Search results for "SIZE"

showing 10 items of 2718 documents

Factors affecting recurrence and progression in superficial bladder tumours

1995

Prognostic factors in superficial bladder tumours are highly correlated with each other. In this study, their relative importance is examined and grouping of patients in three different prognostic groups suggested. 576 patients (from EORTC protocols 30790 and 30782) were analysed. They have been followed from 3 months to 8.6 years with a median of 4 years. 76 patients developed an invasive tumour (or = T2); the shortest time to invasion was 12 weeks, the longest was 6.6 years. Time from invasion to death ranged from 3 weeks to 4.4 years with a median of 2 years. Prognostic factors contributing to recurrence, invasion and survival were investigated: age, sex, size of largest tumour, number o…

AdultMaleOncologyCancer Researchmedicine.medical_specialtyTime FactorsMultivariate analysisAdolescentMalignant diseaseRisk groupsRisk FactorsInternal medicinemedicineCarcinomaHumansNeoplasm InvasivenessIn patientSurvival rateAgedAged 80 and overAnalysis of VarianceCarcinoma Transitional Cellbusiness.industryMiddle AgedPrognosismedicine.diseaseSurgerySurvival RateTransitional cell carcinomaUrinary Bladder NeoplasmsOncologyTumour sizeDisease ProgressionFemaleNeoplasm Recurrence LocalbusinessFollow-Up StudiesEuropean Journal of Cancer
researchProduct

Association of functional DBH genetic variants with alcohol dependence risk and related depression and suicide attempt phenotypes: Results from a lar…

2012

Abstract Objective Dopamine-beta-hydroxylase (DBH) metabolizes the conversion of dopamine to noradrenaline. DBH, located on chromosome 9q34.2 has variants with potential functional consequences which may be related to alterations of neurotransmitter function and several psychiatric phenotypes, including alcohol dependence (AD), depression (MD) and suicidal behavior (SA). The aim of this association study in a large multicenter sample of alcohol-dependent individuals and controls is to investigate the role of DBH SNPs and haplotypes in AD risk and associated phenotypes (AD with MD or SA). Method 1606 inpatient subjects with DSM-IV AD from four addiction treatment centers and 1866 control sub…

AdultMaleOncologymedicine.medical_specialtyGenotypePoison controlSuicide AttemptedSingle-nucleotide polymorphismDopamine beta-HydroxylaseToxicologyPolymorphism Single NucleotideRisk AssessmentLinkage DisequilibriumGermanyInternal medicinemedicineHumansSNPPharmacology (medical)Age of OnsetDepression (differential diagnoses)PharmacologyDepressive DisorderSex CharacteristicsSuicide attemptAlcohol dependenceHaplotypeDNAMiddle AgedAlcoholismPsychiatry and Mental healthPhenotypeCase-Control StudiesSample SizeEtiologyFemalePsychologyGenome-Wide Association StudyClinical psychologyDrug and Alcohol Dependence
researchProduct

Effect of phenylephrine on static and dynamic accommodation

2018

Purpose We tested the hypothesis that changes in accommodation after instillation of Phenylephrine Hydrochloride (PHCl) observed in some studies could be caused by changes in optics. Methods We performed two experiments to test the effects of PHCl on static and on dynamic accommodation in 8 and 6 subjects, respectively. Objective wavefront measurements were recorded of the static accommodation response to a stimulus at different distances or dynamic accommodation response to a sinusoidally moving stimulus (between 1 and 3 D of accommodative demand at 0.2 Hz). The responses were characterized using two methods: one that takes into account the mydriatic optical effects on the accommodation pr…

AdultMaleOriginal articleAccommodationMydriaticsmedicine.medical_specialtygenetic structuresPhenylephrine03 medical and health sciences0302 clinical medicineCiliary bodyOphthalmologymedicineHumansAcomodaciónPhenylephrineMathematicsbusiness.industryCiliary BodyMétricaPupil sizeAccommodation OcularPhenylephrine Hydrochlorideeye diseasesCiliary musclemedicine.anatomical_structure030221 ophthalmology & optometryMetricsFemalesense organsbusinessFenilefrinaAccommodation030217 neurology & neurosurgeryOptometrymedicine.drugJournal of Optometry
researchProduct

Effectiveness of lingual versus labial fixed appliances in adults according to the Peer Assessment Rating index.

2019

Introduction: The purpose of this study was to compare the effectiveness of lingual treatment and labial fixed appliances in the treatment of adult orthodontic patients. Methods: We conducted a retrospective study of 72 patients. The Peer Assessment Rating (PAR) index was measured at the start (T0) and end (T1) of treatment. Significant differences between treatment means were determined by means of analysis of variancewith the Bonferroni correction or with the use of Fisher exact test. Results: The lingual group had a mean pretreatment age of 28.6 ± 6.7 years, and the labial group had a pretreatment age of 26.6 ± 9.5 years. This difference was statistically not significant. The mean pre- a…

AdultMaleOrthodontic Appliances FixedTreatment outcomeInvestigación médicaOdontologíaOrthodontics03 medical and health sciencessymbols.namesake0302 clinical medicinestomatognathic systemMedicineHumansOrthodontic Appliance DesignAparatos ortodóncicos fijosFisher's exact testRetrospective StudiesOrthodonticsbusiness.industryRetrospective cohort study030206 dentistryPeer Review Health CareOrtodonciastomatognathic diseasesBonferroni correctionTreatment OutcomeSample size determinationsymbolsFemalebusiness030217 neurology & neurosurgeryAmerican journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics
researchProduct

Habituation and short-term repeatability of thermal testing in healthy human subjects and patients with chronic non-neuropathic pain

2008

We investigated habituation effects during thermal quantitative sensory testing (tQST) using 8 repetitive measurements for thermal detection and pain thresholds. The same measurements were repeated two days later. 39 healthy subjects and 36 patients with chronic non-neuropathic pain syndromes (migraine, tension-type headache, non-radicular back pain) were enrolled. The pain intensity was assessed using an 11-point (0-10) numerical rating scale. Measurements correlated significantly over the two days in both groups (r=0.41...0.62). Warm detection (WDT) and heat pain threshold (HPT) revealed no significant differences over these days. Cold detection (CDT) and pain thresholds (CPT) showed sign…

AdultMalePain ThresholdHot TemperaturePainYoung AdultRating scaleSurveys and QuestionnairesmedicineBack painHumansClinical significanceHabituationHabituation PsychophysiologicAgedPain MeasurementReproducibility of ResultsRepeatabilityMiddle Agedmedicine.diseasePeripheralAnesthesiology and Pain MedicineMigraineSample SizeAnesthesiaChronic DiseaseNeuropathic painFemalemedicine.symptomPsychologyEuropean Journal of Pain
researchProduct

How much Is needed? Comparison of the effectiveness of different pain education dosages in patients with fibromyalgia

2019

AbstractObjectiveTo assess the effect of different dosages of pain neuroscience education (PNE) programs on central nociceptive processing in patients with fibromyalgia. Second, to compare the effects of different dosages of PNE programs on numerical pain rating scale (NPRS), disability, and psychological variables.DesignSingle-blind randomized controlled trial.SettingThree fibromyalgia centers in Spain (Valencia, Alcorcón, Alcalá de Henares).SubjectsSeventy-seven patients with fibromyalgia.MethodsParticipants were randomized to four groups of PNE: 1) high-dose PNE (N = 20), 2) low–concentrated dose PNE (N = 20), 3) diluted low-dose PNE (N = 20), and (4) control treatment (N = 17), conducte…

AdultMalePain Thresholdmedicine.medical_specialtyFibromyalgiaTime FactorsDoseAnxietylaw.invention03 medical and health sciences0302 clinical medicinePatient Education as TopicRandomized controlled trial030202 anesthesiologylawFibromyalgiaPressuremedicineHumansSingle-Blind MethodIn patientAgedPain MeasurementControl treatmentbusiness.industryCatastrophizationLarge effect sizeDiffuse noxious inhibitory controlPain PerceptionGeneral MedicineMiddle Agedmedicine.diseasePostsynaptic Potential SummationAnesthesiology and Pain MedicinePhysical therapyFemalePain catastrophizingNeurology (clinical)Human medicinebusiness030217 neurology & neurosurgeryPain medicine
researchProduct

Body size at birth and coronary heart disease-related hospital care in adult men : Findings from the Helsinki Birth Cohort Study

2017

Aim: We investigated, among those who had been hospitalized at least once due to coronary heart disease (CHD), the relationship between ponderal index (PI, birthweight/length3) at birth, a measure of thinness, and the age at first hospitalization due to CHD, the number of CHD-related hospital care episodes, and cost of CHD-related hospital care from young adulthood to old age. Methods and results: Data from the Helsinki Birth Cohort Study included 964 men born in Helsinki, Finland during 1934–1944, who had been hospitalized due to CHD and had birth anthropometrics data. PI (kg/m3) was categorized into low (27.5). CHD-related hospital care data were available from 1971 to 2013. We observed a…

AdultMalePediatricsmedicine.medical_specialtyBirth weightCoronary Disease030204 cardiovascular system & hematologyRate ratioCohort Studies03 medical and health sciences0302 clinical medicineage of onsetThinnesscardiovascular disease030225 pediatricsPrevalenceBirth WeightBody SizeHumansMedicinecardiovascular diseasesYoung adultcoronary heart diseaseFinlandbusiness.industryagingta3141General Medicineta3142AnthropometryConfidence intervalCoronary heart disease3. Good healthHospitalizationbirthweightAge of onsetbusinessCohort studyAnnals of Medicine
researchProduct

Long-term health effects on the next generation of Ramadan fasting during pregnancy

2011

Each year, many pregnant women fast from dawn to sunset during the Islamic holy month of Ramadan. Medical theory suggests that this may have negative long-term health effects on their offspring. Building upon the work of Almond and Mazumder (2008), and using Indonesian crosssectional data, I show that people who were exposed to Ramadan fasting during their mother's pregnancy have a poorer general health and are sick more often than people who were not exposed. This effect is especially pronounced among older people, who, when exposed, also report health problems more often that are indicative of coronary heart problems and type 2 diabetes. The exposed are a bit smaller in body size and weig…

AdultMalePediatricsmedicine.medical_specialtyOffspringCross-sectional studyHealth StatusMothersType 2 diabetesBody sizeIslamYoung AdultHealth problemsSDG 3 - Good Health and Well-beingjel:I2PregnancymedicineHumansYoung adultFamily CharacteristicsPregnancybusiness.industryHealth PolicyPublic Health Environmental and Occupational HealthFastingMedical theorymedicine.diseasehealth Ramadan pregnancy nutrition IndonesiaPregnancy Complicationsjel:J1jel:J14Cross-Sectional Studiesjel:I12Socioeconomic FactorsPrenatal Exposure Delayed EffectsIndonesiaPrenatal Exposure Delayed Effects/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemaleGeneral healthbusinessOlder peopleDemographyhealth; Ramadan; pregnancy; nutrition; Indonesia
researchProduct

Prenatal head growth and child neuropsychological development at age 14 months

2014

We sought to assess the association between prenatal head growth and child neuropsychological development in the general population.We evaluated 2104 children at the age of 14 months from a population-based birth cohort in Spain. Head circumference (HC) was measured by ultrasound examinations at weeks 12, 20, and 34 of gestation and by a nurse at birth. Head growth was assessed using conditional SD scores between weeks 12-20 and 20-34. Trained psychologists assessed neuropsychological functioning using the Bayley Scales of Infant Development. Head size measurements at birth were transformed into a 3-category variable: microcephalic (10th percentile), normocephalic (≥10th and90th percentile)…

AdultMalePediatricsmedicine.medical_specialtyPopulationBayley Scales of Infant DevelopmentUltrasonography PrenatalCohort StudiesChild DevelopmentCognitionPregnancymedicineHumanseducationPsychomotor learningPregnancyeducation.field_of_studybusiness.industryInfant NewbornInfantObstetrics and GynecologyOrgan Sizemedicine.diseaseChild developmentMegalencephalyConfidence intervalMicrocephalyGestationFemalebusinessHeadCohort studyAmerican Journal of Obstetrics and Gynecology
researchProduct

Tooth size changes with age in a Spanish population: Percentile tables

2010

Objectives: The aims of this work were: firstly, to draw up tables of percentile tooth sizes similar to those of Sanin and Savara for three age groups of a Spanish population; secondly, to describe changes in tooth size between those groups over time, as well as observing any sexual dimorphism and, finally, to compare both the Spanish and Sanin and Savara's American population samples. Material and methods: The sample included 359 patients and was divided into three age groups: adolescents, young adults and adults, of both genders. After dental cast digitalization, mesiodistal tooth-size was measured on each dental cast using a digital method. Dental size tables organized by percentiles for…

AdultMalePercentileAdolescentDentistryAge and genderYoung Adultstomatognathic systemAge groupsHumansOdontometryMedicineAmerican populationGrowth ChartsDental castTOOTH SIZEYoung adultChildGeneral Dentistrybusiness.industryAge FactorsOrgan SizeMiddle Aged:CIENCIAS MÉDICAS [UNESCO]Spanish populationstomatognathic diseasesOtorhinolaryngologySpainUNESCO::CIENCIAS MÉDICASFemaleSurgerybusinessToothDemographyMedicina Oral Patología Oral y Cirugia Bucal
researchProduct