Search results for "STRESS"

Glial Chloride Homeostasis Under Transient Ischemic Stress

2021

High water permeabilities permit rapid adjustments of glial volume upon changes in external and internal osmolarity, and pathologically altered intracellular chloride concentrations ([Cl–]int) and glial cell swelling are often assumed to represent early events in ischemia, infections, or traumatic brain injury. Experimental data for glial [Cl–]int are lacking for most brain regions, under normal as well as under pathological conditions. We measured [Cl–]int in hippocampal and neocortical astrocytes and in hippocampal radial glia-like (RGL) cells in acute murine brain slices using fluorescence lifetime imaging microscopy with the chloride-sensitive dye MQAE at room temperature. We observed s…

Hemodynamic Changes During Physiological and Pharmacological Stress Testing in Healthy Subjects, Aortic Stenosis and Aortic Coarctation Patients–A Sy…

2019

Introduction: Exercise testing has become a diagnostic standard in the evaluation and management of heart disease. While different methods of exercise and pharmacological stress testing exist, only little is known about their comparability. We aimed to assess hemodynamic changes during dynamic exercise, isometric exercise, and dobutamine stress testing at different stress intensities in healthy subjects and patients with aortic stenosis (AS) and aortic coarctation (CoA).Methods: A systematic literature search (PROSPERO 2017:CRD42017078608) in MEDLINE of interventional trials was conducted to identify eligible studies providing evidence of changes in hemodynamic parameters under different st…

Novel Perspectives in the Detection of Oral and Nasal Oxidative Stress and Inflammation in Pediatric United Airway Diseases

2010

United airway disease (UAD) concept proposed that asthma and rhinitis are both different clinical manifestation of a single inflammatory process. The aim of this study is to assess in upper and lower airways the level of inflammation and oxidative stress and to investigate the relationship between biomarkers in persistent allergic rhinitis (PER) and in concomitant asthma with PER. By a crosssectional study we measured oral and nasal (FENO) and oral and nasal EBC 8-isoprostane, LTB4 and PGE2 in children with PER (n=14) and with PER and concomitant intermittent asthma (IA; n=25), mild persistent asthma (mA; n=28), moderate persistent asthma (MA; n=13) and in Healthy Controls (HCs; n=13). Oral…

Empīriskajā metodē izstrādāto aktivitāšu ietekme angļu valodas runātprasmes apguvei 11. klases skolēniem Rīgas tehnikumā

2019

Diplomdarbā tiek pētīts, kā empīriskajā metodē izstrādātās aktivitātes uzlabo skolēnu runas prasmes, samazina stresu un baiļu sajūtu no runāšanas. Mērķis ir izstrādāt uz empīrisko metodi balstītas apmācību aktivitātes un izpētīt, kā tas veicina skolnieku runas prasmju attīstīšanu un vai motivē aktīvi piedalīties apmācības procesā. Teorētiskajā daļā ir pētīta runas prasme, empīriskās apmācības teorija un tās pielietošana apmācībās procesā. Empīriskajā daļā atspoguļoti metodes pielietošanas rezultāti. Sākotnējās pārbaudes rezultātu analīze, salīdzinot ar starppārbaudes un gala pārbaudes rezultātiem, pierādīja, ka skolnieku grupai, kuri bija iesaistīti eksperimentā, uzlabojās runas prasme, sam…

Progressi sperimentali e numerici nella valutazione dell'integrita strutturale dei solidi mediante Thermoelastic Stress Analysis

2023

Stability of Embankments Resting on Foundation Soils with A Weak Layer

2021

The presence of weak layers in geotechnical systems, including soil or rock masses, both natural and man-made, is more frequent than is normally believed. Weak layers can affect both failure mechanisms, in drained and in undrained conditions, as well as in static and seismic conditions, and the safety factor. In the present study, conducted numerically using the finite-element method (FEM) Plaxis 2D code, the influence of a horizontal thin weak layer on stress and strain distribution, on failure mechanisms and on the overall stability of an embankment was evaluated. The results obtained prove that when the weak layer is located at a significant depth from the foundation plane, the failure m…

Fake news and patient-family-physician interaction in critical care: concepts, beliefs and potential countermeasures

2020

Fake news has been defined as fabricated information mimicking media content in form but not in organizational process or intent. Science and medicine are deeply affected by this increasing phenomenon. Critical care represents a hot spot for fake news due to the high risk of conflictive communication, the rapid turnaround of clinical news and high prevalence of unpleasant information. Communication with patients' relatives is one of the hardest aspects. The relationship between physicians and families is pivotal to improve relatives' comfort, and reduce anxiety and pain. Fake news may undermine this relationship, posing an alternative truth between the critical care physician and relatives,…

The Role of Individual- and Macro-Level Social Determinants on Young Adolescents’ Psychosomatic Complaints

2011

This study examines the social determinants of psychosomatic complaints in young adolescents. Using data from the Health Behaviour in School-aged Children (HBSC) study, psychosomatic complaints are studied in 98,773 adolescents (11- and 13-year-olds; 48% 11-year-olds, 52% 13-year-olds; 52% females, 48% males) from 34 European countries. Individual-level determinants, including family-, peer- and school-related factors as well as country-level determinants (Human Development Index [HDI]) are considered. In line with existing evidence, results revealed more psychosomatic complaints in young adolescents experiencing stress inducing familial-, peer- and school-related factors. Negative effects…

Stress darbā un veselības veicināšanas pasākumi farmaceitiem

2018

“Stress darbā un veselības veicināšanas pasākumi farmaceitiem.” Darba autore Linda Grabovska. Darba zinātniskā vadītāja: Dr. med., asociētā profesore Ženija Roja. Maģistra darbs izklāstīts uz 70 lpp., ietver 21 attēlu, 9 tabulas, 7 pielikumus, 56 informatīvos avotus. Maģistra darbā ir pētīti stresa indikatori aptiekās strādājošajiem darbiniekiem un kā kontroles grupa piesaistīti dažādu nozaru biroja darbinieki. Stress ir bieža sastopama parādība darba vietās, kas negatīvi ietekmē darbinieka veselību, ko bieži izraisa darba vides riski un psihoemocionālā slodze. Darbs sastāv no trīs daļām. Pirmajā daļā analizēta pieejamā literatūra par pētām…

Adaptation and Preliminary Validation of the Fear of Coronavirus Vaccination Scale in the Prospective Study among a Representative Sample of Polish, …

2022

Although concerns about harm and side effects are among the most important factors determining vaccine hesitancy, research on the fear of vaccination is sparse. The purpose of this study is a validation the Fear of Coronavirus Vaccination Scale (FoCVVS), adapted from the Fear of COVID-19 Scale. A representative sample of 1723 young adults aged 20–40 from Poland, Israel, Slovenia, and Germany participated during two time-points of the third COVID-19 pandemic wave. The online survey included demographic variables and several well-being dimensions, including gender, vaccination status, fear of coronavirus (FoCV-19S), physical health (GSRH), life satisfaction (SWLS), and perceived stress (PSS-1…