Search results for "SIM"
showing 10 items of 10139 documents
Ansaittu todellisuus : kvasi-realistisen position luonteesta, perusteista ja mahdollisuuksista
2007
Teachers' instructional scaffolding in an innovative information and communication technology-based history learning environment
2002
Abstract The nature of the role assumed by the teacher is crucial in the promotion of successful learning and collaboration in Information and Communication Technologybased (ICT-based) environments. The aim of this study was to examine how teachers with different conceptions of their teacher roles use different types of instructional scaffolding while working in an innovative learning environment. Our further aim was finding out how instructional scaffolding is related to learning activities of different kinds. The study was carried out at two secondary schools with a shared network-based learning environment. The results showed that teachers with different conceptions of the teacher's role…
A multicompartment model for open-loop control of glucose in insulin-dependent diabetics
1990
This paper describes a model that has been developed for individually adjusted therapy management in insulin-dependent diabetics. The multicompartment model considers all relevant aspects of glucose kinetics and its dependence on insulin. The structure of the model reflects that of the physiological system. Its parameters can be classified into (a) general parameters that are independent of the individual, (b) classifying parameters that are related systematically to the individual, and (c) distinguishing parameters. Classifying parameters allow a very convenient adjustment to relevant features of the individual like sex, age, body weight and length. The model can be employed in open-loop c…
Real-time estimation of plasma insulin concentration from continuous glucose monitor measurements
2015
Continuous glucose monitors can measure interstitial glucose concentration in real time for closed-loop glucose control systems, known as artificial pancreas. These control systems use an insulin feedback to maintain plasma glucose concentration within a narrow and safe range, and thus to avoid health complications. As it is not possible to measure plasma insulin concentration in real time, insulin models have been used in literature to estimate them. Nevertheless, the significant interand intra-patient variability of insulin absorption jeopardizes the accuracy of these estimations. In order to reduce these limitations, our objective is to perform a real-time estimation of plasma insulin co…
The efficacy and safety of ezetimibe/simvastatin combination compared with intensified lipid-lowering treatment strategies in diabetic subjects with …
2012
Aims The objective was to assess the consistency of effect of switching to ezetimibe/simvastatin 10/20 mg versus doubling the baseline statin dose (to simvastatin 40 mg or atorvastatin 20 mg) or switching to rosuvastatin 10 mg across subgroups of subjects with (n = 617) and without (n = 191) metabolic syndrome (MetS). Methods This was a post hoc analysis of a randomized, double-blind, 6-week study of adults 18–79 years with cardiovascular disease and diabetes mellitus with low-density lipoprotein cholesterol (LDL-C) ≥70 and ≤160 mg/dl. The percent change in LDL-C and other lipids was estimated within each subgroup separately. Safety and tolerability were assessed. Results In subjects with M…
Biosimilars and Novel Insulins.
2019
Background Insulin therapy is the mainstay of treatment for type 1 diabetes and may be necessary in type 2 diabetes. Current insulin analogues present a more physiological profile, are effective, and with less risk of hypoglycemia, but they are expensive. Biosimilar insulins should offer the advantages of insulin analogues at reduced costs. In addition, current rapid-acting insulin analogues are not fast enough to control excessive postprandial glucose excursions in many patients. Areas of uncertainty Biosimilar insulins demonstrated that are safe and effective, but interchangeability and automatic substitution remain an issue. Ultrafast-acting insulins should reduce postprandial hyperglyce…
Connectivity percolation in suspensions of hard platelets
2012
We present a study on connectivity percolation in suspensions of hard platelets by means of Monte Carlo simulation. We interpret our results using a contact-volume argument based on an effective single--particle cell model. It is commonly assumed that the percolation threshold of anisotropic objects scales as their inverse aspect ratio. While this rule has been shown to hold for rod-like particles, we find that for hard plate-like particles the percolation threshold is non-monotonic in the aspect ratio. It exhibits a shallow minimum at intermediate aspect ratios and then saturates to a constant value. This effect is caused by the isotropic-nematic transition pre-empting the percolation tran…
Konsolidācija Aktīvu pārvaldīšanas nozarē un ietekme uz darbības procesiem
2018
Finanšu pakalpojumu vide neapšaubāmi ir ļoti mainīga un tuvākajos gados Aktīvu Pārvaldes nozarē būs nopietnas radikālās izmaiņas. Regulatori un tehnoloģijas attīstība veicina finansiālu sistēmu uz lielajām pārmaiņām. Pēdējos gados palielinājās ieguldījumu plūsma kompānijām, kas izmanto vienīgu apstrādes programmu, ar apkopoto datu analīzi. Tajā mākslīgais intelekts palīdz interpretēt finansiālo informāciju. Ar minētajām izmaiņām aktīvu pārvaldes dalībniekiem būs jāveido virkne jaunu analītisko rīku, jo cilvēki nebūs spējīgi apstrādāt visus datus patstāvīgi. Esošais cilvēka un mašīnas līdzsvars, turpinās noliekties vairāk un vairāk uz mašīnas pusēs, kamēr cilvēks gandrīz pilnīgi būs aizvieto…
A double mean field equation related to a curvature prescription problem
2019
We study a double mean field-type PDE related to a prescribed curvature problem on compacts surfaces with boundary. We provide a general blow-up analysis, then a Moser-Trudinger inequality, which gives energy-minimizing solutions for some range of parameters. Finally, we provide existence of min-max solutions for a wider range of parameters, which is dense in the plane if $��$ is not simply connected.
Three Step Bluetooth Positioning
2005
This paper discusses a three step procedure to perform high definition positioning by the use of low cost Bluetooth devices. The three steps are: Sampling, Deployment, and Real Time Positioning. A genetic algorithm is discussed for deployment optimization and a neural network for real time positioning. A case study, along with experiments and results, are finally discussed dealing with a castle in Sicily where many trials were carried out to the end of arranging a positioning system for context aware service provision to visitors.