Search results for "SUE"

Water Dynamics in Biological Systems investigated using Neutron Scattering Techniques

Living systems can not survive in absence of the water environments which play a fundamental role in living functions. Thus in the scienti?c community many studies were and are addressed to characterize water and its dynamics properties in biological systems. However, a clear description of water in such systems has been not reached yet. In fact, the investigations performed with di?erent techniques - those based on Nuclear Magnetic Resonance or those based on Neutron Scattering - look at di?erent di?usive motions and interactions water-biomolecules, leading controversial results and hence generating many debates between scientists. In this thesis we support the idea that two water populati…

Inhibition of Rac1 signaling by lovastatin protects against anthracycline-induced cardiac toxicity

2011

Normal tissue damage limits the efficacy of anticancer therapy. For anthracyclines, the clinically most relevant adverse effect is cardiotoxicity. The mechanisms involved are poorly understood and putative cardioprotectants are controversially discussed. Here, we show that the lipid-lowering drug lovastatin protects rat H9c2 cardiomyoblasts from doxorubicin in vitro. Protection by lovastatin is related to inhibition of the Ras-homologous GTPase Rac1. It rests on a reduced formation of DNA double-strand breaks, resulting from the inhibition of topoisomerase II by doxorubicin. Doxorubicin transport and reactive oxygen species are not involved. Protection by lovastatin was confirmed in vivo. I…

Awareness of radiation protection issue in paediatric trainees. A questionnaire study.

2011

Invasive breast cancer in ectopic axillary breast tissue — case report

2021

Breast cancer is the most commonly diagnosed malignancy in women in Poland. Rare, unusual forms of breast cancer remain a diagnostic problem. The incidence of ectopic breast glandular tissue in the general population varies between 0.4 and 6%. The same abnormalities and diseases as in the anatomical mammary gland may develop in this tissue. Breast cancer may develop as well. We present the case of a 36-year-old woman, who went to the doctor because of a nodule in the right armpit presented for 2 years. The patient was referred to a surgeon with suspicion of an epidermal cyst. The lesion was surgically removed and in the histopathological examination, the diagnose was: invasive breast cancer…

Enterobacter cloacae administration induces hepatic damage and subcutaneous fat accumulation in high-fat diet fed mice.

2018

Accumulating evidence indicates that gut microbiota plays a significant role in obesity, insulin resistance and associated liver disorders. Family Enterobacteriaceae and especially Enterobacter cloacae strain B29 have been previously linked to obesity and hepatic damage. The underlying mechanisms, however, remain unclear. Therefore, we comprehensively examined the effects of E. cloacae subsp. cloacae (ATCC® 13047™) administration on host metabolism of mice fed with high-fat diet (HFD). C57BL/6N mice were randomly divided into HFD control, chow control, and E. cloacae treatment groups. The E. cloacae treatment group received live bacterial cells in PBS intragastrically twice a week, every ot…

Topological canal foliations

2019

Regular canal surfaces of $\mathbb{R}^3$ or $\mathbb{S}^3$ admit foliations by circles: the characteristic circles of the envelope. In order to build a foliation of $\mathbb{S}^3$ with leaves being canal surfaces, one has to relax the condition “canal” a little (“weak canal condition”) in order to accept isolated umbilics. Here, we define a topological condition which generalizes this “weak canal” condition imposed on leaves, and classify the foliations of compact orientable 3-manifolds we can obtain this way.

Repeated kidney re-transplantation—the Eurotransplant experience: a retrospective multicenter outcome analysis

2020

Transplant international (2020). doi:10.1111/tri.13569

Communication et médiation par le toucherdans quelques expositions de sciences : Limites et contraintes dans l’expérience des visiteurs

2016

This communication deals with the “general public” of visitors to a number of interactive exhibits that accord a direct or indirect role to the sense of touch in knowledge mediation and interpretation. The role of touch is discussed in terms of its limitations and constraints in communication situations. The social mobilizations of touch are not immediately evident; what are the conditions under which visitors actually use touch in experiencing an exhibit? What connections with other signifiers are the most conducive to reception? This qualitative research relies on observation and interviews. Apprehension of interactive objects appears to be dependent on the surrounding setting of sociabil…

Intérêts et limites de l’electrostimulation pour l’évaluation, le traitement et la prévention des altérations neuromusculaires induites par l’exercic…

2004

L'objectif de ce travail était d'une part d'étudier les altérations neuromusculaires induites par un exercice excentrique sollicitant les muscles extenseurs du genou, et d'autre part d'étudier l'efficacité de l'électrostimulation (ES) comme moyen d'évaluation, de traitement et de prévention de ces altérations. La première étude de ce travail consistait à évaluer les contributions des mécanismes centraux et périphériques à la diminution de la contraction maximale volontaire observée après l'exercice excentrique. La fatigue basse fréquence (FBF) et la fatigue centrale expliquaient principalement la diminution du moment maximal volontaire après l'exercice excentrique. Le but de la deuxième étu…

Complejidad, reflexividad y autoetnografía. Las posibilidades de la investigación narrativa en la mejora de la práctica profesional

2015

Desde hace unos años es evidente la creciente dificultad para intervenir desde los servicios sociales ante situaciones que se presentan en un contexto de multiplicidad e inestabilidad. Esta realidad, tradicionalmente concebida como una expresión de la complejidad de la sociedad, puede ser también observada desde un enfoque particular y poco conocido de los problemas sociales: el de los wicked problem, que nos acerca a otra forma de entenderlos. Sus cualidades nos llevan a reflexionar sobre la posibilidad de que coexistan ciertos límites en la capacidad de las organizaciones y profesionales para obtener resultados que mejoren significativamente las situaciones a las que se enfrentan. Al mis…