Search results for "SPECT"

showing 10 items of 28650 documents

Profiling Dopamine-Induced Oxidized Proteoforms of β-synuclein by Top-Down Mass Spectrometry

2021

The formation of multiple proteoforms by post-translational modifications (PTMs) enables a single protein to acquire distinct functional roles in its biological context. Oxidation of methionine residues (Met) is a common PTM, involved in physiological (e.g., signaling) and pathological (e.g., oxidative stress) states. This PTM typically maps at multiple protein sites, generating a heterogeneous population of proteoforms with specific biophysical and biochemical properties. The identification and quantitation of the variety of oxidized proteoforms originated under a given condition is required to assess the exact molecular nature of the species responsible for the process under investigation…

β synucleinPhysiologyClinical BiochemistryContext (language use)RM1-950Mass spectrometryProtein oxidationBiochemistryArticlechemistry.chemical_compoundDopamine oxidationDopamineSettore BIO/10 - BiochimicamedicineTop-down mass spectrometryFragmentation (cell biology)Proteoforms relative quantitationMolecular BiologyHuman β-synucleinMethionineMethionine sulfoxideCell BiologychemistryBiochemistryTherapeutics. PharmacologyMethionine sulfoxidemedicine.drug
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Conformational investigation of alpha,beta-dehydropeptides. IX. N-Acetyl-(E)-alpha,beta-methylamide: stereoelectronic properties from infrared and th…

1998

The Fourier transform infrared spectra of Ac-(E)-deltaAbu-NHMe were analyzed to determine the predominant solution conformation(s) of this (E)-alpha,beta-dehydropeptide-related compound and the electron density perturbation in its amide groups. The measurements were performed in dichloromethane and acetonitrile in the region of mode vs (N-H), amide I, amide II and vs (C(alpha)=Cbeta). The equilibrium geometrical parameters, calculated by a method based on the density functional theory with the B3LYP functional and the 6-31G* basis set, were used to support spectroscopic interpretation and gain some deeper insight into the molecule. The experimental and theoretical data were compared with th…

β-dehydroamino acidsFTIR spectroscopyα(E)-αMolecular orbital methodAmidic resonanceC5 hydrogen bondβ- dehydrobutyrineC5 conformationSolution peptide conformationDensity functionalsJOURNAL OF PEPTIDE RESEARCH
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Characterization and antimicrobial activity of the volatile components of the flowers of Magydaris tomentosa (Desf.) DC. collected in Sicily and Alge…

2014

The essential oils of the flowers of Magydaris tomentosa (Desf.) DC. (Apiaceae) collected in Sicily (MSi) and Algeria (MAl), respectively, were obtained by hydrodistillation, and their compositions were analysed. The analyses allowed the identification and quantification of 23 components in MSi and 60 compounds in MAl, respectively, showing a very different profile in the composition of the two populations. The main components of MSi were cembrene (28.2%), α-springene (17.5%) and β-springene (14.8%), also present in MAl but in lesser amount (0.4%, 1.8% and 0.9%, respectively), whereas the principal constituents of MAl were (E)-nerolidol (35.4%), α-costol (13.3%) and β-costol (6.8%). Both MS…

β-springeneFlowersMicrobial Sensitivity TestsPlant ScienceBiochemistryMagydaris tomentosaGas Chromatography-Mass Spectrometryessential oilAnalytical ChemistryAnti-Infective Agentsα\-springeneStaphylococcus epidermidisparasitic diseasesOils VolatileMagydarisSicilyApiaceaeantimicrobial activitybiologyTraditional medicineOrganic ChemistrySettore CHIM/06 - Chimica Organicabiology.organism_classificationAntimicrobialαspringeneAnti-Bacterial AgentsPlant LeavesChemotaxonomyAlgerialipids (amino acids peptides and proteins)Composition (visual arts)DiterpenesAntibacterial activitySesquiterpenesApiaceae
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The Use of Stable Isotope Ratio Analysis to Trace European Sea Bass (D. labrax) Originating from Different Farming Systems

2020

This study aimed to determine whether isotopic ratio mass spectrometry (IRMS) can discriminate farmed European sea bass according to different farming systems and geographic origins. Dicentrarchus labrax of commercial size from three different rearing systems (concrete tank inland, sea cages, and extensive methods in valleys or salt works) were collected at the trading period (autumn&ndash

δ18Ostable isotopesgeographic origin01 natural sciencesArticle0404 agricultural biotechnologyAquacultureSettore AGR/20 - Zoocolturelcsh:ZoologyDicentrarchus labrax<i>Dicentrarchus labrax</i>lcsh:QL1-991Settore BIO/06 - Anatomia Comparata E CitologiaSea bassIsotope-ratio mass spectrometryaquaculture; Dicentrarchus labrax; stable isotopes; traceability; farming system; geographic origin; IRMS; sea bass; fish; authenticationfishaquaculture Dicentrarchus labrax stable isotopes traceability farming system geographic origin IRMS sea bass fish authenticationlcsh:Veterinary medicineGeneral Veterinaryδ13CbiologyStable isotope ratiobusiness.industry010401 analytical chemistry04 agricultural and veterinary sciencesδ15NIRMSbiology.organism_classification040401 food science0104 chemical sciencesFisherytraceabilityaquaculturelcsh:SF600-1100authenticationEnvironmental sciencefarming systemAnimal Science and ZoologyDicentrarchusbusinesssea bassAnimals
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Высокочастотные безэлектродные источники света

1992

Высокочастотные безэлектродные лампы:NATURAL SCIENCES::Physics::Other physics::Optics [Research Subject Categories]Elektriskās spuldzesИсточники светаOptikaSpektroskopijaОптические приборыОптикаElectric lampsСпектроскопияСпектральный анализSpectroscopy
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Book reviews: P. Cheyne, A. Hamilton, M. Paddison (eds.). Philosophy of Rhythm: Aesthetics, Music, Poetics. New York: Oxford University Press, 2019

2021

Гамильтон ЭндиПаддисон МаксMusic-Psychological aspectsMusikCheyne P .Musical meter and rhythmPhilosophieЧейн ПитерPaddison M.Hamilton A.Rhythmus:HUMANITIES and RELIGION::Aesthetic subjects::Music [Research Subject Categories]MusicMusical perception
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Valoda: nozīme un forma. 4: Kategoriju robežas gramatikā

2014

Rakstu krājums "Valoda: nozīme un forma. 4. Kategoriju robežas gramatikā" ir LU 71. konferences Humanitāro zinātņu fakultātes Latviešu un vispārīgās valodniecības katedras 27.02.2013. rīkotās sekcijas referātu apkopojums.

ТenoteiksmeMorphologyPārejamība jeb transitivitāteAristoteļis "Runas māksla"SintakseIgauņu valodaVārddarināšanas kalkiLatviskojumsKomponentu analīzes metodeDeklinācijaValence:HUMANITIES and RELIGION::Languages and linguistics [Research Subject Categories]Palīgdarbības vārdsDarbības vārda veidsVārddarināšanaDesemantizēšanāsLatvian aspect
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Underground investigation of extensive air showers spectra at high energy range of cosmic rays and other research in the Pyhäsalmi mine

2020

Abstract High energy particles reaching the Earth’s atmosphere are known as cosmic rays. As a result of interactions with nuclei of air molecules, cosmic rays induce showers of secondary particles, which can be divided into 3 components: electromagnetic, hadronic and muonic components. The Experiment with Multi Muon Array (EMMA), located at the depth of 75 m in the Pyhäsalmi mine in Finland, investigates the muonic component of the Extensive Air Showers (EAS) to deduce the direction, energy, and the mass of the primary cosmic ray particles. In this paper we give a concise description and methodology used by EMMA followed by a brief review of the C14 experiment. Finally, we review the feasib…

ғарыш сәулелеріPhysics::Instrumentation and DetectorsastrofysiikkaAstrophysics::High Energy Astrophysical PhenomenaBoreholekneeOcean EngineeringCosmic rayhiukkasfysiikkaSpectral lineAtmosphereNuclear physicsnuclear and elementary particle physicscosmic rayshigh-energy muonжоғары энергиялы мюонPhysicsтізе аймағыtheoretical physicsRange (particle radiation)Muonastrophysicsкең ауқымды нөсер (КАН)Neutrino detectorilmaisimetExtensive Air Shower (EAS)EMMANeutrinokosminen säteily
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Translation ‘going social’? Challenges to the (Ivory) Tower of Babel

2010

The discussion of “turns” or “paradigmatic shifts” which we can witness in the last few years in Translation Studies undoubtedly testifies to the discipline’s increasing establishment and recognition within the scientific community and of the increasing practice of a transdisciplinary research. These shifts also include what has been called the “sociological turn”, which comprises the cluster of questions dealing not only with the networks of agents and agencies and the interplay of their power relations, but also the social discursive practices which mould the translation process and which decisively affect the strategies of a text to be translated. This paper seeks to foreground some of t…

“Sociological turn”EthicsLinguistics and LanguageUNESCO::CIENCIAS DE LAS ARTES Y LAS LETRASTraducció -- Aspectes socialsSocial perspectiveProcess (engineering)Traducción e InterpretaciónMethodologyPower relationsSociological turnWitnessLanguage and LinguisticsEducationEpistemologyTranslation sociology; Sociological turn; Methodology; Ethics; Translation and activism:CIENCIAS DE LAS ARTES Y LAS LETRAS [UNESCO]Translation studiesTranslation sociologyIvory towerSociologyAffect (linguistics)Social scienceTranslation and activism
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Management of Patients with Gastric or Gastroesophageal Junction Cancer: From Theory to Integrated Clinical Path- ways Implementation in the Real Wor…

2022

Introduction: Best care of esophagogastric junction and gastric cancer (EGC) requires a complex, timely interaction between members of a multi-disciplinary team (MDT). An integrated clinical pathway (ICP) is necessary to achieve this goal as well as the implementation of its use in daily practice. The objective of this study was to elaborate on an integrated clinical pathway for the multi-disciplinary management of ECG. Authors also put in act an implementation program to improve adherence to guidelines thought an ICP. Method: This prospective work carried out by a multi-institutional MDT in Italy identified expert panel extracted relevant recommendations and/or statements from published pa…

flowchart.Italyesophagogastric junction cancerStomach Neoplasmsgastric cancerCritical PathwaysHumansclinical pathwayEsophagogastric JunctionProspective Studiesmultidisciplinary team
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