Search results for "STING"
showing 10 items of 3756 documents
AGuIX® from bench to bedside-Transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine.
2019
International audience; AGuIX® are sub-5 nm nanoparticles made of a polysiloxane matrix and gadolinium chelates. This nanoparticle has been recently accepted in clinical trials in association with radiotherapy. This review will summarize the principal preclinical results that have led to first in man administration. No evidence of toxicity has been observed during regulatory toxicity tests on two animal species (rodents and monkeys). Biodistributions on different animal models have shown passive uptake in tumours due to enhanced permeability and retention effect combined with renal elimination of the nanoparticles after intravenous administration. High radiosensitizing effect has been obser…
Automatic Generation of Land Surface Emissivity Maps
2011
The remote sensing measurement of the land surface temperature (LST) from satellites provides an overview of this magnitude on a continuous and regular basis. The study of its evolution in time and space is a critical factor in many scientific fields such as weather forecasting, detection of forest fires, climate change, etc. The main problem of making this measurement from satellite data is the need to correct the effects of the atmosphere and the land surface emissivity (LSE). Nowadays, these corrections are usually made using a split-window algorithm, which has an explicit dependence on land surface emissivity. Therefore, the aim of our work was to define an enhanced vegetation cover met…
The green roofs for reduction in the load on rainwater drainage in highly urbanised areas
2021
AbstractRapid weather phenomena, particularly sudden and intense rainfall, have become a problem in urban areas in recent years. During heavy rainfall, urban rainwater drainage systems are unable to discharge huge amounts of runoff into collecting reservoirs, which usually results in local flooding. This paper presents attempts to forecast a reduction in the load on the rainwater drainage system through the implementation of green roofs in a case study covering two selected districts of Opole (Poland)—the Old Town and the City Centre. Model tests of extensive and intensive roofs were carried out, in order to determine the reduction of rainwater runoff from the roof surface for the site unde…
Forecasts on the development of hydrogen refuelling infrastructures in Portugal
2021
In Portugal, the transition to new forms of mobility has begun in recent years, but there are still obstacles to overcome. Currently, hybrid vehicles (PHEVs) are the most widespread and accepted by the community and that is probably due to range anxiety, having in fact the possibility of double charging (both through the thermal engine and the electric battery). Furthermore, it must be considered that in addition to electric vehicles, another valid alternative to mobility in the near future is the hydrogen vehicles one. These appear to be even more sustainable from the point of view of air emissions, but on the other hand the costs for the production of hydrogen are still too high. Then, th…
Pooling of Nasopharyngeal Swab Specimens for SARS-CoV-2 detection by RT-PCR
2020
ABSTRACTSystematic testing of large population groups by RT-PCR is mandatory to Covid-19 case identification and contact tracing in order to minimize the likelyhood of resurgence in contagion. Sample pooling for RT-PCR has been effectively used to detect community transmission of SARS CoV-2. Nevertheless, this procedure may decrease the sensitivity of RT-PCR assays due to specimen dilution. We evaluated the efficacy of this strategy for diagnosis of Covid-19 using a sensitive commercially-available RT-PCR targeting SARS CoV-2 E and RdRp genes in a single reaction. A total of 20 mini-pools containing either 5 (n=10) or 10 (n=10) nasopharyngeal exudates collected in universal transport medium…
Are validation scales useful for Detecting Deliberately Faked Personality Tests? A study in incarcerated populations
2012
Personality self-report questionnaires are frequently used in forensic settings to detect psychopathology, to predict recidivism, and to assess adaptability to life in prison. Although most personality questionnaires include validity or control scales, even with the scales most outcomes can be easily manipulated. The aim of this study is to analyze the utility of the control scales of the Situational Personality Questionnaire. A sample of 200 male prisoners was randomized into two groups. Both groups completed the SPQ as a part of the mandatory psychological assessment when they entered prison, and then again 8 months later. In time 2, one group received instructions to falsify the results …
Atgriezeniskā skaņas kanāla un ieraksta režīma testu automatizācija Axia Fusion pultīm
2017
Kvalifikācijas darbs ir izstrādāts, lai pārbaudītu vienas no "Telos Alliance" produkta, Axia Fusion Consoles, pielāgotajām un noklusētajām atpakaļejošajām opcijām un ieraksta režīmu opcijām. Pārbaudes process ietver atbilstošu konfigurāciju un iestatījumu iestatīšanu katram testa scenārijam un audio līmeņu pārbaudei vai vērtību iegūšanai, lai noskaidrotu, vai rezultāts atbilst sagaidāmam guvumam. Backfeed Test ir sadalīts divos dažādos moduļos: Default Backfeed tests un Custom Backfeed tests. Katrs modulis tiek tālāk iedalīts trīs dažādos moduļos; Konfigurācija, funkcionālie un testēšanas moduļi, kas atbilst to funkcijām un neatkarībai, kā arī galvenais modulis, kas organizē visus pārējos m…
Innovative systems based on optical nanoantennas for energy harvesting application
The purpose of this study is to outline the main guidelines for the design of arrays of optical rectennas aiming to harvest energy and for the optimization of the power transfer to an external load. In particular, the novelty of this study consists in introducing the concept of the integrated design between the array of optical rectennas and the harvesting circuit able to exploit the available energy. The design of the array represents the crucial point in order to optimize the power transfer between the antenna and the load and can influence the rectenna design. On the other hand, the maximum power transfer to the load has to be obtained under matching conditions between the array and the …
Comparing Recurrent Neural Networks using Principal Component Analysis for Electrical Load Predictions
2021
Electrical demand forecasting is essential for power generation capacity planning and integrating environment-friendly energy sources. In addition, load predictions will help in developing demand-side management in coordination with renewable power generation. Meteorological conditions influence urban area load pattern; therefore, it is vital to include weather parameters for load predictions. Machine Learning algorithms can effectively be used for electrical load predictions considering impact of external parameters. This paper explores and compares the basic Recurrent Neural Networks (RNN); Simple Recurrent Neural Networks (Vanilla RNN), Gated Recurrent Units (GRU), and Long Short-Term Me…