Search results for "SJ"
showing 10 items of 2539 documents
Invariant NKT cells are expanded in peripheral blood but are undetectable in salivary glands of patients with primary Sjögren's syndrome
2016
OBJECTIVES: Invariant NKT (iNKT) cells play a role in regulating the function of autoreactive B cells before their entry into germinal centres. Absence and/or reduction of iNKT cells have been demonstrated in patients with systemic lupus erythematosus (SLE) together with an increase of autoreactive B cell activity. Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease in which lymphocyte infiltration and organisation in lymphoid structures of inflamed salivary glands occurs. The aim of the study was to investigate the percentage and function of iNKT in the salivary glands and peripheral blood of patients with pSS. METHODS: Minor salivary gland biopsies were obtained from patient…
Effectiveness of training in guideline-oriented biopsychosocial management of low-back pain in occupational health services – a cluster randomized co…
2021
Objective This study aimed to investigate the effectiveness of brief training in the guideline-oriented biopsychosocial management of low-back pain (LBP) in occupational health services using a cluster-randomized design. A small sample of physiotherapists and physicians from the intervention units (N=12) were given three- to seven-day training focusing on the biopsychosocial management of LBP, while professionals in the control units (N=15) received no such training. Methods Eligible patients with LBP, with or without radicular pain, aged 18-65, were invited to participate. A web-based questionnaire was sent to all recruited patients at baseline, three months and one year. The primary outco…
On the use of Denoising Autoencoders and Deep Convolutional Adversarial Networks for Automated Removal of Date Stamps
2019
Master's thesis Information- and communication technology IKT590 - University of Agder 2019 This thesis investigates to what extent the deep learning models such as DenoisingAutoencoder (DAE) and Deep Convolution General Adversarial Net (DCGAN)automate the removal of the date stamps from images with high resolution whilepreserving the rest of the images. Both DAE and DCGAN algorithms are im-plemented with Convolutional Neural Networks (CNN). The DAE algorithm canperform this task with entirely satisfactory results. The DAE can reconstruct theoriginal images from corrupted inputs with date stamps. While DCGAN deliverspoor yet interesting results. The images generated by the DCGAN are quite d…
Determinants of Blockchain Technology Introduction in Organizations: an Empirical Study among Experienced Practitioners
2021
Abstract Blockchain is expected to enable new types of interorganizational relationships, new approaches to governance and new approaches to settlement and clearing processes. Neverthless, although the interest on blockchain is on the rise, there are not many blockchain implementations in organizations and there is limited empirical research investigating the reasons for this. This paper contributes to filling this gap by investigating the following research question: what are the impeding and motivating factors for organizational blockchain adoption? Data were collected through a survey based on pairwise comparisons of key factors identified in the literature. The data collected were analy…
A peptide from the staphylococcal protein Efb binds P‐selectin and inhibits the interaction of platelets with leukocytes
2022
AimsP-selectin is a key surface adhesion molecule for the interaction of platelets with leukocytes. We have shown previously that the N-terminal domain of S. aureus extracellular fibrinogen-binding protein (Efb) binds to P-selectin and interferes with platelet-leukocyte aggregate formation. Here, we aimed to identify the minimal Efb motif required for binding platelets and to characterise its ability to interfering with the formation of platelet-leukocyte aggregates.Methods and ResultsUsing a library of synthetic peptides, we mapped the platelet-binding site to a continuous 20 amino acid stretch. The peptide Efb68-87 was able to bind to resting and, to a greater extent, thrombin-stimulated …
Tietojärjestelmän käyttöönoton kriittiset menestystekijät logistiikkakeskuksessa : tapaustutkimus
2017
Liiketoiminta muuttuu jatkuvasti kustannustehokkaammaksi ja nopeatempoisemmaksi. Toimintoja tehostetaan ja säästöjä pyritään löytämään kaikista mahdollisista kohteista. Tietojärjestelmiä kehitetään helpottamaan ja nopeuttamaan liiketoimintaa. Yritykset investoivatkin runsaasti uusiin tietojärjestelmiin. Tietojärjestelmien ja varsinkin ERP-järjestelmien käyttöönotot ovat kuitenkin vaativia projekteja. ERP-järjestelmä on integroitu moduuleista koostuva tietojärjestelmä, joka käyttää organisaation yhteisiä tietokantoja. Kohdeyrityksessä eli keskisuuressa logistiikkakeskuksessa oli haasteita aiemman tietojärjestelmän käyttöönoton yhteydessä, joten nyt lähdettiin laatimaan ohjeistusta tulevan ER…
Uniqueness and reconstruction for the fractional Calder\'on problem with a single measurement
2020
We show global uniqueness in the fractional Calder\'on problem with a single measurement and with data on arbitrary, possibly disjoint subsets of the exterior. The previous work \cite{GhoshSaloUhlmann} considered the case of infinitely many measurements. The method is again based on the strong uniqueness properties for the fractional equation, this time combined with a unique continuation principle from sets of measure zero. We also give a constructive procedure for determining an unknown potential from a single exterior measurement, based on constructive versions of the unique continuation result that involve different regularization schemes.
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
2010
We undertook a meta-analysis of six Crohn's disease genome-wide association studies (GWAS) comprising 6,333 affected individuals (cases) and 15,056 controls and followed up the top association signals in 15,694 cases, 14,026 controls and 414 parent-offspring trios. We identified 30 new susceptibility loci meeting genome-wide significance (P < 5 x 10(-8)). A series of in silico analyses highlighted particular genes within these loci and, together with manual curation, implicated functionally interesting candidate genes including SMAD3, ERAP2, IL10, IL2RA, TYK2, FUT2, DNMT3A, DENND1B, BACH2 and TAGAP. Combined with previously confirmed loci, these results identify 71 distinct loci with gen…
A continuous decomposition of the Menger curve into pseudo-arcs
2000
It is proved that the Menger universal curve M admits a continuous decomposition into pseudo-arcs with the quotient space homeomorphic to M. Wilson proved [8] Anderson's announcement [1] saying that for any Peano continuum X the Menger universal curve M admits a continuous decomposition into homeomorphic copies of M such that the quotient space is homeomorphic to X. Anderson also announced (unpublished) that the plane admits a continuous decomposition into pseudo-arcs. This result was proved by Lewis and Walsh [4]. In a previous paper [6] the author has proved that each locally planar Peano continuum with no local separating point admits a continuous decomposition into pseudo-arcs. Applying…
Micromorphological observations on leaf and pollen ofCapparisL. sect.Capparis(Capparaceae)
2004
Sect. Capparis is represented by a single species, Capparis spinosa L., divided into several intraspecific taxa showing plesiomorphic features and disjunct distributions in the Old World. Leaf surface and pollen features were investigated in the whole group by SEM and light microscope observations. The section is characterized by simple hairs, a reticulate to undulate cuticle, anomocytic stomata surrounded by a peristomal rim, and trizonocolporate, prolate pollen grains. The characteristics of the indumentum appear constant, while the studied taxa are fairly differentiated with respect to cuticular patterns and dimensions of the stomata, and show slight differences in pollen size and exine …