Search results for "SOA"

MMP2 expression in mouse mesoangioblast is dependent on Hsp70 level.

2013

Mesoangioblast behaviour in oxidative stress condition

2010

La regolazione dell’espressione della MMP2 in mesoangioblasti è dipendente dai livelli della proteina Hsp70.

2013

Mesoangioblasti di topo producono e rilasciano nello spazio extracellulare vescicole di membrana contenenti MMP9 e FGF2 in forma attiva

2009

Autocrine role of extracellular Hsp70 in mesoangioblast migration capability

2014

Detailed clinical, genetic and neuroimaging characterization of OFD VI syndrome.

2012

Oral-facial-digital syndrome type VI (OFD VI) is characterized by the association of malformations of the face, oral cavity and extremities, distinguished from the 12 other OFD syndromes by cerebellar and metacarpal abnormalities. Cerebellar malformations in OFD VI have been described as a molar tooth sign (MTS), thus, including OFD VI among the "Joubert syndrome related disorders" (JSRD). OFD VI diagnostic criteria have recently been suggested: MTS and one or more of the following: 1) tongue hamartoma(s) and/or additional frenula and/or upper lip notch; 2) mesoaxial polydactyly of hands or feet; 3) hypothalamic hamartoma. In order to further delineate this rare entity, we present the neuro…

High-density ZnO Nanowires as a Reversible Myogenic-Differentiation-Switch

2018

Mesoangioblasts are outstanding candidates for stem-cell therapy and are already being explored in clinical trials. However, a crucial challenge in regenerative medicine is the limited availability of undifferentiated myogenic progenitor cells because growth is typically accompanied by differentiation. Here reversible myogenic-differentiation switching during proliferation is achieved by functionalizing the glass substrate with high-density ZnO nanowires (NWs). Specifically, mesoangioblasts grown on ZnO NWs present a spherical viable undifferentiated cell state without lamellopodia formation during the entire observation time (8 days). Consistently, the myosin heavy chain, typically express…

Microbial Degradation of 2,4,6-Trinitrotoluene In Vitro and in Natural Environments

2013

2,4,6-Trinitrotoluene (TNT) is a nitroaromatic explosive that was released into soil and water ecosystems mainly due to its massive use during the two world wars.

NANC inhibitory neurotransmission in mouse isolated stomach: Involvement of nitric oxide, ATP and vasoactive intestinal polypeptide

2003

1. The neurotransmitters involved in NANC relaxation and their possible interactions were investigated in mouse isolated stomach, recording the motor responses as changes of endoluminal pressure from whole organ. 2. Field stimulation produced tetrodotoxin-sensitive, frequency-dependent, biphasic responses: rapid transient relaxation followed by a delayed inhibitory component. 3. The inhibitor of the synthesis of nitric oxide (NO), L-NAME, abolished the rapid relaxation and significantly reduced the slow relaxation. Apamin, blocker of Ca 2+-dependent K + channels, or ADPβS, which desensitises P 2y purinoceptors, reduced the slow relaxation to 2-8 Hz, without affecting that to 16-32 Hz or the…

A CONFIGURAÇÃO INOVADORA DO PRINCÍPIO DA BOA ADMINISTRAÇÃO ENTRE PRIVADOS E AUTORIDADES PÚBLICAS NA UNIÃO EUROPÉIA

2017

O direito a uma boa administração pública é um dos direitos fundamentais da pessoa, garantido pelo artigo 41 da Carta dos direitos fundamentais da União Europeia, que, em 2009, por força do Tratado de Lisboa, tornou-se juridicamente vinculante com o mesmo valor de fonte primária dos Tratados europeus. Ele é definido como o direito de cada pessoa (física e jurídica) de receber, por parte da autoridade pública, em relação às questões que se lhe refiram, um tratamento imparcial, equitativo e num prazo razoável. Inclui, também, os seguintes direitos de natureza procedimental: a ser ouvida, antes de, a seu respeito, ser tomada qualquer medida individual que a afete desfavoravelmente; a ter acess…