Search results for "SHIFTS"
showing 10 items of 57 documents
Euclid Preparation. XIV. The Complete Calibration of the Color–Redshift Relation (C3R2) Survey: Data Release 3
2021
Stanford, S. A., et al.
Negotiating the Terminological Borders of ‘Language Mediation’ in English and Italian. A Discussion on the Repercussions of Terminology on the Practi…
2015
Linguistic and cultural mediation has been playing an increasingly important role in contemporary society as a result of the intensification of international exchanges and migration flows; however, the definitions that have been given of it are still rather vague and inconsistent. In some cases linguistic and cultural mediation is seen as a broad superordinate category, comprising a range of different interlinguistic and intercultural activities serving the purpose of facilitating communication across languages, cultures and societies in various areas of civil society: industry, business, trade, law, literature, academia, institutions, public services, etc. In other cases, instead, the defi…
Structure of SNX9 SH3 in complex with a viral ligand reveals the molecular basis of its unique specificity for alanine-containing class I SH3 motifs
2021
Class I SH3 domain-binding motifs generally comply with the consensus sequence [R/K]x0PxxP, the hydrophobic residue 0 being proline or leucine. We have studied the unusual 0 = Ala-specificity of SNX9 SH3 by determining its complex structure with a peptide present in eastern equine encephalitis virus (EEEV) nsP3. The structure revealed the length and composition of the n-Src loop as important factors determining specificity. We also compared the affinities of EEEV nsP3 peptide, its mutants, and cellular ligands to SNX9 SH3. These data suggest that nsP3 has evolved to minimize reduction of conformational entropy upon binding, hence acquiring stronger affinity, enabling takeover of SNX9. The R…
Language Mediation and Aspects of Accommodation in the Use of ELF
2014
There are numerous varieties of English spoken in Italy today, each repre-sented by one or more of the various migrant communities living in the country. These manifestations of World englishes reflect a wide range of lexical, syntactical, phonetic, pragmatic, interpersonal and cultural features. This paper argues that an interpreter or language mediator trained in standard English may not necessarily be able to comprehend or make him/herself understood adequately in other varieties of English. Thus, the recruitment of mediators/interpreters requires a certain amount of caution in terms of language choice. In order to investigate intelligibility, comprehensibility and accommodation in the c…
Energy level shifts of a uniformly accelerated atom in the presence of boundary conditions
2009
We discuss the radiative level shifts of an atom moving with uniform acceleration near an infinite reflecting plate. We first consider the case of a two-level system interacting with a massless scalar field in the vacuum state. The acceleration of the two-level atom is supposed in a direction parallel to the conducting plate. We evaluate the contribution of vacuum fluctuations and of the radiation reaction field to the energy shift of the atomic levels, and discuss their behaviour as a function of the atomic acceleration and of the atom-plate distance. Then, we investigate the more general case of an hydrogen atom accelerating near a perfectly reflecting plate and interacting with the elect…
A GRASP algorithm for the container stowage slot planning problem
2016
This work presents a generalization of the Slot Planning Problem which raises when the liner shipping industry needs to plan the placement of containers within a vessel (stowage planning). State-of-the-art stowage planning relies on a heuristic decomposition where containers are first distributed in clusters along the vessel. For each of those clusters a specific position for each container must be found. Compared to previous studies, we have introduced two new features: the explicit handling of rolled out containers and the inclusion of separations rules for dangerous cargo. We present a novel integer programming formulation and a Greedy Randomized Adaptive Search Procedure (GRASP) to solv…
The evolution of transmission mode
2017
This article reviews research on the evolutionary mechanisms leading to different transmission modes. Such modes are often under genetic control of the host or the pathogen, and often in conflict with each other via trade-offs. Transmission modes may vary among pathogen strains and among host populations. Evolutionary changes in transmission mode have been inferred through experimental and phylogenetic studies, including changes in transmission associated with host shifts and with evolution of the unusually complex life cycles of many parasites. Understanding the forces that determine the evolution of particular transmission modes presents a fascinating medley of problems for which there is…
A New Entry to the Substituted Pyrrolo[3,2-c]quinoline Derivatives of Biological Interest by Intramolecular Heteroannulation of Internal Imines.
2004
New 1,3,4-substituted pyrrolo[3,2-c]quinoline derivatives were synthesised in good yields by oxidative heteroannulation of internal imines starting from easily prepared substituted 5-(2-aminophenyl)pyrroles and commercially available aryl and heteroaryl aldehydes. The reaction occurs as a one-pot process involving an intramolecular acid catalysed reaction.
Changes in nuclear structure along the Mn isotopic chain studied via charge radii
2016
The hyperfine spectra of $^{51,53-64}$Mn were measured in two experimental runs using collinear laser spectroscopy at ISOLDE, CERN. Laser spectroscopy was performed on the atomic $3d^5\ 4s^2\ ^{6}\text{S}_{5/2}\rightarrow 3d^5\ 4s4p\ ^{6}\text{P}_{3/2}$ and ionic $3d^5\ 4s\ ^{5}\text{S}_2 \rightarrow 3d^5\ 4p\ ^{5}\text{P}_3$ transitions, yielding two sets of isotope shifts. The mass and field shift factors for both transitions have been calculated in the multiconfiguration Dirac-Fock framework and were combined with a King plot analysis in order to obtain a consistent set of mean-square charge radii which, together with earlier work on neutron-deficient Mn, allow the study of nuclear struc…
Nuclear charge radii of 62−80Zn and their dependence on cross-shell proton excitations
2019
Nuclear charge radii of 62−80Zn have been determined using collinear laser spectroscopy of bunched ion beams at CERN-ISOLDE. The subtle variations of observed charge radii, both within one isotope and along the full range of neutron numbers, are found to be well described in terms of the proton excitations across the Z=28 shell gap, as predicted by large-scale shell model calculations. It comprehensively explains the changes in isomer-to-ground state mean square charge radii of 69−79Zn, the inversion of the odd-even staggering around N=40 and the odd-even staggering systematics of the Zn charge radii. With two protons above Z=28, the observed charge radii of the Zn isotopic chain show a cum…