Search results for "SKIN"
showing 10 items of 3630 documents
In Vitro and In Vivo Regulation of SRD5A mRNA Expression of Supercritical Carbon Dioxide Extract from Asparagus racemosus Willd. Root as Anti-Sebum a…
2022
Oily skin from overactive sebaceous glands affects self-confidence and personality. There is report of an association between steroid 5-alpha reductase gene (SRD5A) expression and facial sebum production. There is no study of the effect of Asparagus racemosus Willd. root extract on the regulation of SRD5A mRNA expression and anti-sebum efficacy. This study extracted A. racemosus using the supercritical carbon dioxide fluid technique with ethanol and investigated its biological compounds and activities. The A. racemosus root extract had a high content of polyphenolic compounds, including quercetin, naringenin, and p-coumaric acid, and DPPH scavenging activity comparable to that of the standa…
Leishmaniasis, contact hypersensitivity and graft-versus-host disease: understanding the role of dendritic cell subsets in balancing skin immunity an…
2010
Dendritic cells (DC) are key elements of the immune system. In peripheral tissues, they function as sentinels taking up and processing antigens. After migration to the draining lymph nodes, the DC either present antigenic peptides by themselves or transfer them to lymph node-resident DC. The skin is the primary interface between the body and the environment and host's various DC subsets, including dermal DC (dDC) and Langerhans cells (LC). Because of their anatomical position in the epidermis, LC are believed to be responsible for induction of adaptive cutaneous immune responses. The functions of LC and dDC in the skin immune system in vivo are manifold, and it is still discussed controvers…
Determination of the atmospheric precipitation pH value on the basis of the analysis of lichen cationoactive layer constitution
2006
Studies of equilibria and kinetics of the ion exchange process between the surrounding (water solution) and lichens prove that the number of mobile hydrogen ions bonded in lichens depends on the concentration of hydrogen ions in the precipitation with which the lichens are in contact and the type and concentration of other cations contained in the precipitation. The measurement of these values was suggested; as a result, it enabled to determine the pH of precipitation by determination of mobile cations bonded in exposed or naturally grown lichens. The studies were conducted on Hypogymnia physodes lichens.
"Table 3" of "Search for supersymmetry with jets, missing transverse momentum and at least one hadronically decaying $\tau$ lepton in proton-proton c…
2012
Distribution of the effective mass before final selection requirement on the effective mass. Tabulated are the observed Data events, the Standard Model predictions and the expected rates for two signal scenarios with Lambda=30TeV / tan(beta) = 20 and Lambda=40GeV / tan(beta)=30 respectively.
Determination of reflectance spectra model of skin phototypes V
2012
In dermatology, skin is assessed for its response to UV light and is categorised under the Fitzpatrick skin type (FST). The FST is commonly applied as a predictor of skin cancer. The FST classification however is subjective. To enable an objective assessment, a pattern model of skin colour taken from normal subjects is required. In this paper, a model for skin phototype (SPT) V is developed and presented. We conducted an observational study involving 41 participants with FST V. The study analysed the reflectance spectra of facultative skin and constitutive skin which was captured using spectrophotometer and multispectral camera. Using piecewise linear regression, we modelled the reflectance…
Mechanical parameters identification of keloid and surrounding healthy skin using Digital Image Correlation measurements in vivo
2019
International audience; The human skin behaves as an elastic membrane initially prestressed but not uniformly. The presence of anatomical sites favorable to the appearance of some tumors, a keloid in our case, while other sites never develop them attests to the importance of the mechanical environment of the tissue. Thus, a mechanical characterization of the tumored skin is necessary to understand the keloid expansion from a mechanical point of view. Our case study consists in modeling a bi-material structure composed of a keloid skin surrounded by healthy skin located on upper left arm of a young female. From the experimental measurements in vivo, by combining force sensor, displacement se…
Magnetofection of acoustically active „magnetic microspheres“ (Magnetobubbles) — Induction of angiogenesis via non-viral transfection of VEGF
2009
Adenoviral transduction of the VEGF gene in an oversized skin flap increases flap survival and perfusion. In this study we investigated the potential of magnetofection of magnetic lipospheres containing VEGF165-cDNA on survival and perfusion of ischemic skin flaps and evaluated the method with respect to the significance of applied magnetic field and ultrasound.
Experimentelle Bestimmung der Gleitreibungskräfte beim Einschlagen von Oberschenkelmarknägeln
1990
No data have published concerning the procedure of driving in intramedullary nails. An extensive experimental device consisting of a contact-free distance measurement, a dynamograph connected to strain gages and an accelerometer now enabled this investigation. Among other things we determined the range of sliding friction for each stroke at different levels of nail-progression. Depending of the depth of nail-progression forces between 200 N und 400 N were measured. When the nail is stuck these values rise to over 1000 N. The sliding-process lasted between 10 ms and 20 ms. Knowledge of these data is of major importance for improvement of surgical technique and possible development of mechani…
Melanin type and concentration determination using inverse model
2011
Abnormality of melanin production causes skin pigmentation disorders. Currently, assessment of treatment efficacy (under Physician's Global Assessment framework) only refers to visual conditions of skin surface and not the condition of the underlying skin layers and pigments. Albeit researches on models and simulations of light interaction with human skin have been reported, none has been specifically developed for pigmentation analysis of melanin types - eumelanin and pheomelanin. Therefore, our research objectives are to develop image analysis of skin pigmentation for classification and quantification of eumelanin and pheomelanin pigment types in human skin. In this research, the model is…
The Fundamental Role of Melanocortins in Brain Processes
2003
The discoveries of the latest ten years have shed new light in understanding the roles of melanocortins and their receptors in brain functions and in the development of different pathologies. Since 1992 when genes encoded melanocortin receptor five subtypes were identified, cloned and characterized, the molecular mechanisms underlying different effects such as skin darkening, behaviour, food intake, anti-inflammatory action, analgesia have been clarified. The contribution of melanocortins and their receptors in the physiological control of organism homeostasis has become as the background for the search of agonists and antagonists of separate receptor subtypes, that can be targeted to the m…