Search results for "STM"

Genetic and Epigenetic Factors of Takotsubo Syndrome: A Systematic Review

2021

Takotsubo syndrome (TTS), recognized as stress’s cardiomyopathy, or as left ventricular apical balloon syndrome in recent years, is a rare pathology, described for the first time by Japanese researchers in 1990. TTS is characterized by an interindividual heterogeneity in onset and progression, and by strong predominance in postmenopausal women. The clear causes of these TTS features are uncertain, given the limited understanding of this intriguing syndrome until now. However, the increasing frequency of TTS cases in recent years, and particularly correlated to the SARS-CoV-2 pandemic, leads us to the imperative necessity both of a complete knowledge of TTS pathophysiology for identifying bi…

Employment trajectories until midlife associate with early social role investments and current work-related well-being

2021

Applying social investment theory (SIT), we examined whether employment trajectories until midlife, with differential investments in education and employment, are associated with social investments during early life and with work-related well-being in midlife, with a special reference to potential differences between self-employment and paid work. In the Northern Finland Birth Cohort 1966 (n = 6496; 2963 men, 3533 women), life-history calendars from age 16 to 45 were used to determine the respondents’ yearly employment statuses (student, full-time employee, part-time employee, self-employed, unemployed, on parental leave, on sabbatical leave or otherwise not working). Latent class analysis …

A Universal Length-Dependent Vibrational Mode in Graphene Nanoribbons

2019

Graphene nanoribbons (GNRs) have attracted considerable interest as their atomically tunable structure makes them promising candidates for future electronic devices. However, obtaining detailed information about the length of GNRs has been challenging and typically relies on low-temperature scanning tunneling microscopy. Such methods are ill-suited for practical device application and characterization. In contrast, Raman spectroscopy is a sensitive method for the characterization of GNRs, in particular for investigating their width and structure. Here, we report on a length-dependent, Raman active low-energy vibrational mode that is present in atomically precise, bottom-up synthesized armch…

Formulations and exact algorithms for the distance-constrained generalized directed rural postman problem

2017

[EN] The generalized directed rural postman problem is an arc routing problem with many interesting real-life applications, such as routing for meter reading. In this application, a vehicle with a receiver travels through a series of neighborhoods. If the vehicle gets closer than a certain distance to a meter, the receiver is able to record the gas, water, or electricity consumption. Therefore, the vehicle does not need to traverse every street, but only a few, to get close enough to each meter. We study an extension of this problem in which a fleet of vehicles is available. Given the characteristics of the mentioned application, the vehicles have no capacities but there is a maximum distan…

Financial assets and patrimonial issues in international families

2021

: The paper deals with patrimonial issues in International families and with the European Regulations 1103 and 1104/ 2016 together with regulation 650/2012. The paper particularly focuses on financial assets: Bank Account; Share of Investments Funds; Life Insurance; Virtual assets like criptovalutes; real estate wealth. This perspective implies the need to find the rule governing the succession or the families? patrimonial issues, also taking into account the different rules in the different states concerned of the contracts that govern the circulation of such goods.

Protection of the surviving spouse in French law

2021

While French inheritance law has recently sought to give everyone more freedom to anticipate the transmission of their estate, it still guarantees to the children a reserved portion in his estate. This guarantees the deceased?s children a minimum share in his/her estate. However, the mechanisms protecting this reserve are subject to legal adjustments when spouses wish to organize the protection of the couple?s survivor, either by submitting to a conventional matrimonial regime or by giving themselves gifts that improve the legal succession of the spouse. This ensures a balance between the protection of the spouse and that of the compulsory heirs. Not seeming to be satisfied, several famous …

The impact of direct acting antivirals on hepatitis C virus disease burden and associated costs in four European countries

2021

Eliminació del VHC; Punt d'equilibri; Infecció d'hepatitis C Eliminación del VHC; Punto de equilibrio; Infección de hepatitis C HCV elimination; Break-even; Hepatitis C infection Background and Aims We assessed the clinical and economic impact of direct-acting antiviral (DAA) therapy for hepatitis C virus (HCV) in England, Italy, Romania and Spain. Methods An HCV progression Markov model was developed considering DAA eligibility and population data during the years 2015-2019. The period of time to recover the investment in DAAs was calculated as the cost saved by avoiding estimated clinical events for 1000 standardized treated patients. A delayed treatment scenario because of coronavirus di…

Dažādu inhalējamo kortikosteroīdu devu pretiekaisuma darbība un kombinētās terapijas efektivitātes salīdzinājums pacientiem ar vidēji smagu persistēj…

2003

Adicciones y contexto sociocultural: perspectivas psicosociológicas críticas

2007

De cara a la comprensión del actual consumo juvenil de sustancias psicoactivas, en este trabajo se pretende entender de una forma adecuada y profunda tanto el consumo de drogas como la finalidad última de las campañas antidroga. Para ello se considera fundamental distinguir los diferentes tipos de consumo adictivo y, sobre todo, tener muy presente el contexto sociocultural en que ha tenido y sigue teniendo lugar tal consumo. Finalmente, se pretende utilizar el anterior análisis psicosociológico para desenmascarar los fines políticos y de control social que a menudo tienen las campañas antidrogas, que, por tanto, se convierten en verdaderas cruzadas contra el toxicómano, generalmente joven, …

Astmosil® un Atmosil® ietekme uz daļēji kontrolētu vai nekontrolētu astmu

2018

Pamata informācija: Astma ir kompleksa slimība ar augstiem saslimstības rādītājiem. Tā ir viena no izplatītākajām slimībām, kuras ārstēšanai tiek izmantotas vairākas savstarpēji papildinošas un alternatīvas ārstēšanas formas. Mērķi: Pētījuma mērķis ir izpētīt uztura bagātinātāju Astmosil un Atmosil ietekmi uz dažādiem astmas rādītājiem pacientiem ar mēreni noturīgu daļēji kontrolētu vai nekontrolētu astmu, kuri tiek ārstēti saskaņā ar GINA vadlīniju otro līdz ceturto soli. Metodes un materiāli: Tika veikts 18 nedēļas ilgs perspektīvs, nejaušināts, dubultmaskēts, placebo-kontrolēts, šķērsgriezuma pētījums. 30 pacienti, vecumā no 18 līdz 75 gadiem, tika iedalīti grupās 1:1:1 un pēc nejaušības…