Search results for "STED"

Analysis of the variability of Drosophila azteca and D. athabasca populations revealed by randomly amplified polymorphic DNA

2009

The disribution ranges of Drosophila azteca and D. athabasca overlap in northen California and southern Oregon. Seven populations, four of which are located in this area, were studied. Large random amplified polymorphic DNA (RAPD) variation was found within species; nevertheless, more than half the primers used in the study yielded greater diofference between than within species. A nested analysis of molecular variance (AMOVA) showed that the variance between populations within species was significantly greater than zero for 55% of the oligonucleotides used, which provided evidence for an underlying geographical structure of these populations. Specimens of D. azteca and D. athabasca from Sa…

Estimation of Purkinje trees from electro-anatomical mapping of the left ventricle using minimal cost geodesics

2015

The electrical activation of the heart is a complex physiological process that is essential for the understanding of several cardiac dysfunctions, such as ventricular tachycardia (VT). Nowadays, patient-specific activation times on ventricular chambers can be estimated from electro-anatomical maps, providing crucial information to clinicians for guiding cardiac radio-frequency ablation treatment. However, some relevant electrical pathways such as those of the Purkinje system are very difficult to interpret from these maps due to sparsity of data and the limited spatial resolution of the system. We present here a novel method to estimate these fast electrical pathways from the local activati…

German Marathon Runners' Opinions on and Willingness to Pay for Environmental Sustainability

2021

Research on sustainability and/in sport and, specifically, on the ecological aspects of participatory sporting events is still very scarce despite the recognition these topics have received by actors like, for instance, the European Commission and the United Nations. Against this backdrop, this paper sheds light on a field that is virtually uncharted in academic research, which is the environmental attitudes and willingness to pay for environmental sustainability of participants in participatory sporting events in Europe. In collaboration with the organizer of the Frankfurt Marathon, a study was conducted with a specific focus on German (speaking) marathon runners. In total 1764 data sets w…

An Analysis and Comparison of Expectations and Perceptions on Sustainable Tourism among Italian and German Tourists

2016

The paper investigates the relationship of Italian and German consumers with sustainable tourism through a quantitative online questionnaire. The study’s first aim is to understand the representation of sustainable tourism. It also analyzes if the issue of sustainability denotes an abstract or concrete value to consumers, the extent to which sustainability is considered an important factor in the process of purchasing and consumption of a tourism product, and then becomes a driver for consumers to choose from. The analysis of tourist flows and the literature of the field have shown that in Germany there is extensive experience on the topics of sustainability and sustainable tourism, while l…

Impact of COVID-19 Confinement on Physical Activity and Sedentary Behaviour in Spanish University Students: Role of Gender

2021

During the COVID-19 pandemic, entire populations were instructed to live in home-confinement to prevent the expansion of the disease. Spain was one of the countries with the strictest conditions, as outdoor physical activity was banned for nearly two months. This study aimed to analyse the changes in physical activity and sedentary behaviours in Spanish university students before and during the confinement by COVID-19 with special focus on gender. We also analysed enjoyment, the tools used and motivation and impediments for doing physical activity. An online questionnaire, which included the International Physical Activity Questionnaire Short Form and certain &ldquo

Sociodemographic factors as determinants of quality of life and quality of social interactions among heterosexual couples undergoing assisted reprodu…

2021

Introduction When facing with stressful physical and psychosocial events, sociodemographic factors can be an important factor for quality of life and quality of social interactions [1]. The experience of infertile couples undergoing ART is a complex and stressful process that may have a negative effect on quality of life [2]. There is a need to better understand how certain sociodemographic factors impact on the quality of life and in the quality of social interactions of patients undergoing ART, in order to be able to anticipate the consequences from an integrated care perspective.MethodsThis study aims to assess the relationship between sociodemographic factors (sex, marital status and em…

Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countr…

2015

Summary Background The Global Burden of Disease Study 2013 (GBD 2013) aims to bring together all available epidemiological data using a coherent measurement framework, standardised estimation methods, and transparent data sources to enable comparisons of health loss over time and across causes, age–sex groups, and countries. The GBD can be used to generate summary measures such as disability-adjusted life-years (DALYs) and healthy life expectancy (HALE) that make possible comparative assessments of broad epidemiological patterns across countries and time. These summary measures can also be used to quantify the component of variation in epidemiology that is related to sociodemographic develo…

2016

Summary Background Healthy life expectancy (HALE) and disability-adjusted life-years (DALYs) provide summary measures of health across geographies and time that can inform assessments of epidemiological patterns and health system performance, help to prioritise investments in research and development, and monitor progress toward the Sustainable Development Goals (SDGs). We aimed to provide updated HALE and DALYs for geographies worldwide and evaluate how disease burden changes with development. Methods We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015) for all-cause mortality, cause-specific mortality, and non-fatal disease burden to derive …

Impact on physical fitness of exercise promotion service utilizing social media

2014

Summary Study aim: the purpose of the present study was to survey the impact of a social media platform on physical fitness, physical activity levels and daily sitting time. Material and methods: a total of 2039 users (1445 women and 594 men) of the social media service (HeiaHeia, Helsinki, Finland) voluntarily participated in the study by answering an online questionnaire provided by a survey. Results: about 63.8% of the participants reported that the service has advanced their perceived level of physical fitness, while 36.2% reported no impact on their fitness. Most participants (71.3%) with BMI over 25 reported that the service had helped them to improve their physical fitness. Participa…

(R)-NODAGA-PSMA: A Versatile Precursor for Radiometal Labeling and Nuclear Imaging of PSMA-Positive Tumors

2015

Purpose The present study aims at developing and evaluating an urea-based prostate specific membrane antigen (PSMA) inhibitor suitable for labeling with 111In for SPECT and intraoperative applications as well as 68Ga and 64Cu for PET imaging. Methods The PSMA-based inhibitor-lysine-urea-glutamate-coupled to the spacer Phe-Phe-D-Lys(suberoyl) and functionalized with the enantiomerically pure prochelator (R)-1-(1-carboxy-3-carbotertbutoxypropyl)-4,7-carbotartbutoxymethyl)-1,4,7-triazacyclononane ((R)-NODAGA(tBu)3), to obtain (R)-NODAGA-Phe-Phe-D-Lys(suberoyl)-Lys-urea-Glu (CC34). CC34 was labeled with 111In, 68Ga and 64Cu. The radioconjugates were further evaluated in vitro and in vivo in LNC…