Search results for "STRESS"
showing 10 items of 6278 documents
Identification of Critical Genes for Growth in Olive Brine by Transposon Mutagenesis of Lactobacillus pentosus C11
2013
ABSTRACT Olive brine represents a stressful environment due to the high NaCl concentration, presence of phenolic compounds known as antimicrobials, and low availability of nutrients. Thus, only a few strains of lactic acid bacteria (LAB) are adapted to grow in and ferment table olives. To identify the mechanisms by which these few strains are able to grow in olive brine, Lactobacillus pentosus C11, a particularly resistant strain isolated from naturally fermented table olives, was mutagenized by random transposition using the P junc -TpaseIS 1223 system (H. Licandro-Seraut, S. Brinster, M. van de Guchte, H. Scornec, E. Maguin, P. Sansonetti, J. F. Cavin, and P. Serror, Appl. Environ. Microb…
The Chaperone Activity of Clusterin is Dependent on Glycosylation and Redox Environment
2014
Background/Aims: Clusterin (CLU), also known as Apolipoprotein J (ApoJ) is a highly glycosylated extracellular chaperone. In humans it is expressed from a broad spectrum of tissues and related to a plethora of physiological and pathophysiological processes, such as Alzheimer's disease, atherosclerosis and cancer. In its dominant form it is expressed as a secretory protein (secreted CLU, sCLU). During its maturation, the sCLU-precursor is N-glycosylated and cleaved into an α- and a β-chain, which are connected by five symmetrical disulfide bonds. Recently, it has been demonstrated that besides the predominant sCLU, rare intracellular CLU forms are expressed in stressed cells. Since these for…
Manipulating mtDNA in vivo reprograms metabolism via novel response mechanisms.
2019
Mitochondria have been increasingly recognized as a central regulatory nexus for multiple metabolic pathways, in addition to ATP production via oxidative phosphorylation (OXPHOS). Here we show that inducing mitochondrial DNA (mtDNA) stress in Drosophila using a mitochondrially-targeted Type I restriction endonuclease (mtEcoBI) results in unexpected metabolic reprogramming in adult flies, distinct from effects on OXPHOS. Carbohydrate utilization was repressed, with catabolism shifted towards lipid oxidation, accompanied by elevated serine synthesis. Cleavage and translocation, the two modes of mtEcoBI action, repressed carbohydrate rmetabolism via two different mechanisms. DNA cleavage activ…
Ecohydrology in Mediterranean areas: a numerical model to describe growing seasons out of phase with precipitations
2008
The probabilistic description of soil moisture dynamics is a relatively new topic in hydrology. The most common ecohydrological models start from a stochastic differential equation describing the soil water balance, where the unknown quantity, the soil moisture, depends both on spaces and time. Most of the solutions existing in literature are obtained in a probabilistic framework and under steady-state condition; even if this last condition allows the analytical handling of the problem, it has considerably simplified the same problem by subtracting generalities from it. <br><br> The steady-state hypothesis, appears perfectly applicable in arid and semiarid climatic areas like th…
Towards Low-Cost Pavement Condition Health Monitoring and Analysis Using Deep Learning
2020
Governments are faced with countless challenges to maintain conditions of road networks. This is due to financial and physical resource deficiencies of road authorities. Therefore, low-cost automated systems are sought after to alleviate these issues and deliver adequate road conditions for citizens. There have been several attempts at creating such systems and integrating them within Pavement management systems. This paper utilizes replicable deep learning techniques to carry out hotspot analyses on urban road networks highlighting important pavement distress types and associated severities. Following this, analyses were performed illustrating how the hotspot analysis can be carried out to…
The phantoms of the opera—Stress offstage and stress onstage
2021
During opera performance singers deliver vocally demanding roles, follow a conductor, portray emotions of a musical work, act, dance, and engage with costumes, sets and props before an audience. Hence, opera performance is a stressful experience. This study examined different types of stress experiences by measuring the trajectories of 10 opera trainees’ heart rate variability (HRV) during two performances, covering onstage and offstage periods. We explored connections between HRV, self-reported stress measures, and expert-rated difficulty of the performed roles. We discovered that opera trainees had lower HRV and thus experienced greater physiological stress, while onstage compared to off…
Dienasgrāmatas metode darba stresa mazināšanai
2019
Šī maģistra darba mērķis bija apkopojot līdz šim izpētīto informāciju par uztverto stresu, stresu darbā, un par dienasgrāmatas metodi, tās dažādību un izmantošanu, kā arī apkopojot informāciju par šo konstruktu saistībām, realizēt kvantitatīvu salīdzinošu pētījumu ar eksperimentālu dizainu, lai noskaidrotu vai dienasgrāmatas metode ir efektīva, lai mazinātu stresu darbā; vai strukturēta dienasgrāmata ir efetkīvāka par nestrukturētu dienasgrāmatas formātu, kā arī kādi ir biežāk identificētie stresori darba vidē. Pētījumā piedalījās 95 respondenti (eksperimentālā grupa, kura pildīja strukturētu dienasgrāmatu n=30, eksperimentālā grupa, kura pildīja brīvas formas dienasgrāmatu n=32, kontroles …
Psihosociālo darba vides risku saistība ar izglītības iestāžu vadītāju darbspējām
2018
„Psihosociālie darba vides risku saistība ar izglītības iestāžu vadītāju darbspējām”. Darba autore: Elīna Dreimane. Darba zinātniskais vadītājs: Dr.sc.admin., asoc.prof. Henrijs Kaļķis. Darbs izklāstīts uz 83 lpp., ietver 45 attēlus, 4 tabulas, 4 pielikumus, 47 informatīvos avotus. Maģistra darba struktūra veidota no četrām daļām. Pirmajā daļā apkopota un analizēta literatūra par vispārējiem darba vides riskiem izglītības iestāžu vadītāju darbā, kā arī psihosociālo risku būtība, ietekme un iespējamās sekas. Otrajā daļā norādītas izmantotās metodes vispārējo un psihosociālo risku noteikšanai. Trešajā daļā identificēti un analizēti vispārējie un psihosociālie darba vides riski pēc izmantoto m…
Romanian adoptive families: Stressors, coping strategies and resources
2012
Abstract This study was undertaken to describe the stressors that the Romanian adoptive families confront with, during the different stages of their life cycle, the coping strategies that they adopt and the resources needed and available to them to respond to these stressors. It was used a purposive sample, composed of nine mothers that have adopted children between five months and five years old. The technique used for the data collection was the narrative interview. The main emergent themes in the interviews have been: the desire to have a child and the infertility; the adoption procedure; the uncertainty regarding the moment of placement; the instant adoption of the parental role-status;…
Selection of Debaryomyces hansenii isolates as starters in meat products based on phenotypic virulence factors, tolerance to abiotic stress condition…
2021
Debaryomyces hansenii is a yeast widely used in meat fermentations as starter for the purpose of improving the aromatic quality of the final product. However, it has not been the subject of an extensive study regarding phenotypic characteristics important for starter selection, such as the capacity to grow at abiotic stress conditions occurring during fermentation, the ability to generate desirable aromas and the absence of virulence traits in yeasts.