myocardial infarction treated with percutaneous coronar…

2019

Background: Nowadays, the majority of patients with myocardial infarction with ST-segment elevation (STEMI) are treated with primary percutaneous coronary interventions (PCI). In recent years, there have been ongoing improvements in PCI techniques, devices and concomitant pharmacotherapy. However, reports on further mortality reduction among PCI-treated STEMI patients remain inconclusive. The aim of this study was to compare changes in management and mortality in PCI-treated STEMI patients between 2005 and 2011 in a real-life setting. Methods: Data on 79,522 PCI-treated patients with STEMI from Polish Registry of Acute Coronary Syndromes (PL-ACS) admitted to Polish hospitals between 2005 an…

MaleTime Factorsmedicine.medical_treatment030204 cardiovascular system & hematology0302 clinical medicinetemporal trendsRisk Factorstreatment strategyST segmentMyocardial infarctionHospital MortalityRegistriesPractice Patterns Physicians'Mortality rateGeneral MedicineMiddle AgedInterventional Cardiologysurgical procedures operativeTreatment OutcomePractice Guidelines as TopicCardiologyFemaleStentsGuideline AdherenceCardiology and Cardiovascular Medicinemedicine.medical_specialtyRisk Assessment03 medical and health sciencesPharmacotherapyPercutaneous Coronary InterventionSex FactorsInternal medicinemedicineHumanscardiovascular diseasesAcute Coronary SyndromeHealthcare DisparitiesAgedRetrospective Studiesbusiness.industryPercutaneous coronary interventionCardiovascular AgentsHealth Status Disparitiesmedicine.diseaseST-segment elevation myocardial infarctionConcomitantPropensity score matchingConventional PCI1-year mortalityST Elevation Myocardial InfarctionPolandbusinesssex-differencesin-hospital mortality
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Early life stress and frailty in old age: the Helsinki birth cohort study

2018

Background: Evidence suggests that early life stress (ELS) may extend its effect into adulthood and predispose an individual to adverse health outcomes. We investigated whether wartime parental separation, an indicator of severe ELS, would be associated with frailty in old age. Methods: Of the 972 participants belonging to the present sub-study of the Helsinki Birth Cohort Study, 117 (12. 0%) had been evacuated abroad unaccompanied by their parents in childhood during World War II. Frailty was assessed at a mean age of 71 years according to Fried's criteria. Results: Thirteen frail men (4 separated and 9 non-separated) and 20 frail women (2 separated and 18 non-separated) were identified. C…

MaleWorld War IImedicine.medical_treatmentEarly life stresslcsh:GeriatricsPHENOTYPE3124 Neurology and psychiatryCohort Studies0302 clinical medicineMALTREATMENT030212 general & internal medicineChildFinlandDepression (differential diagnoses)Aged 80 and overRehabilitationFrailtyConfoundingriskitekijätDEPRESSIONPREVALENCE5141 SociologyLife course approachFemaleHEALTHBirth cohortResearch ArticleSEX-DIFFERENCES515 Psychologylife-courseFrail Elderlyearly life stressfrailty03 medical and health sciencesINFLAMMATIONLife-courseterveysvaikutuksetmedicineHumansRisk factornatural experimentAgedADVERSE CHILDHOOD EXPERIENCESbusiness.industryDISABILITY3112 NeurosciencesADULTSstressiEarly life stresslapsuuslcsh:RC952-954.63121 General medicine internal medicine and other clinical medicineRelative risksotalapsetRisk factorGeriatrics and GerontologyNatural experimentbusinessStress Psychological030217 neurology & neurosurgeryFollow-Up StudiesDemographyBMC Geriatrics
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