Search results for "SUBTYPES"

showing 3 items of 33 documents

In vivo metabolism of LDL subfractions in patients with heterozygous FH on statin therapy

2004

LDL can be subfractionated into buoyant (1.020-1.029 g/ml(-1)), intermediate (1.030-1.040 g/ml(-1)), and dense (1.041-1.066 g/ml(-1)) LDLs. We studied the rebound of these LDL-subfractions after LDL apheresis in seven patients with heterozygous familial hypercholesterolemia (FH) regularly treated by apheresis (58 +/- 9 years, LDL-cholesterol = 342 +/- 87 mg/dl(-1), triglycerides = 109 +/- 39 mg/dl(-1)) and high-dose statins. Apolipoprotein B (apoB) concentrations were measured in LDL subfractions immediately after and on days 1, 2, 3, 5, and 7 after apheresis. Compartmental models were developed to test three hypotheses: 1) that dense LDLs are derived from the delipidation of buoyant and in…

medicine.medical_specialtyVery low-density lipoproteinApolipoprotein Blow density lipoprotein metabolismFamilial hypercholesterolemiaQD415-436Biochemistrychemistry.chemical_compoundEndocrinologyInternal medicinerebound kineticsmedicinesmall dense low density lipoproteinsdensity gradient ultracentrifugationbiologyfamilial hypercholesterolemiaChemistryCholesterollow density lipoprotein subtypesCell BiologyMetabolismmedicine.diseaseEndocrinologyApheresisLDL apheresisbiology.proteinDensity gradient ultracentrifugationlipids (amino acids peptides and proteins)Journal of Lipid Research
researchProduct

Association of child maltreatment subtypes and long-term physical health in a German representative sample

2018

ABSTRACT Background: Child maltreatment is a major public problem, associated with enormous consequences on the individual and socioeconomic level. Studies show a clear impact of child maltreatment on long-term physical health. However, there is a lack of analyses comprising a wide variety of subtypes of maltreatment and addressing cumulative effects of different maltreatment subtypes experienced during childhood on physical health. Objective: The objective of this analysis was to assess the association of different subtypes and the intensity of child maltreatment with long-term physical health outcomes. Methods: In a cross-sectional observational approach, a representative sample of the Ge…

obesityPsychological interventionObesidadChild abuse and neglectInfarto al Miocardio癌症心肌梗塞0302 clinical medicinelcsh:PsychiatryEnfermedad pulmonar obstructiva crónica030212 general & internal medicineStrokeClinical Research Articlediabetes05 social sciencesCáncerstrokemyocardial infarction• Studies addressing cumulative effects of different child maltreatment subtypes on physical health are sparse especially those comprising emotional and physical neglect.• Odds for obesity diabetes cancer hypertension chronic obstructive pulmonary disease history of myocardial infarction and stroke increased when any kind of child maltreatment was reported.• Growing intensity of each maltreatment subtype was associated with higher rates of all assessed conditions.• Odds for all conditions increased with increasing number of maltreatment subtypes that were experienced.Hipertensión Arterial050104 developmental & child psychologyClinical psychology虐待和忽视儿童medicine.medical_specialtyhypertension高血压lcsh:RC435-571中风physical health outcomesOddschronic obstructive pulmonary disease童年虐待肥胖糖尿病03 medical and health sciencesmedicinecancer0501 psychology and cognitive sciencesAbuso infantil y negligenciaSocioeconomic statusConsecuencias de Salud Físicabusiness.industryPublic healthCTQ treeApoplejíamedicine.diseaseObesity身体健康结果Maltrato infantil慢性阻塞性肺疾病Observational studybusinesschild maltreatmentEuropean Journal of Psychotraumatology
researchProduct

Nieru audzēju klīniski morfoloģiskais raksturojums

2020

Saslimstība ar ļaundabīgajiem nieru audzējiem palielinās katru gadu, visizteiktāk tas vērojams pasaules attīstītajās valstīs, kā arī Latvijā. Nieru šūnu karcinoma ir viens no visbiežākajiem ļaundabīgajiem nieru audzējiem. Agrīnajās stadijās nieru šūnu karcinomai nav raksturīga kāda konkrēta simptomātika un lielākajā daļā gadījumu, tā tiek diagnosticēta netīši- veicot izmeklējumus kādas citas saslimšanas gadījumā. Pēc tam, kad audzējs ir ticis diagnosticēts, ir būtiski izvērtēt pacienta vispārējo stāvokli un riska faktorus, no kā ir atkarīga pacientu kopējā dzīvildze un recidīva risks. Ja iespējams, noteikt histoloģisko nieru šūnu karcinomas subtipu un ņemot vērā šos faktorus, izvēlēties pie…

renal cell carcinomanieru šūnu karcinomarecidīvshistological subtypeshistoloģiskie subtipiMedicīna
researchProduct