Search results for "SNA"
showing 10 items of 628 documents
Familias transnacionales, familias inmigrantes: reflexiones sobre su inclusión en la escuela
2019
El objetivo del presente artículo es describir el impacto que las migraciones tienen en las familias a través de una revisión bibliográfica sobre migración internacional como metodología de trabajo. Se examinaron artículos publicados entre 1998 y 2014 indexados en las bases de datos Web of Science y Scopus. Con el análisis de los artículos seleccionados se construyó un cuerpo teórico desde el cual se presentan los conceptos de familia transnacional, feminización de la migración mundial, concepción de la paternidad, fragmentación de la familia, reagrupación familiar, así como las principales dificultades de las familias migrantes en el país de destino que dan lugar a situaciones de exclusión…
Survival and infectivity of Hypoderaeum conoideum and Euparyphium albuferensis cercariae under laboratory conditions.
1999
The survival characteristics of the cercariae of Hypoderaeumconoideum and Euparyphiumalbuferensis (Trematoda: Echinostomatidae) at 20°C and 30°C are described, and the age dependency of their infectivity at 20°C is studied to determine their respective transmission efficiencies. Cercarial survival was found to be age-dependent and was higher at 20°C. For both cercariae, the maximum life-span was 26 h at 20°C and 16 h at 30°C, and their respective times to 50% mortality were similar at each temperature. Both cercariae seem to be well adapted to transmission in their natural habitat, though cercarial infectivity of H. conoideum was higher than that of E. albuferensis, this being correlated wi…
Equines as reservoirs of human fascioliasis: transmission capacity, epidemiology and pathogenicity inFasciola hepatica-infected mules
2020
AbstractFascioliasis is a zoonotic disease caused by liver flukes transmitted by freshwater lymnaeid snails. Donkey and horse reservoir roles have been highlighted in human endemic areas. Liver fluke infection in mules has received very limited research. Their role in disease transmission, epidemiological importance andFasciola hepaticapathogenicity are studied for the first time. Prevalence was 39.5% in 81 mules from Aconcagua, and 24.4% in 127 from Uspallata, in high-altitude areas of Mendoza province, Argentina. A mean amount of 101,242 eggs/mule/day is estimated. Lymnaeids from Uspallata proved to belong to ribosomal DNA internal transcribed spacer (ITS) markers ITS-1 and ITS-2 combined…
The inhibitor of differentiation-1 (Id1) enables lung cancer liver colonization through activation of an EMT program in tumor cells and establishment…
2017
Abstract: Id1 promotes carcinogenesis and metastasis, and predicts prognosis of non-small cell lung cancer (NSCLC)-adenocarcionoma patients. We hypothesized that Id1 may play a critical role in lung cancer colonization of the liver by affecting both tumor cells and the microenvironment. Depleted levels of Id1 in LLC (Lewis lung carcinoma cells, LLC shId1) significantly reduced cell proliferation and migration in vitro. Genetic loss of Id1 in the host tissue (Id1(-/-) mice) impaired liver colonization and increased survival of Id1 animals. Histologically, the presence of Idl in tumor cells of liver metastasis was responsible for liver colonization. Microarray analysis comparing liver tumor n…
Poly-Gly Region Regulates the Accessibility of Metal Binding Sites in Snake Venom Peptides
2022
It is supposed that the presence of poly-His regions in close proximity to poly-Gly domains in snake venoms is related to their biological activity; poly-His/poly-Gly (pHpG) peptides inhibit the activity of metalloproteinases during venom storage via the chelation metal ions, necessary for their proper functioning. This work shows that only the histidyl residues from the N-terminal VDHDHDH motif (but not from the poly-His tag) were the primary Zn(II) binding sites and that the poly-Gly domain situated in the proximity of a central proline residue may play a regulatory role in venom gland protection. The proline induces a kink of the peptide, resulting in steric hindrance, which may modulate…
Are we any good at protecting our societies and economies from the threat of economic crime and misconduct?
2019
PurposeThis paper aims to outline the Italian framework of rules against economic crime and to verify if Italian legislation provides for appropriate and effective measures according to own needs both at a national and European level.Design/methodology/approachThe paper uses a comparative approach by examining the European and Italian legal systems for finding analogies and differences between them.FindingsThe study has revealed the need of a greater international harmonisation of criminal laws and penalties as well as the transnationality of the economic crime cuts the chance of success of every national strategy, given that transnational criminals are encouraged by the awareness that thei…
Cadenas de suministro, Derechos Humanos, Empresas Transnacionales e industria textil: de los AMI a un Instrumento Internacional Jurídicamente Vincula…
2019
espanolEl texto parte de la necesidad de elaborar normas vinculantes a nivel internacional sobre empresas transnacionales y derechos humanos con la finalidad de poner fin a la impunidad de la que gozan cuando, directamente o a lo largo de los distintos eslabones de su cadena de suministro, provocan violaciones de estos derechos, asi como asegurar la reparacion de las victimas y posibles secuelas. Existen distintas iniciativas en el plano internacional, tanto en el ambito de Naciones Unidas (Principios Rectores) como en el ambito de las propias corporaciones y sus relaciones con los sindicatos (Acuerdos Marco Internacionales), orientadas a impulsar a las empresas transnacionales hacia compor…
Le projet mondial du Kominterm à l’épreuve des réalités nationales. Histoire globale et analyses transnationales
2020
International audience
Introduction. L’Internationale communiste et l’histoire globale
2020
International audience
« Démocrates de tous les pays, unissez-vous » ? La conférence internationale des partis communistes du 21 avril 1937, zénith crépusculaire de l’inter…
2020
International audience