Search results for "SHARP"
showing 10 items of 71 documents
Generalised stage-discharge relationship for rectangular weirs
2018
Rectangular weirs, which are very common hydraulic structures used in irrigation channels as water measuring devices, can be used for measuring very small discharges as well as high flow rates. From the practical point of view the availability of a unique stage-discharge formula that can be applied for the different types of the rectangular weirs would be of great practical importance. At first, in this paper the Buckingham’s Theorem of the dimensional analysis and the self-similarity theory are used to deduce the stage-discharge curve of different kinds of rectangular weirs such as slit and partially contracted ones. Then the proposed formula is calibrated using both the experimental data …
Meristic character analysis and skeletal anomalies during growth in reared sharpsnout seabream
2000
Sharpsnout seabream (Diplodus puntazzo) is a species currently reared in Mediterranean fish farms. In order to detect the main types of body deformation in sharpsnout seabream. 120 specimens (60 juveniles and 60 adults) taken from a Mediterranean hatchery were examined. In juveniles and adults non-significant differences were found in the number of vertebrae, dorsal spines and pectoral fin rays. Moreover, the number of anomalies varied with age. The juveniles presented 28 types of anomaly, the adults 25. The most important anomalies for juveniles (in terms of frequency of occurrence) were anomalous neural arch or spine (47%), anomalous hemal arch or spine (43%), fusion of hypurals (67%) and…
Pervasive access to MRI bias artifact suppression service on a grid.
2009
Bias artifact corrupts magnetic resonance images in such a way that the image is afflicted by illumination variations. Some of the authors proposed the Exponential Entropy Driven - Homomorphic Unsharp Masking (E2D-HUM) algorithm that corrects this artifact without any a priori hypothesis about the tissues or the Magnetic Resonance image modality. Moreover, E2D-HUM does not care about the body part under examination and does not require any particular training task. People who want to use this algorithm, which is Matlab-based, have to set their own computers in order to execute it. Furthermore, they have to be Matlab-skilled to exploit all the features of the algorithm. In our work we propos…
New theoretical solution of the outflow process with a weir with complex shape
2016
AbstractIn this paper, the outflow process of a weir with an irregular shape is studied using dimensional analysis and the incomplete self-similarity theory. The new unique stage–discharge relationship, which is deduced theoretically, represents a novel and comprehensive equation to describe the weir outflow process for a full range of flow and different geometric variables of weirs, including finite-crested weirs, broad-crested weirs with positive or negative crest slope, broad-crested weirs with an upstream, downstream, or both upstream and downstream crest ramps, and, triangular weirs with an upstream or downstream ramp. Finally the proposed stage–discharge relationship is calibrated usi…
Negative regulators of integrin activity
2012
Integrins are heterodimeric transmembrane adhesion receptors composed of α- and β-subunits. They are ubiquitously expressed and have key roles in a number of important biological processes, such as development, maintenance of tissue homeostasis and immunological responses. The activity of integrins, which indicates their affinity towards their ligands, is tightly regulated such that signals inside the cell cruicially regulate the switching between active and inactive states. An impaired ability to activate integrins is associated with many human diseases, including bleeding disorders and immune deficiencies, whereas inappropriate integrin activation has been linked to inflammatory disorders…
Pakottamalla vai käännyttämällä : Gene Sharpin ja Johan Galtungin väkivallattoman vallan vertailua
2016
Tämän tutkielman tehtävänä on selvittää miksi ja miten käsitys väkivallattomien toimijoiden vallasta Johan Galtungin Rauhanomaisen puolustuksen strategiassa poikkeaa siitä, miten Gene Sharpin The Politics of Nonviolent Action sen käsittää. Kirjat ovat samaan tutkijapolveen ja samoissa korkeakouluissakin opiskelleiden kirjoittajiensa pääasiallisia väkivallattoman kamppailun strategiaa käsitteleviä teoksia mutta Sharpin erikoistuminen nimenomaan väkivallattomuuden tutkimukseen ja Galtungin erikoistuminen rauhantutkimukseen antavat syyn olettaa niiden väliltä löytyvän myös kiinnostavia eroavaisuuksia. Tutkimuskysymykseen vastauksen löytämiseksi teosten esittämiä strategioita on vertailtu keske…
Sorafenib for Hepatocellular Carcinoma: From Randomized Controlled Trials to Clinical Practice.
2015
Hepatocellular carcinoma is a challenging malignancy of global importance. It is the sixth most common solid malignancy and the third leading cause of cancer-related death, worldwide. Curative treatments at early stages include liver transplantation, resection and percutaneous ablation, while transarterial chemoembolization can improve survival in patients with intermediate tumor stage. Patients with mild, related symptoms and/or macrovascular invasion or extrahepatic spread are classified under the advanced stage. The standard of care in this group is sorafenib, an inhibitor of Raf kinase and vascular endothelial growth factor receptor, whose effectiveness has been proven by 2 recent rando…
Symmetrization for singular semilinear elliptic equations
2012
In this paper, we prove some comparison results for the solution to a Dirichlet problem associated with a singular elliptic equation and we study how the summability of such a solution varies depending on the summability of the datum f. © 2012 Fondazione Annali di Matematica Pura ed Applicata and Springer-Verlag.
Optogenetically blocking sharp wave ripple events in sleep does not interfere with the formation of stable spatial representation in the CA1 area of …
2016
During hippocampal sharp wave/ripple (SWR) events, previously occurring, sensory inputdriven neuronal firing patterns are replayed. Such replay is thought to be important for plasticity-related processes and consolidation of memory traces. It has previously been shown that the electrical stimulation-induced disruption of SWR events interferes with learning in rodents in different experimental paradigms. On the other hand, the cognitive map theory posits that the plastic changes of the firing of hippocampal place cells constitute the electrophysiological counterpart of the spatial learning, observable at the behavioral level. Therefore, we tested whether intact SWR events occurring during th…
Characteristics and treatment regimens across ERS SHARP severe asthma registries
2020
Little is known about the characteristics and treatments of patients with severe asthma across Europe, but both are likely to vary. This is the first study in the European Respiratory Society Severe Heterogeneous Asthma Research collaboration, Patient-centred (SHARP) Clinical Research Collaboration and it is designed to explore these variations. Therefore, we aimed to compare characteristics of patients in European severe asthma registries and treatments before starting biologicals.This was a cross-sectional retrospective analysis of aggregated data from 11 national severe asthma registries that joined SHARP with established patient databases.Analysis of data from 3236 patients showed many …