Search results for "STORM"

showing 10 items of 202 documents

Synthesis of polyfluoroalkyl sp2-iminosugar glycolipids and evaluation of their immunomodulatory properties towards anti-tumor, anti-leishmanial and …

2019

Immunomodulatory glycolipids, among which α-galactosylceramide (KRN7000) is an iconic example, have shown strong therapeutic potential in a variety of conditions ranging from cancer and infection to autoimmune or neurodegenerative diseases. A main difficulty for those channels is that they often provoke a cytokine storm comprising both pro- and anti-inflammatory mediators that antagonize each other and negatively affect the immune response. The synthesis of analogues with narrower cytokine secretion-inducing capabilities is hampered by the intrinsic difficulty at controlling the stereochemical outcome in glycosidation reactions, particularly if targeting the α-anomer, which seriously hamper…

Allosteric regulationIminosugar01 natural sciencesImmunomodulation03 medical and health sciencesGlycolipidGlycomimeticDrug DiscoverymedicineLeishmaniasisp38α MAPKCancer030304 developmental biologyInflammationPharmacology0303 health sciences010405 organic chemistryChemistryOrganic ChemistryAutophosphorylationBiological activityGeneral Medicinemedicine.disease0104 chemical sciencessp2-Iminosugar glycolipidsBiochemistryMechanism of actionPolyfluoroalkyl compoundsmedicine.symptomCytokine stormEuropean Journal of Medicinal Chemistry
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Atmosphere-Space Interactions Monitor (ASIM): State of the Art

2014

Atmosphere-Space Interactions Monitor (ASIM) mission is an ESA pay load which will be installed in the Columbus module of the International Space Station (ISS). ASIM is optimized to the observation and monitoring of luminescent phenomena in the upper atmosphere, the so called Transient Luminous Event (TLEs) and Terrestrial Gamma Ray Flashes(TGFs). Both TLEs and TGFs have been discovered recently (past two decades) and opened a new field of research in high energetic phenomena in the atmosphere. We will review the capabilities of ASIM and how it will help researchers to gain deeper knowledge of TGFs, TLEs, their inter-relationship and how they are linked to severe thunderstorms and the pheno…

AtmosphereEngineeringMeteorologybusiness.industrylcsh:TA1-2040International Space StationThunderstormGeneral Earth and Planetary Sciencesbusinesslcsh:Engineering (General). Civil engineering (General)LightningGeneral Environmental ScienceActa Polytechnica CTU Proceedings
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2019

Abstract. The evolution of the tropopause inversion layer (TIL) during cyclogenesis in the North Atlantic storm track is investigated using operational meteorological analysis data (Integrated Forecast System from the European Centre for Medium-Range Weather Forecasts). For this a total of 130 cyclones have been analysed during the months August through October between 2010 and 2014 over the North Atlantic. Their paths of migration along with associated flow features in the upper troposphere and lower stratosphere (UTLS) have been tracked based on the mean sea level pressure field. Subsets of the 130 cyclones have been used for composite analysis using minimum sea level pressure to filter t…

Atmospheric Science010504 meteorology & atmospheric sciences010502 geochemistry & geophysicsAtmospheric sciences01 natural sciencesTroposphereWind shearCyclogenesisExtratropical cycloneCycloneOutflowStorm trackTropopauseGeology0105 earth and related environmental sciencesAtmospheric Chemistry and Physics
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Heating rate profiles and radiative forcing due to a dust storm in the Western Mediterranean using satellite observations

2017

Abstract We analyze the vertically-resolved radiative impact due to a dust storm in the Western Mediterranean. The dust plume travels around 3–5 km altitude and the aerosol optical depth derived by MODIS at 550 nm ranges from 0.33 to 0.52 at the overpass time (13:05 UT). The aerosol radiative forcing (ARF), forcing efficiency (FE) and heating rate profile (AHR) are determined throughout the dust trajectory in shortwave (SW) and longwave (LW) ranges. To do this, we integrate different satellite observations (CALIPSO and MODIS) and detailed radiative transfer modeling. The combined (SW + LW) effect of the dust event induces a net cooling in the studied region. On average, the FE at 22.4° sola…

Atmospheric Science010504 meteorology & atmospheric sciencesLongwaveSolar zenith angleRadiative forcing010502 geochemistry & geophysicsAtmospheric sciences01 natural sciencesPlumeDust stormRadiative transferEnvironmental scienceShortwaveRefractive index0105 earth and related environmental sciencesGeneral Environmental ScienceAtmospheric Environment
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High-speed intensified video recordings of sprites and elves over the western Mediterranean Sea during winter thunderstorms

2010

We report the first intensified high‐speed video images of elves, sprites, and halos observed in Europe. All the events corresponded to winter season thunderstorms over the Mediterranean Sea. The observations comprise many elves generated by both cloud‐to‐ground lightning current polarities. In 8 of the 14 sprite observations we observed an elve previous to the sprite. In three cases we observed also an elve quickly followed by a halo and a sprite. In several observations we observed lightning light before the mesospheric transient luminous event. We present a case where the lightning from cloud tops was visible during the entire event. Thanks to the high‐speed videos and their resolution a…

Atmospheric Science010504 meteorology & atmospheric sciencesMeteorology0207 environmental engineeringSoil Science02 engineering and technologyAquatic ScienceOceanography01 natural sciencesMediterranean seaSprite (lightning)Geochemistry and PetrologyEarth and Planetary Sciences (miscellaneous)Thundersnow020701 environmental engineering0105 earth and related environmental sciencesEarth-Surface ProcessesWater Science and TechnologyEcologyCloud topPaleontologyForestryVideo imageGeophysics13. Climate actionSpace and Planetary ScienceThunderstormLight emissionAtmospheric electricityGeologyJournal of Geophysical Research: Space Physics
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Advances in understanding mineral dust and boundary layer processes over the Sahara from Fennec aircraft observations

2015

Abstract. The Fennec climate programme aims to improve understanding of the Saharan climate system through a synergy of observations and modelling. We present a description of the Fennec airborne observations during 2011 and 2012 over the remote Sahara (Mauritania and Mali) and the advances in the understanding of mineral dust and boundary layer processes they have provided. Aircraft instrumentation aboard the UK FAAM BAe146 and French SAFIRE (Service des Avions Français Instrumentés pour la Recherche en Environnement) Falcon 20 is described, with specific focus on instrumentation specially developed for and relevant to Saharan meteorology and dust. Flight locations, aims and associated met…

Atmospheric Science010504 meteorology & atmospheric sciencesMeteorologyPlanetary boundary layerCONVECTIVE SYSTEMEnvironmental Sciences & EcologyAEROSOL OPTICAL-PROPERTIESMineral dust010502 geochemistry & geophysicsAtmospheric sciences01 natural sciencesCOARSE MODElcsh:ChemistryHaboobDust storm0201 Astronomical and Space SciencesMeteorology & Atmospheric SciencesSatellite imagerySOUTHERN MOROCCO0105 earth and related environmental sciences[PHYS.PHYS.PHYS-AO-PH]Physics [physics]/Physics [physics]/Atmospheric and Oceanic Physics [physics.ao-ph]GBScience & TechnologyHEAT LOWAIRBORNE OBSERVATIONSRETRIEVAL PRODUCTSOzone depletionlcsh:QC1-999PARTICLE-SIZEAERONETBoundary layerlcsh:QD1-99913. Climate action[SDU.STU.CL]Sciences of the Universe [physics]/Earth Sciences/ClimatologyPhysical SciencesWEST-AFRICAN MONSOONEnvironmental science0401 Atmospheric SciencesNORTH-ATLANTIC OCEANLife Sciences & Biomedicinelcsh:PhysicsEnvironmental SciencesAtmospheric Chemistry and Physics
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Observationally Weak TGFs in the RHESSI Data

2019

Abstract Terrestrial gamma ray flashes (TGFs) are sub‐millisecond bursts of high energetic gamma radiation associated with intracloud flashes in thunderstorms. In this paper we use the simultaneity of lightning detections by World Wide Lightning Location Network to find TGFs in the Reuven Ramaty High Energy Solar Spectroscopic Imager (RHESSI) data that are too faint to be identified by standard search algorithms. A similar approach has been used in an earlier paper, but here we expand the data set to include all years of RHESSI + World Wide Lightning Location Network data and show that there is a population of observationally weak TGFs all the way down to 0.22 of the RHESSI detection thresh…

Atmospheric Science010504 meteorology & atmospheric sciences[SDU.STU.GP]Sciences of the Universe [physics]/Earth Sciences/Geophysics [physics.geo-ph]Atmospheric ElectricityPopulationHard radiationAstrophysics01 natural sciencesLightningterrestrial gamma‐ray flahesAerosol and CloudsLatitude0103 physical sciencesEarth and Planetary Sciences (miscellaneous)RHESSIobservationally weakeducation010303 astronomy & astrophysicsResearch Articles0105 earth and related environmental sciencesPhysicseducation.field_of_studyGamma rayNetwork datathunderstormsLightningWorld widehard radiationGeophysicsSpace and Planetary ScienceAtmospheric ProcessesThunderstormResearch ArticleJournal of Geophysical Research: Atmospheres
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Assessing the predictability of Medicanes in ECMWF ensemble forecasts using an object-based approach

2018

The predictability of eight southern European tropical-like cyclones, seven of which Medicanes, is studied evaluating ECMWF operational ensemble forecasts against operational analysis data. Forecast cyclone trajectories are compared to the cyclone trajectory in the analysis by means of a dynamic time warping technique, which allows to find a match in terms of their overall spatio-temporal similarity. Each storm is treated as an object and its forecasts are analysed using metrics that describe intensity, symmetry, compactness, and upper-level thermal structure. This object-based approach allows to focus on specific storm features, while tolerating their shifts in time and space to some exten…

Atmospheric ScienceDynamic time warping010504 meteorology & atmospheric sciencesMeteorologyFOS: Physical sciencesStorm01 natural sciences010305 fluids & plasmasPhysics - Atmospheric and Oceanic Physics0103 physical sciencesAtmospheric and Oceanic Physics (physics.ao-ph)Data analysisTrajectoryJumpCycloneEnvironmental sciencePredictabilityLead timePhysics::Atmospheric and Oceanic Physics0105 earth and related environmental sciences
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Climatology of convective density currents in the southern foothills of the Atlas Mountains

2010

Density currents fed by evaporationally cooled air are an important dust storm generating feature and can constitute a source of moisture in arid regions. Recently, the existence of such systems has been demonstrated for the area between the High Atlas Mountains and the Sahara desert in southern Morocco on the basis of case studies. Here, a climatological analysis is presented that uses data from the dense climate station network of the IMPETUS project (An Integrated Approach to the Efficient Management of Scarce Water Resources in West Africa) for the 5 year period 20022006. Objective criteria mainly based upon abrupt changes in wind and dew point temperature are defined to identify possib…

Atmospheric ScienceEcologyPaleontologySoil ScienceForestryAquatic ScienceOceanographyAtmospheric temperatureAridWind speedAtmosphereGeophysicsDew pointSpace and Planetary ScienceGeochemistry and PetrologyDust stormDiurnal cycleClimatologyEarth and Planetary Sciences (miscellaneous)Environmental scienceAir massEarth-Surface ProcessesWater Science and TechnologyJournal of Geophysical Research
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Blue Flashes as Counterparts to Narrow Bipolar Events: the Optical Signal of Shallow In-Cloud Discharges

2021

This is an open access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Atmospheric ScienceNarrow bipolar events (NBEs)010504 meteorology & atmospheric sciencesMeteorologybusiness.industryCloud computingAstrophysics::Cosmology and Extragalactic Astrophysics010502 geochemistry & geophysics01 natural sciencesLightningSignalLightningGeophysicsSpace and Planetary Science13. Climate actionEarth and Planetary Sciences (miscellaneous)ThunderstormbusinessGeneralLiterature_REFERENCE(e.g.dictionariesencyclopediasglossaries)StreamerBlue luminous events (BLUEs)GeologyAstrophysics::Galaxy Astrophysics0105 earth and related environmental sciences
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