Search results for "STELLA"
showing 10 items of 1995 documents
Complement components C1q, C1r/C1s, and C1inh in rheumatoid arthritis
1995
Objective. To analyze the synovial site and the cell types expressing C1q, C1r/C1s, and C1–esterase inhibitor (C1INH) and to characterize newly synthesized C1q in patients with rheumatoid arthritis (RA). Methods. Tissue and primary cell cultures of synovium from RA patients were analyzed for C1q, C1r/C1s, and C1INH by Northern blotting, in situ hybridization, and pulse-chase experiments for C1q. Results. The de novo synthesis of C1q, C1r/C1s, and C1INH in synovium and primary cell cultures was proven by Northern blot and by antigenic and functional analysis. In in situ hybridization experiments, the synovial lining cell layer was identified as the site of C1q, C1r, and C1INH expression. In …
Changes in carnitine octanoyltransferase activity induce alteration in fatty acid metabolism
2011
The peroxisomal beta oxidation of very long chain fatty acids (VLCFA) leads to the formation of medium chain acyl-CoAs such as octanoyl-CoA. Today, it seems clear that the exit of shortened fatty acids produced by the peroxisomal beta oxidation requires their conversion into acyl-carnitine and the presence of the carnitine octanoyltransferase (CROT). Here, we describe the consequences of an overexpression and a knock down of the CROT gene in terms of mitochondrial and peroxisomal fatty acids metabolism in a model of hepatic cells. Our experiments showed that an increase in CROT activity induced a decrease in MCFA and VLCFA levels in the cell. These changes are accompanied by an increase in …
Evidence for a common progenitor of epithelial and mesenchymal components of the liver
2013
Tissues of the adult organism maintain the homeostasis and respond to injury by means of progenitor/stem cell compartments capable to give rise to appropriate progeny. In organs composed by histotypes of different embryological origins (e.g. The liver), the tissue turnover may in theory involve different stem/precursor cells able to respond coordinately to physiological or pathological stimuli. In the liver, a progenitor cell compartment, giving rise to hepatocytes and cholangiocytes, can be activated by chronic injury inhibiting hepatocyte proliferation. The precursor compartment guaranteeing turnover of hepatic stellate cells (HSCs) (perisinusoidal cells implicated with the origin of the …
Determination of usnic and perlatolic acids and identification of olivetoric acids in Northern reindeer lichen (Cladonia stellaris) extracts
2010
AbstractThe ecologically important lichen Cladonia stellaris forms thick carpets in boreal forest floors. In addition to affecting temperature and water conditions in the soil underneath, the secondary metabolites formed by the lichen layer are of ecological interest. In this paper, we investigated the distribution of lichen acids in C. stellaris collected at different latitudes in Finland and developed methods to quantify the two optical enantiomers of usnic acid separately. The lichen extracts were analysed by high-performance liquid chromatography (HPLC) with UV and mass spectrometric (MS) detection and by gas chromatography with flame ionization (GC-FID) and MS detection. Usnic acid and…
Probing the electronic state of a single coronene molecule by the emission from proximate fluorophores.
2012
We measured electronic transitions of the 2D graphene-type molecule hexa-peri-hexabenzocoronene (HBC) at the single-molecule level. The large intersystem crossing rate and long triplet state lifetime in the range of seconds are prohibitive for direct single-molecule observation. By covalently coupling fluorescent acceptor molecules (perylenecarboximide, PMI) to HBC, efficient singlet energy transfer gives rise to strong PMI fluorescence. Confocal single-molecule fluorescence microscopy with two excitation colours matching the HBC and PMI transition frequencies, respectively, was conducted. Single HBC-6PMI molecules were readily observed via the PMI emission. It was found that after selectiv…
Detailed study of SNR G306.3–0.9 using XMM-Newton and Chandra observations
2016
Aims. We aim to study the spatial distribution of the physical and chemical properties of the X-ray emitting plasma of the supernova remnant (SNR) G306.3-0.9 in detail to obtain constraints on its ionization stage, the progenitor supernova explosion, and the age of the remnant. Methods. We used combined data from XMM-Newton and Chandra observatories to study the X-ray morphology of G306.3-0.9 in detail. A spatially resolved spectral analysis was used to obtain physical and geometrical parameters of different regions of the remnant. Spitzer infrared observations, available in the archive, were also used to constrain the progenitor supernova and study the environment in which the remnant evol…
Sylua de vocablos de scriuir con algunas reglas de Orthographia
1569
Sig. [ ]2, A-I8, K2; A-H8 Els grav. xil. a les port. d'alguns abecedaris. - Escuts heràldics del arquebisbe Joan de Ribera a les port. de cada part. - Algunes capitals grav. Son 2 parts en 1 vol., amb un total de 8 abecedaris específics. - La "Segunda Parte del Vocabulario del Humanista..." amb port. i pag. pròpia, inclou "Sylua de vocablos de scriuir con algunas reglas de Orthographia". - Text amb postil·les marginals. - Reclams. - Errates de pag.
Carta exortatoria, en que el Obispo de Segovia pone delante de los ojos de todos sus Eclesiasticos un espejo, en que registren la Dignidad que gozan,…
1743
Sig. A-K4 Signat al final "Diego, Obispo de Segovia". - Es Diego García de Medrano Port. orlada. - Text amb notes marginals. - Reclams. - Capital grav. i vinyeta amb l'anagrama de jesucrist al començament del text
Determination of queuosine derivatives by reverse-phase liquid chromatography for the hypomodification study of Q-bearing tRNAs from various mammal l…
2004
Three queuosine derivatives (Q-derivatives) have been found at position 34 of four mammalian so-called Q-tRNAs: queuosine (Q) in tRNA(Asn) and tRNA(His), mannosyl-queuosine (manQ) in tRNA(Asp), and galactosyl-queuosine (galQ) in tRNA(Tyr). An analytical procedure based on the combined means of purified tRNA isolation from liver cells and ribonucleoside analysis by reverse-phase high performance liquid chromatography coupled with real-time UV-spectrometry (RPLC-UV) was developed for the quantitative analysis of the three Q-derivatives present in total tRNA from liver tissues and liver cell cultures. Using this analytical procedure, the rates of Q-tRNA modification were studied in total tRNAs…
Historia del Colegio Viejo de S. Bartholomé Mayor de la celebre Universidad de Salamanca : segunda parte, tomo primero : que contiene las vidas de l…
1768
Índex És continuació de : "Historia del Colegio Viejo de S. Bartholomé Mayor de la celebre Universidad de Salamanca : vida del ... Sr. Don Diego de Anaya Maldonado ... : primera parte / escrita por ... Francisco Ruiz de Vergara y Alava ..." Grav. calc. de port. representa al Col·legi Els f. de grav. calc., representen a Carles III i al arquebisbe de Sevilla Diego de Anaya Les il. són els grav. calc. de capçalera, representen als fundadors Sign.: *-***4, A-Qqqqqq4, Rrrrrr5 Port. amb grav. calc. en la capçalera Lletres inicials adornades, frisos tip. decoratius i capçaleres calc. Part del text a dues col. Notes a peu de pàg. i reclams