Search results for "SHM"
showing 10 items of 400 documents
Leishmania tarentolae and Leishmania infantum in humans, dogs and cats in the Pelagie archipelago, southern Italy.
2021
Visceral leishmaniasis (VL) caused by Leishmania infantum is endemic in the Mediterranean basin with most of the infected human patients remaining asymptomatic. Recently, the saurian-associated Leishmania tarentolae was detected in human blood donors and in sheltered dogs. The circulation of L. infantum and L. tarentolae was investigated in humans, dogs and cats living in the Pelagie islands (Sicily, Italy) by multiple serological and molecular testing. Human serum samples (n = 346) were tested to assess the exposure to L. infantum by immunofluorescence antibody test (IFAT), enzyme-linked immunosorbent assay (ELISA) and Western blot (WB) and to L. tarentolae by IFAT. Meanwhile, sera from do…
"Click" on PLGA-PEG and hyaluronic acid: gaining access to anti-leishmanial pentamidine bioconjugates
2018
Pentamidine (Pent), an antiparasitic drug used for the treatment of visceral leishmaniasis, has been modified with terminal azide groups and conjugated to two different polymer backbones (PLGA-PEG [PP] copolymer and hyaluronic acid [HA]) armed with alkyne end-groups. The conjugation has been performed by Copper Catalyzed Azido Alkyne Cycloaddition (CuAAC) using CuSO4/sodium ascorbate as metal source. The novel PP-Pent and HA-Pent bioconjugates are proposed, respectively, as non-targeted and targeted drug delivery systems against Leishmania infections. Moreover, Pent has been encapsulated into PP nanoparticles by the oil-in-water emulsion method, with the aim to compare the biological activi…
Evolution of impatience: The example of the Farmer-Sheriff game
2015
The literature on the evolution of impatience, focusing on one-person decision problems, often finds that evolutionary forces favor the more patient individuals. This paper shows that in games where equilibrium involves threat of punishment there are forces generating an evolutionary advantage to the impatient. In particular, it offers a two-population example where evolutionary forces favor impatience in one group while favoring patience in the other. Moreover, efficiency may also favor impatient individuals. In our example, it is efficient for one population to evolve impatience and for the other to develop patience. Yet, evolutionary forces move the opposite direction. Fil: Levine, David…
Sytuacja uwięzionych kobiet w dwudziestoleciu międzywojennym
2015
The first legal document that introduced a distinction of treatment between imprisoned men and women was created during the interwar period. At that time, the need to differentiate the execution of the penalty methods between men and women was emphasized. This particular period initiated the beginning of formulating separate regulations related to the issue of imprisoned women. At first, they were treated as a homogeneous population. However, after some time, the need for alternative treatment of female prisoners, especially pregnant and breastfeeding, was noticed. Gradually, taking into account gender differences in the penitentiary interactions, slow evolution was taking place, especially…
Seroprevalence of and risk factors for Leishmania seropositivity in a sample population of Western Sicily (Italy)
2013
Background: Leishmania is a vector-borne parasite responsible for significant morbidity and mortality worldwide. The aim of this study was to assess the prevalence of and risk factors for Leishmania infantum seropositivity in a sample of Sicilian population.Methods: A total of 260 subjects were interviewed using a standardized questionnaire and requested for an venous blood sample.Results: Overall, 36 subjects (13.8%) were seropositive against L. infantum with a statistically significant higher prevalence of positivity in older subjects (p=0.04). After adjustment for age, a higher risk for Leishmania seropositivity was found in subjects who had pets living outdoors and untreated with anti-p…
Long-Term Field Evaluation of Conventional vs. Micropropagated Plants of Chrysanthemum cinerariifolium
2022
Pyrethrum is a perennial herbaceous plant endemic to the eastern coast of the Adriatic Sea, and introduced in large areas of nearly all continents, where it is cultivated for the industrial extraction of pyrethrins. Pyrethrins are a group of six closely related monoterpene esters, widely used as natural insecticides. The world production of natural pyrethrins is lower than the market demand, and a wider introduction of this crop within the Mediterranean agrosystems could be an appealing opportunity for farmers and manufacturers. The availability of adequate amounts of selected plant material to bring into cultivation is, however, one of the major issues. Therefore, the in vitro propagation …
IT-Supported International Subsidiary Establishment Process for the Japanese Market: A Case Study on Finnish High Technology SMEs
2005
The large size of the Japanese IT market makes it attractive to and important for foreign high technology companies. However, the Japanese market is very challenging, highly competitive, and difficult to penetrate for foreign small and medium-sized enterprises (SMEs). Most SMEs fail to penetrate into the Japanese market effectively by using modern IT-tools in the international subsidiary establishment process. No earlier in-depth empirical research exists on the IT-supported international subsidiary establishment process for this market. This study investigated and analyzed how a Finnish high technology SME implemented the ITsupported international subsidiary establishment process for the J…
A Conceptual Model for the IT-supported International Subsidiary Establishment Process
2004
This study examines how the IT-supported international subsidiary establishment process can be implemented. An in-depth literature review uncovered that there is a significant lack of literature to guide managers about how to execute the establishment process of a subsidiary through the support of various IT-tools. This study, by answering the research question “What are the phases in the establishment of a subsidiary through IT-support and how have the phases been executed?” introduces a conceptual model for the IT-supported international subsidiary establishment process. The research findings are useful for both practice and further research. peerReviewed
Metodología innovadora en la universidad: sus efectos sobre los procesos de aprendizaje de los estudiantes universitarios
2015
Se pretendía evaluar el impacto de metodología centrada en el aprendizaje sobre las estrategias de aprendizaje y los enfoques de aprendizaje de un grupo de alumnos de Química, de 1º curso de Ingeniería, de la Universitat Politécnica de Valencia. Se utilizó un diseño preexperimental, con medidas de pretest y postest, tomadas mediante el cuestionario CEVEAPEU y el CPE. La muestra estaba constituida por 20 alumnos. Los métodos docentes utilizados integraban metodología expositiva, preguntas, resolución de problemas, elaboración de una monografía, exposiciones orales, prácticas de laboratorio, trabajo en grupo, tutorías en el aula y un sistema de evaluación que hacía uso de procedimientos forma…
Effect of Feed Protein : Lipid Ratio on Growth Parameters of African Catfish Clarias gariepinus after Fish Meal Substitution in the Diet with Bambara…
2017
Fishmeal (FM) was substituted with soybean meal (Glycine max) (SBM) and bambaranut meal (Voandzeia subterranea) (BNM) in 10 experimental African catfish, Clarias gariepinus, diets. Feed formulation was designed using mixture model. The inclusion level of the three protein ingredients varied between 0% and 60%. Remaining 40% comprised of basal ingredients kept constant for all 10 feeds. African catfish of average initial weight 35.2 ± 0.9 g were fed with one of the treatment diets for 28 days. The protein:lipid ratios of the diets (range 1.5–3.4:1) were used in evaluating the feed utilization and growth of the fish. We found that catfish performances were mainly depending on ingredients and …