Search results for "SOD"
showing 10 items of 2830 documents
Effects of Long-Term Nitroglycerin Treatment on Endothelial Nitric Oxide Synthase (NOS III) Gene Expression, NOS III–Mediated Superoxide Production, …
2000
Abstract —Long-term nitroglycerin (NTG) treatment has been shown to be associated with cross-tolerance to endothelium-dependent vasodilators. It may involve increased production of reactive oxygen species (such as superoxide, O 2 ·− ) that rapidly inactivate the nitric oxide (NO) released from the endothelial cells. It remains to be elucidated, however, whether long-term treatment with NTG alters the activity and expression of the endothelial NO synthase (NOS III) and whether this enzyme can contribute to O 2 ·− formation. We studied the influence of long-term NTG treatment on the expression of NOS III as assessed by RNase protection assay and Western blot. Tolerance was measured ex vivo i…
Noziedzīgi iegūtu līdzekļu legalizēšana- pastāvošās problēmas, iespējamie risinājumi
2019
Noziedzīgi iegūtu līdzekļu legalizēšana ir noziegums, kas paredzēts Krimināllikuma 195.pantā, papildus tam, šī nozieguma apkarošanai ir ticis pieņemts arī atsevišķs likums, tieši Noziedzīgi iegūtu līdzekļu legalizēšanas un terorisma finansēšanas novēršanas likums. Neskatoties uz to, ka šo vienu noziegumu regulē ļoti plašs un izvērsts regulējums, tā apkarošana gan Latvijā, gan pasaulē ir bijusi ļoti neefektīva visā tā pastāvēšanas laikā. Tieši tāpēc šī Bakalaura darba mērķis ir noteikt problēmas kādas pastāv atklājot, izmeklējot un notiesājot personas noziedzīgi iegūtu līdzekļu legalizēšanas gadījumos, lai pēc tam varētu piedāvāt konkrētus risinājumus šo problēmu turpmākai novēršanai. Lai sa…
Prosodic phenomena in simultaneous interpreting
2005
This paper reports on an empirical study on prosody in English-German simultaneous interpreting. It discusses prosody with particular reference to its tonal, durational and dynamic features, such as intonation, pauses, rhythm and accent, as well as its main functions, i.e. structure and prominence. Following a review of previous studies on the topic, a conceptual approach for the analysis of prosody in terms of structure and prominence is developed and subsequently applied to an authentic corpus of professional simultaneous interpretation consisting of three German versions of a 72-minute English source text. Prosodic patterns in the corpus are analyzed by means of a computer-aided method u…
Salt and Aroma Compound Distributions Influence Flavour Release and Temporal Perception While Eating Hot-Served Flans.
2021
International audience; To counteract the negative effect of salt overconsumption on health, strategies have been developed to reduce the salt content in food products. Among them, two promising strategies based on odour-induced saltiness enhancement and the heterogeneous distribution of flavour compounds were combined and assessed in four-layer cream-based snacks. To investigate the relationship between saltiness enhancement, temporal release and perception of flavour compounds in hot snacks with heterogeneous distribution of salt and aroma compounds, complementary techniques were used: nose space PTR-Tof-MS (Proton Transfer Reaction-Time of Flight–Mass Spectrometry) to assess the release …
Sodium ions in model cheeses at molecular and macroscopic levels
2011
Chapitre suite à une communication à la '10th International Conference on the Application of Magnetic Resonance in Food Science' à Clermont-Ferrand (France), 13-15 septembre 2010.; International audience; The excessive consumption of sodium is one of the causes of nutritional related-health problems. The reduction of salt content without affecting technological and sensorial properties of foodstuffs is currently a challenge for the food industry1. There is a need to develop tools to quantify the “active” sodium ions in food products at molecular and macroscopic levels to better understand the in-mouth salt release. . . In this context, methods for the quantification of the bound fraction of…
Structural and dynamical properties of sodium silicate melts: An investigation by molecular dynamics computer simulation
2001
We present the results of large scale computer simulations in which we investigate the static and dynamic properties of sodium disilicate and sodium trisilicate melts. We study in detail the static properties of these systems, namely the coordination numbers, the temperature dependence of the Q^(n) species and the static structure factor, and compare them with experiments. We show that the structure is described by a partially destroyed tetrahedral SiO_4 network and the homogeneously distributed sodium atoms which are surrounded on average by 16 silicon and other sodium atoms as nearest neighbors. We compare the diffusion of the ions in the sodium silicate systems with that in pure silica a…
PPARγ as an indicator of vascular function in an experimental model of metabolic syndrome in rabbits
2021
Abstract Background and aims Underlying mechanisms associated with vascular dysfunction in metabolic syndrome (MetS) remain unclear and can even vary from one vascular bed to another. Methods In this study, MetS was induced by a high-fat, high-sucrose diet, and after 28 weeks, aorta and renal arteries were removed and used for isometric recording of tension in organ baths, protein expression by Western blot, and histological analysis to assess the presence of atherosclerosis. Results MetS induced a mild hypertension, pre-diabetes, central obesity and dyslipidaemia. Our results indicated that MetS did not change the contractile response in either the aorta or renal artery. Conversely, vasodi…
Tight Link Between Our Sense of Limb Ownership and Self-Awareness of Actions
2007
Background and Purpose— Hemiparetic stroke patients with disturbed awareness for their motor weakness (anosognosia for hemiparesis/-plegia [AHP]) may exhibit further abnormal attitudes toward or perceptions of the affected limb(s). The present study investigated the clinical relationship and the anatomy of such abnormal attitudes and AHP. Methods— In a new series of 79 consecutively admitted acute stroke patients with right brain damage and hemiparesis/ -plegia, different types of abnormal attitudes toward the hemiparetic/plegic limb (asomatognosia, somatoparaphrenia, anosodiaphoria, misoplegia, personification, kinaesthetic hallucinations, supernumerary phantom limb) were investigated. Re…
Effect of the several epoxy resin-based sealer compositions on adhesion interface in radicular dentin after calcium hydroxide intracanal medication r…
2021
Made available in DSpace on 2022-04-29T08:32:43Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-09-01 Background: This study evaluated the effects of several epoxy resin-based sealer compositions (AHP, AH Plus; ADS, Adseal; SPL, Sealer Plus) on bond strength and intratubular dentin penetration of the endodontic obturation, in root canal previously treated with calcium hydroxide intracanal medication (CH) and removed by continuous ultrasonic irrigation (CUI). Material and Methods: Forty-five maxillary canines were prepared up to F5 (ProTaper system), filled with CH, coronally sealed, and stored at 37ºC. After 1 week, CH was removed using 2.5% sodium hypochlorite energized by CUI. The …
EFFECTS OF PHORBOL 12,13-DIACETATE AND ITS INFLUENCE ON SPASMOGENIC RESPONSES IN NORMAL AND SENSITIZED GUINEA-PIG TRACHEA
1995
Abstract We have studied the effects of phorbol 12,13-diacetate (PDA) and its influence on a variety of spasmogenic responses in trachea isolated in from normal and sensitized guinea-pigs. Tracheal preparations were denuded of epithelium, treated with indomethacin (2·8 μm), and cooled to 20°C. In these experimental conditions, tracheal strips contracted to PDA (0·1 nm-1 μm). Contractions to PDA (1 μm) were greater in sensitized tissues. In normal trachea, contractions to PDA (0·1 μm) were depressed by H-7, 1-(5-isoquinolinyl-sulphonyl)-2-methylpiperazine, (50 μm), amiloride (10 μm), verapamil (10 μm) and Ca2+-free exposure. Similar effects were obtained in sensitized trachea except that PDA…