Search results for "SIGNATURE"
showing 10 items of 218 documents
Hydro-Acoustic Target Detection
2014
This chapter presents an example of utilization of the discrete–time wavelet packets, which are described in Sect. 9.1, to classification of acoustic signals and detection of a target. The methodology based on wavelet packets is applied to a problem of detection of a boat of a certain type when other background noises are present. The solution is obtained via analysis of boat’s hydro-acoustic signature against an existing database of recorded and processed hydro-acoustic signals. The signals are characterized by the distribution of their energies among blocks of wavelet packet coefficients.
Clinical Utility of a Unique Genome-Wide DNA Methylation Signature for KMT2A-Related Syndrome
2022
Wiedemann–Steiner syndrome (WDSTS) is a Mendelian syndromic intellectual disability (ID) condition associated with hypertrichosis cubiti, short stature, and characteristic facies caused by pathogenic variants in the KMT2A gene. Clinical features can be inconclusive in mild and unusual WDSTS presentations with variable ID (mild to severe), facies (typical or not) and other associated malformations (bone, cerebral, renal, cardiac and ophthalmological anomalies). Interpretation and classification of rare KMT2A variants can be challenging. A genome-wide DNA methylation episignature for KMT2A-related syndrome could allow functional classification of variants and provide insights into the pathoph…
Adopting XML for Large-Scale Information
2011
This book has presented many different ways to encode information in XML format and the purposes for doing so. In this concluding chapter we consider problems related to managing XML information assets and the methods available to address those problems. Approaches for persistently storing XML data can be divided into file storage and database storage, and the research community has been especially active in designing new solutions for XML databases. However, adoption of XML often means massive migration procedures from some legacy data into the XML format; examples of migration cases are given. While describing the problems related to adopting XML, we give examples of the kinds of data fo…
Why Use XML?
2011
Since its inception a decade ago, XML has become a standard technology for software engineers, all Web browsers are able to parse and show XML documents, and huge XML data resources are available from the Internet. Many of the documents are in XHTML, but other XML applications are quite common as well. XML has also become a format that is increasingly common in the files of local disks. This success would not have been possible without collaborative efforts throughout the Web community. Such world-wide collaborative development has included standards, software applications, and case implementations that can serve as models when developing new solutions. In this chapter we consider what ki…
H-2 vibrational spectral signatures in binary and ternary mixtures: theoretical model, simulation and application to CARS thermometry in high pressur…
2001
International audience; A summary of the main results obtained by the two groups in the field of H-2 vibrational spectral line signatures for various mixtures. in connection with CARS diagnostics of H-2-O-2 combustion systems, is presented. H-2-X Systems may have specific large inhomogeneous spectral features, due to the dependence of the line broadening and line shifting on the (H-2) radiator speed, particularly at high temperature. Thus, careful attention has to be paid to rigorously analyze such features, both from the experimental point of view (Dijon) and from the theoretical one (Besancon). Applications of the present results to high-pressure H-2/air flame thermometry are also briefly…
Disentangling the complexity and diversity of crosstalks between S and other mineral nutrients in cultivated plants
2018
International audience
La combinaison de cartographie de signatures de sélection, de re-séquençage de génomes et d'analyses d'expression révèle PARK2 et JAG2 comme nouveaux…
2015
Very few causal genes have been identified by quantitative trait loci (QTLs) mapping because of the large size ofQTLs, and most of them were identified thanks to functional links already known with the targeted phenotype.Here we propose to combine selection signature detection, SNP annotation, and expression analyses to identifycausal genes underlying QTLs. As a model, we chose experimental chicken lines divergently selected for onlyone trait, the abdominal fat weight, in which several QTLs were previously mapped. Using a new haplotypebasedstatistics exploiting the very high SNP density generated through whole genome re-sequencing, we found129 significant selective sweeps. Most of the QTLs …
Runs of homozygosity in the Italian goat breeds: impact of management practices in low-input systems
2021
Abstract Background Climate and farming systems, several of which are considered as low-input agricultural systems, vary between goat populations from Northern and Southern Italy and have led to different management practices. These processes have impacted genome shaping in terms of inbreeding and regions under selection and resulted in differences between the northern and southern populations. Both inbreeding and signatures of selection can be pinpointed by the analysis of runs of homozygosity (ROH), which provides useful information to assist the management of this species in different rural areas. Results We analyzed the ROH distribution and inbreeding (FROH) in 902 goats from the Italia…
Mycorrhizal symbiosis changes host nitrogen source use
2021
Abstract Purpose The ecological importance of arbuscular mycorrhizal fungi (AMF) in plant acquisition of inorganic and organic sources of nitrogen (N) is not clear. To improve understanding of the plant N nutrition ecology, we tested the effect of intraspecific competition and AMF in plant N source use in growth and N acquisition. Methods Solidago virgaurea was grown in microcosms in a fully factorial experiment under greenhouse conditions. The factors tested were intraspecific competition between seedlings and adult plants (yes, no), N source (NH4, glycine) and AMF (inoculated with Glomus hoi, not inoculated). Results When grown separately, non-mycorrhizal seedling growth was highest when …
Proton-irradiated breast cells: molecular points of view
2019
Abstract Breast cancer (BC) is the most common cancer in women, highly heterogeneous at both the clinical and molecular level. Radiation therapy (RT) represents an efficient modality to treat localized tumor in BC care, although the choice of a unique treatment plan for all BC patients, including RT, may not be the best option. Technological advances in RT are evolving with the use of charged particle beams (i.e. protons) which, due to a more localized delivery of the radiation dose, reduce the dose administered to the heart compared with conventional RT. However, few data regarding proton-induced molecular changes are currently available. The aim of this study was to investigate and descri…