Search results for "SLI"
showing 10 items of 1729 documents
Zur Morphologie des embryonalen Meckelschen Knorpels der Vögel [Putnu embrionālā Meckela skrimšļa morfoloģija]
1933
Teksts vācu valodā, kopsavilkums latviešu valodā.
No zoba pulpas cilmes šūnām izolētu eksosomu ietekme uz dzīvnieku gaitu 6-hidroksidopamīna inducētā Pārkinsona slimības modelī žurkās
2019
Pārkinsona slimība ir otra visbiežāk sastopamā neirodeģeneratīvā saslimšana pasaulē, kuras incidence turpina pieaugt. Slimības pacientiem raksturīgi gaitas traucējumi, kas ļoti ierobežo dzīves kvalitāti. Diemžēl joprojām nav atrasta efektīva medikamentozā terapija, kas apturētu slimības progresiju. Šī darba mērķis bija noskaidrot, vai no zoba pulpas cilmes šūnām izolētas eksosomas reversē gaitas izmaiņas 6-hidroksidopamīna (6-OHDA) inducētā Pārkinsona slimības modelī žurkās, kā arī noskaidrot, vai pēc eksosomu lietošanas pārtraukšanas ir novērojams ilgtermiņa gaitu normalizējošs efekts. Gaitas izmaiņu noteikšanai tika veikts CatWalk XT automatizētais gaitas tests. Darbā iegūtie dati ļauj se…
Akūtas nieru mazspējas gadījumu analīze slimnīcu intensīvās terapijas nodaļās: diagnostikas, terapijas efektivitātes un iznākumu izvērtējums
2015
Darba aktualitāte: mūsdienās akūta nieru mazspēja (ANM) ir relatīvi reta diagnoze stacionētiem pacientiem, jo ir vairākas klasifikācijas, pēc kurām tiek atšķirta akūta nieru slimība, jeb akūta nieru disfunkcija no gala stadijas - akūtas nieru mazspējas. Tomēr kopējais īpatsvars pacientiem ar akūtu nieru disfunkciju Latvijas slimnīcu intensīvās terapijas nodaļās, ir liels. Tā kā akūta nieru mazspēja ir stāvoklis pie kura novēro lielu letalitāti, ir nepieciešams īpaši rūpīgi atlasīt šos pacientus un agrīni preventēt slimības gala stadijas attīstību. Darba mērķis: izanalizēt ANM diagnostikas un terapijas metodes un to ietekmi uz pacientu letalitāti trīs Latvijas slimnīcas intensīvās terapijas …
Prediction of Highly Non-stationary Time Series Using Higher-Order Neural Units
2017
Adaptive predictive models can use conventional and nonconventional neural networks for highly non-stationary time series prediction. However, conventional neural networks present a series of known drawbacks. This paper presents a brief discussion about this concern as well as how the basis of higher-order neural units can overcome some of them; it also describes a sliding window technique alongside the batch optimization technique for capturing the dynamics of non-stationary time series over a Quadratic Neural Unit, a special case of higher-order neural units. Finally, an experimental analysis is presented to demonstrate the effectiveness of the proposed approach.
Analysis of oblique rebound using a redefinition of the coefficient of tangential restitution coefficient
2013
Abstract A redefinition of the coefficient of tangential restitution based on the separation of friction and restitution effects is presented. Using this modified coefficient of tangential restitution and the usual definitions of the coefficients of normal restitution and sliding friction, a description of oblique impacts in both stick and slip regimes is obtained. This, description, which is tested with available rebound data in literature, avoids sharp (apparent) variations in the coefficient tangential restitution with impact angle and can justify anomalous results reported by Calsamiglia et al. (1999) .
Low physical activity and its association with diabetes and other cardiovascular risk factors: a nationwide, population-based study
2016
Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM; ISCIII Ministerio de Ciencia e Innovacion); Ministerio de Sanidad y Consumo; Spanish Diabetes Society (SED)
Crispr gene editing in lipid disorders and atherosclerosis: Mechanisms and opportunities
2021
Elevated circulating concentrations of low-density lipoprotein cholesterol (LDL-C) have been conclusively demonstrated in epidemiological and intervention studies to be causally associated with the development of atherosclerotic cardiovascular disease. Enormous advances in LDL-C reduction have been achieved through the use of statins, and in recent years, through drugs targeting proprotein convertase subtilisin/kexin type 9 (PCSK9), a key regulator of the hepatic LDL-receptor. Existing approaches to PCSK9 targeting have used monoclonal antibodies or RNA interference. Although these approaches do not require daily dosing, as statins do, repeated subcutaneous injections are nevertheless neces…
RUOLO DELLA TOMOGRAFIA COMPUTERIZZATA MULTISLICE NELLA DIAGNOSTICA NON INVASIVA DELLA MALATTIA ATEROSCLEROTICA CORONARICA
2005
Displacement Evolution of a Large Landslide in a Highly Fissured Clay
2019
The paper presents an analysis and modelling of the reactivation mechanism of a large landslide caused by rainfall, located in Cerda (Sicily, Italy). The study is based on data collected by means of a field investigation, carried out in order to assess the geotechnical properties of the involved material, and a three-year monitoring programme implemented to measure rain and pore water pressures as well as deep and superficial displacements. Three distinct landslides, evolving at variable rates in different directions, were recognized within the overall landslide area. The data clearly show the mechanical role of pore water pressures in the stability of the slope and point out the dependence…
Rainfall Induced Landslides in Puerto Rico
2009
Landslides are a major geologic hazard in the United States, typically triggered by rainfall, earthquakes, volcanoes and human activity. Rainfall-induced landslides are the most common type in the island of Puerto Rico, with one or two large events per year. We performed an island-wide determination of static landslide susceptibility and hazard assessment as well as dynamic modeling of rainfall-induced shallow landslides in a particular hydrologic basin. Based on statistical analysis of past landslides, we determined that reliable prediction of the susceptibility to landslides is strongly dependent on the resolution of the digital elevation model (DEM) employed and the reliability of the ra…