Search results for "SITU"
showing 10 items of 1824 documents
Array CGH defined interstitial deletion on chromosome 14: a new case
2009
Interstitial deletions of the long arm of chromosome 14 are relatively rare. We report a 8.5-year-old girl with dysmorphic facial features and mental retardation associated with a de novo interstitial deletion of chromosome 14. The comparison between our patient and all published patients is reviewed. The genetic investigations have allowed us to define the critical chromosomal region and to start an accurate follow-up.
Expression Patterns and Subcellular Localization of Carbonic Anhydrases Are Developmentally Regulated during Tooth Formation
2014
Abstract Carbonic anhydrases (CAs) play fundamental roles in several physiological events, and emerging evidence points at their involvement in an array of disorders, including cancer. The expression of CAs in the different cells of teeth is unknown, let alone their expression patterns during odontogenesis. As a first step towards understanding the role of CAs during odontogenesis, we used immunohistochemistry, histochemistry and in situ hybridization to reveal hitherto unknown dynamic distribution patterns of eight CAs in mice. The most salient findings include expression of CAII/Car2 not only in maturation-stage ameloblasts (MA) but also in the papillary layer, dental papilla mesenchyme, …
“BEP” RNAs and Proteins Are Situated in the Animal Side of Sea Urchin Unfertilized Egg, Which Can Be Recognized by Female Pronuclear Localization
1996
Microsurgery experiments demonstrate that the animal side of the unfertilized sea urchin Paracentrotus lividus egg coincides with the side of the egg pronucleus location. It is demonstrated by means of in situ hybridization and immunostaining of whole mounts of animal or vegetal halves that the previously identified bep 1 and bep4 RNAs and their proteins are located in the animal part of the unfertilized egg and much less in the vegetal part. The addition of Fabs against BEP1 and BEP4 causes exogastrulation.
Predictors of residual T1 high grade on re-transurethral resection in a large multi-institutional cohort of patients with primary T1 high-grade/grade…
2018
The aim of this multi-institutional study was to identify predictors of residual high-grade (HG) disease at re-transurethral resection (reTUR) in a large cohort of primary T1 HG/Grade 3 (G3) bladder cancer patients. A total of 1155 patients with primary T1 HG/G3 bladder cancer from 13 academic institutions that underwent a reTUR within 6 weeks after first TUR were evaluated. Logistic regression analysis was performed to assess the association of predictive factors with residual HG at reTUR. Residual HG cancer was found in 288 (24.9%) of patients at reTUR. Patients presenting residual HG cancer were more likely to have carcinoma in situ (CIS) at first resection (p=25 kg/m2. On multivariable …
Beneficial Effect of Docosahexanoic Acid and Lutein on Retinal Structural, Metabolic, and Functional Abnormalities in Diabetic Rats
2009
To assess the effect of docosahexanoic acid (DHA) and lutein (both compounds with anti-inflammatory and antioxidant properties) on experimental diabetic retinopathy.Male Wistar rats were studied: non-diabetic controls, untreated diabetic controls, and diabetic rats were treated with DHA and lutein or the combination of DHA + insulin and lutein + insulin for 12 weeks. Oxidative stress and inflammatory markers, apoptosis, and functional tests were studied to confirm biochemical and functional changes in the retina of diabetic rats. Malondialdehyde (MDA), glutathione concentrations (GSH), and glutathione peroxidase activity (GPx) were measured as oxidative stress markers. TUNEL assay and caspa…
Caspase-dependent cell death involved in brain damage after acute subdural hematoma in rats
2006
Abstract Traumatic brain injury is associated with acute subdural hematoma (ASDH) that worsens outcome. Although early removal of blood can reduce mortality, patients still die or remain disabled after surgery and additional treatments are needed. The blood mass and extravasated blood induce pathomechanisms such as high intracranial pressure (ICP), ischemia, apoptosis and inflammation which lead to acute as well as delayed cell death. Only little is known about the basis of delayed cell death in this type of injury. Thus, the purpose of the study was to investigate to which extent caspase-dependent intracellular processes are involved in the lesion development after ASDH in rats. A volume o…
Degradation of stone materials in the archaeological context of the Greek-Roman Theatre in Taormina (Sicily, Italy)
2010
In the present work results on the degradation phenomena of stone materials in the Ancient Theatre of Taormina, one of the most important Greek–Roman monuments of Sicily, are reported. Artificial stone materials in different conservation conditions were investigated. Samples of salt efflorescences from brick walls and degraded setting mortars were taken from the open gallery in “summa cavea”. The chemical, physical and structural characterization was performed by means of X-Ray Photoelectron Spectroscopy (XPS), X-Ray Diffraction (XRD) and X-Ray Fluorescence (XRF), both in situ and ex situ. Results showed that the deterioration of stone materials is due to the aggressive action of the enviro…
Microwave and optical data fusion for global mapping of soil moisture at high resolution
2018
After more than 8 years in orbit the Soil Moisture and Ocean Salinity (SMOS) satellite is still in good health and several algorithms for improving its spatial resolution have been proposed and validated in a variety of catchments. However, none of them has yet been applied at the global scale. In this article we present: i) a review of the latest SMOS-BEC downscaling algorithm, which allows for its global application using an adaptive moving window and ii) a thorough validation of the resulting maps over two in-situ networks: REMEDHUS in Spain and OzNet in Australia. The proposed algorithm combines SMOS brightness temperatures (at ~40 km spatial resolution), and MODIS-derived Land Surface …
Bēgļu izraidīšanas vai atgriešanas aizlieguma eksteritoriālais raksturs atklātajā jūrā kā starptautiskā paražu tiesību norma
2019
Darbā tiek aplūkota bēgļu izraidīšanas vai atgriešanas aizlieguma teritoriālā piemērojamība, izvērtējot tā darbību ārpus valstu robežām atklātajā jūrā. Saistībā ar bēgļu ierašanās pa jūru izpausmi mūdienās, īpaši nozīmīga ir bēgļu izraidīšanas vai atgriešanas aizlieguma attiecināmība uz masveida pieplūduma situācijām. Vienlaikus būtiski ir arī aplūkot vajāšanas satura paplašināšanos mūsdienās, izvērtējot gan tiesu praksi, gan tā mijiedarbību ar cilvēktiesībām. Tālāk tiek izvērtēta trešās drošās valsts koncepta nozīme bēgļu izraidīšanas vai atgriešanas piemērošanas robežu noteikšanā. Savukārt darba beigās autore analizē bēgļu izraidīšanas vai atgriešanas eksteritoriālo piemērojamību atklātaj…
Relationship between score and coaches’ verbal behavior
2013
Calpe V, Guzman J, Grijalbo C. Relationship between score and coaches’ verbal behaviour. J. Hum. Sport Exerc. Vol. 8, No. Proc3, pp. S728-S737, 2013. The way the coach act the most during the development of the game is meanwhile verbal behaviour directed to their players (Moreno et al., 2000), being it influenced by his own cognitions, motivations, and emotions, together with players behaviours and playing situation (Borrie, 1996; Smoll & Smith, 1989). The aim of this study was to analyse the relationship between a situational variable, the score during the game, and verbal behaviour of handball coaches in competitive situation. To do this, five coaches were analysed in five games. Two vari…