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RESEARCH PRODUCT
Contralateral hand anesthesia transiently improves poststroke sensory deficits.
Carolyn W.-h. WuBernhard VollerBernhard VollerShashi RavindranAgnes FlöelAgnes FlöelKonrad J. WerhahnKonrad J. WerhahnLeonardo G. Cohensubject
AdultMaleTime Factorsmedicine.medical_treatmentSensory systemSomatosensory systemFunctional LateralityDouble-Blind MethodReaction TimeMedicineHumansAnesthesiaChronic strokeStrokeAgedAnalysis of VarianceHand Strengthbusiness.industryHealthy subjectsMiddle Agedmedicine.diseaseHandStrokeSensory inputNeurologyAnesthesiaSensory ThresholdsSensation DisordersNerve blockFemaleNeurology (clinical)businessPsychomotor Performancedescription
Objective To test a possible strategy to alleviate somatosensory deficits after stroke. Methods Here, we applied ischemic nerve block to the intact hand of patients with chronic stroke, which in healthy subjects elicits improvements in sensibility of the other hand. Results We found that sensibility in the affected hand improved with intact hand anesthesia, but not with intact foot anesthesia or no anesthesia. Interpretation We conclude that reduction of sensory input from the intact hand leads to site-specific improvements in tactile discriminative skills in the affected hand after the period of anesthesia, a potentially relevant finding in designing neurorehabilitative interventions. Ann Neurol 2006
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2005-12-15 | Annals of neurology |