Search results for "SHO"
showing 10 items of 5071 documents
The hippocampus is required for short-term topographical memory in humans.
2007
The hippocampus plays a crucial role within the neural systems for long-term memory, but little if any role in the short-term retention of some types of stimuli. Nonetheless, the hippocampus may be specialized for allocentric topographical processing, which impacts on short-term memory or even perception. To investigate this we developed performance-matched tests of perception (match-to-sample) and short-term memory (2 s delayed-match-to-sample) for the topography and for the nonspatial aspects of visual scenes. Four patients with focal hippocampal damage and one with more extensive damage, including right parahippocampal gyrus, were tested. All five patients showed impaired topographical m…
Primary motor area contribution to attentional reorienting after distraction
2008
The anatomical structures involved in distraction-related processing in the auditory domain were investigated using magnetoencephalography. Participants performed a duration-discrimination task on a sequence of 200 and 400 ms long tones. Infrequent (12%) task-irrelevant pitch changes resulted in slower discriminative responses and more errors. Event-related potentials to these changes show an increased N1, a mismatch negativity, a P3a, and a reorienting negativity. The event-related magnetic fields revealed focal activities in superior and medial temporal areas in the N1/mismatch negativity time range. No significant activity was found in the P3a interval. In the reorienting negativity inte…
Contralateral hand anesthesia transiently improves poststroke sensory deficits.
2005
Objective To test a possible strategy to alleviate somatosensory deficits after stroke. Methods Here, we applied ischemic nerve block to the intact hand of patients with chronic stroke, which in healthy subjects elicits improvements in sensibility of the other hand. Results We found that sensibility in the affected hand improved with intact hand anesthesia, but not with intact foot anesthesia or no anesthesia. Interpretation We conclude that reduction of sensory input from the intact hand leads to site-specific improvements in tactile discriminative skills in the affected hand after the period of anesthesia, a potentially relevant finding in designing neurorehabilitative interventions. Ann …
Working Memory in Children: A Time-Constrained Functioning Similar to Adults
2009
International audience; Within the Time-Based Resource-Sharing (TBRS) model, we tested a new conception of the relationships between processing and storage in which the core mechanisms of WM are time constrained. However, our previous studies were restricted to adults. The present study aimed at demonstrating that these mechanisms are present and functional before adulthood. For this purpose, we investigated the effect on maintenance of the duration of the attentional capture induced by processing. In two experiments using computer-paced WM span tasks, 10- year-old children were asked to maintain letters while performing spatial location judgments. The duration of this processing was manipu…
Characteristics of tinnitus with or without hearing loss: Clinical observations in Sicilian tinnitus patients
2010
Objective: To analyze the clinical characteristics of tinnitus both in normal hearing subjects and in patients with hearing loss. Methods: The study considered 312 tinnitus sufferers, 176 males and 136 females, ranging from 21 to 83 years of age, who were referred to the Audiology Section of the Department of Bio-technology of Palermo University. The following parameters were considered: age, sex, hearing threshold, tinnitus laterality, tinnitus duration, tinnitus measurements and subjective disturbance caused by tinnitus. The sample was divided into two groups: Group 1 (G1) subjects with normal hearing; Group 2 (G2) subjects with hearing loss. Results: Among the patients considered, 115 ha…
The effect of vibration therapy on neck myofascial trigger points: A randomized controlled pilot study
2020
[EN] Background: The purpose of this study was to evaluate the effect of low-frequency self-administered vibration therapy into myofascial trigger points in the upper trapezius and levator scapulae on patients with chronic non-specific neck pain. Methods: Twenty-eight patients with chronic non-specific neck pain were randomly assigned into a vibration group, receiving 10 self-applied sessions of vibration therapy in the upper trapezius and levator scapulae trigger points; or a control group, receiving no intervention. Self-reported neck pain and disability (Neck Disability Index) and pressure pain threshold were assessed at baseline and after the first, fifth and 10th treatment sessions. Fi…
Tumor in the Horseshoe Kidney: Clinical Implications and Review of Embryogenesis
1992
We report on 3 patients with tumor in a horseshoe kidney, 1 of whom had bilateral tumor (renal cell cancer on the right side and urothelial cancer on the left side). Tumors that arise predominantly in the bridge of a horseshoe kidney can mimic the symptoms of an intra-abdominal disease process. Besides routine diagnostic procedures, angiography is essential to plan the surgical approach, which in principle should be organ-sparing. The literature of the embryology of the horseshoe kidney was reviewed for a relationship between the abnormal renal development and the site of tumorigenesis, and for development of a key for the wide variation of blood supply. Recently reported data suggest that …
Neural correlates of working memory dysfunction in first-episode schizophrenia patients: an fMRI multi-center study.
2005
Working memory dysfunction is a prominent impairment in patients with schizophrenia. Our aim was to determine cerebral dysfunctions by means of functional magnetic resonance imaging (fMRI) in a large sample of first-episode schizophrenia patients during a working memory task. 75 first-episode schizophrenia patients and 81 control subjects, recruited within a multi-center study, performed 2- and 0-back tasks while brain activation was measured with fMRI. In order to guarantee comparability between data quality from different scanners, we developed and adopted a standardized, fully automated quality assurance of scanner hard- and software as well as a measure for in vivo data quality. After t…
Altered effective connectivity during working memory performance in schizophrenia: a study with fMRI and structural equation modeling
2003
The present study aimed to explore altered effective connectivity in schizophrenic patients while performing a 2-back working memory task. Twelve right-handed, schizophrenic patients treated with typical or atypical antipsychotics and 6 healthy control subjects were studied with fMRI while performing a "2-back" working memory task. Effective connectivity within a cortical-subcortical-cerebellar network for mnemonic information processing was assessed and compared between both groups. The path model included cortico-cortical connections comprising the parietal association cortex, ventrolateral prefrontal cortex (VLPFC), and the dorsolateral prefrontal cortex (DLPFC) as well as a cortico-cere…
Limitations of concurrently representing objects within view and in visual working memory
2020
AbstractRepresenting visibly present stimuli is as limited in capacity as representing invisible stimuli in visual working memory (WM). In this study, we explored whether concurrently representing stimuli within view affects representing objects in visual WM, and if so, whether this effect is modulated by the storage states (active and silent state) of memory contents? In experiment 1, participants were asked to perform the change-detect task in a simultaneous-representing condition in which WM content and the continuously-visible stimuli in view were simultaneously represented, as well as a baseline condition in which only the representations of visual WM content were maintained. The resul…