Search results for "SHM"
showing 10 items of 400 documents
Leishmaniasis in travelers: A literature review.
2014
Leishmaniasis is a vector-borne protozoan infection whose clinical spectrum ranges from asymptomatic infection to fatal visceral leishmaniasis. Over the last decades, an increase in imported leishmaniasis cases in developed, non-endemic countries, have been pointed-out from a review of the international literature. Among the possible causes are increasing international tourism, influx of immigrants from endemic regions and military operations. The main area for the acquisition of cutaneous leishmaniasis, especially for adventure travelers on long-term trips in highly-endemic forested areas, is represented from South America, whereas popular Mediterranean destinations are emerging as the mai…
Mathematical formulation of pulse amplitude modulation selective harmonic elimination in multilevel three phase inverters
2022
In this paper multilevel cascaded H-bridges (CHB) three phase inverters with 2n dc sources, n=1,2,3,... are considered and a mathematical formulation providing both 2n switching angles and dc voltage source to eliminate n+1 harmonics and their respective multiple from their output voltage waveform, is proposed. The computed angles don't depend on modulation index and the source voltages linearly vary with it. The proposed procedure finds the solution through an analytical formula that avoids to solve transcendental systems and presents very low computational cost. A lot of low order harmonics are eliminated, returning a very low total harmonic distortion (THD). Particularly for 9-level conf…
Skin-derived macrophages from Leishmania major-susceptible mice exhibit interleukin-12- and interferon-gamma-independent nitric oxide production and …
2002
Co-administration of CpG-containing immunostimulatory oligodeoxynucleotides and parasite antigen protects susceptible BALB/c mice from otherwise progressive infection with Leishmania major. Although the protective effect of CpG-containing immunostimulatory oligodeoxynucleotides is clearly dependent on endogenous interleukin-12 and interferon-gamma production, the source of these Th1-promoting cytokines in infected mice is unknown. In contrast to macrophages from Leishmania-resistant C57BL/6 mice, macrophages from susceptible BALB/c mice are hyporesponsive to stimulation with lipopolysaccharide and interferon-gamma. While studying interactions of various antigen-presenting cells with Leishma…
Leishmaniasis among organ transplant recipients.
2008
Leishmaniasis is a rarely reported disease among transplant recipients; however, the number of published cases has quadrupled since the beginning of the 1990s. Most cases have been observed in patients living in countries of the Mediterranean basin. Leishmaniasis is most commonly associated with kidney transplantation (77%), and cases are also recorded among patients undergoing liver, heart, lung, pancreas, and bone marrow transplantation. Visceral leishmaniasis (VL) is the most frequently observed clinical presentation, followed by mucosal leishmaniasis and more rarely cutaneous leishmaniasis. Transplant recipients with VL develop the classic clinical form of the disease, which is a febril…
Are the Best Available Technologies the only viable for energy interventions in historical buildings?
2014
Worth aged buildings represent among the existing buildings a special case when it comes to their energy refurbishment. Current available technologies for building components, characterized by high level of thermal performances, unfortunately, are also characterized, not rarely, by limited compatibility with the architectural integrity of the building. In other words, the so-called Best Available Technologies that are effectively adopted to optimize the energy performances of buildings, in the case of aged buildings to which a certain artistic, historic and/or architectural merit is recognized (heritage houses) could, actually, determine such kind of conflicts and therefore leading to the s…
Coordinated Punishment and the Evolution of Cooperation
2015
In this paper, we analyze a team trust game with coordinated Q1 punishment of the allocator by investors and where there is also a final stage of peer punishment. We study the effect of punishment on the reward and the investment decisions, when the effectiveness and cost of coordinated punishment depend on the number of investors adhering to this activity. The interaction takes place in an overlapping-generations model with heterogeneous preferences and incomplete information. The only long-run outcomes of the dynamics are either a fully cooperative culture (FCC) with high levels of trust and cooperation and fair returns or a non-cooperative culture with no cooperation at all. The basin of…
Estonian e-Residency: a model for Europe
2020
This paper aims to examine one of the main implications of freedom of establishment: since it is possible to transfer a company abroad effortlessly, in fact, governments are adopting various strategies to make themselves more attractive. These are based on two main directives: first, a convenient tax system, as in Malta, on the other side technology, as proposed in Estonia. These countries’ strategy is radically different: Malta offers an extremely profitable tax system, while Estonia, on the other side, is the only nation in Europe where the optimal use of technology and its potential allows the consolidation and implementation of a totally digital system, whose advantages outweigh those o…
La gestión de expedientes juveniles de reforma (I): un análisis de su tramitación en la fiscalía provincial de valencia (2011)
2023
Se analizan la tramitación procesal de los expedientes penales incoados a menores de edad en la provincia de Valencia durante el año 2011, estudiando la exploración del menor y la derivación –o no– a mediación. Se deja para una segunda parte el análisis de los supuestos en que se realiza escrito de alegaciones, se sustancia vista y en su caso se impone medida. The procedural processing of criminal files initiated against minors in the province of Valencia during the year 2011 is analyzed, studying the exploration of the minor and the referral –or not– to mediation. The analysis of the cases in which a statement of allegations is made, the hearing is substantiated and, where appropriate, a m…
Diagnosis and therapy of cutaneous and mucocutaneous Leishmaniasis in Germany
2011
The incidence of cutaneous and mucocutaneous Leishmaniasis (CL/MCL) is increasing globally, also in Germany, although the cases are imported and still low in number. The current evidence for the different therapies has many limitations due to lack of sufficient studies on the different Leishmania species with differing virulence. So far there is no international gold standard for the optimal management. The aim of the German joint working group on Leishmaniasis, formed by the societies of Tropical Medicine (DTG), Chemotherapy (PEG) and Dermatology (DDG), was to establish a guideline for the diagnosis and treatment of CL and MCL in Germany, based on evidence (Medline search yielded 400 artic…
Cytotoxicity and antileishmanial activity of Annona muricata pericarp
2000
Abstract Hexane, ethyl acetate and methanol extracts of Annona muricata pericarp were tested in vitro against Leishmania braziliensis and L. panamensis promastigotes, and against cell line U-937. The ethyl acetate extract was more active than the other extracts and even of Glucantime® used as reference substance. Its fractionation led to the isolation of three acetogenins — annonacin, annonacin A and annomuricin A.