Search results for "SUPERIOR"
showing 10 items of 714 documents
Role of two sequence motifs of mesencephalic astrocyte-derived neurotrophic factor in its survival-promoting activity
2015
AbstractMesencephalic astrocyte-derived neurotrophic factor (MANF) is a prosurvival protein that protects the cells when applied intracellularly in vitro or extracellularly in vivo. Its protective mechanisms are poorly known. Here we studied the role of two short sequence motifs within the carboxy-(C) terminal domain of MANF in its neuroprotective activity: the CKGC sequence (a CXXC motif) that could be involved in redox reactions, and the C-terminal RTDL sequence, an endoplasmic reticulum (ER) retention signal. We mutated these motifs and analyzed the antiapoptotic effect and intracellular localization of these mutants of MANF when overexpressed in cultured sympathetic or sensory neurons. …
Color Doppler ultrasonography of the eye and orbit
1993
Color Doppler imaging is the recent development in ultrasonography that allows simultaneous two-dimensional structural imaging in Doppler evaluation of blood flow. With this technique, it is possible for the first time to indirectly display the fine orbital vessels such as the ophthalmic artery and its branches, the central retinal artery, the posterior ciliary artery, and the lacrimal artery. Also, the display of venous structures such as the superior ophthalmic vein, the vortex vein, and the central retinal vein is possible. In addition to the qualitative display of those vessels, the hemodynamics in those vessels can be quantitatively assessed by looking at the Doppler spectrum and deter…
The role of the claustrum in the bilateral control of frontal oculomotor neurons in the cat.
1991
The effect of claustrum (CL) stimulation on the spontaneous unitary activity of ipsi and contralateral frontal oculomotor neurons, was studied in chloralose-anaesthetized cats. A total of 205 units was bilaterally recorded in the medial oculomotor area, homologous of the primate "frontal eye fields"; 127 neurons were identified as projecting to the superior colliculus; for 33 of these last units stimulation of the ipsilateral CL provoked an excitatory effect lasting 10-25 ms and appearing with a latency of 5-15 ms; on 8 units the excitatory effect was followed by an inhibition lasting 100-250 ms. Ninety-eight of the 127 neurons were also tested through activation of the contralateral CL: 13…
Alterations of regional cerebral blood flow and oxygen saturation in a rat sinus-vein thrombosis model.
1996
Background and Purpose The pathophysiology of sinus-vein thrombosis (SVT) in patients and experimental animals is still poorly understood. This study was designed to examine and further elucidate the pathophysiological sequence of events, especially the relationship between local and regional blood flow and hemoglobin oxygen saturation (HbSO 2 ) detected at identical locations. The use of both parameters as outcome indicators should be compared. Methods SVT was induced by ligation of the superior sagittal sinus (SSS) and slow injection of kaolin-cephalin suspension into the SSS in rats. Regional cerebral blood flow (rCBF) was assessed by laser-Doppler flowmetry together with regional HbSO …
Noninvasive evaluation of the celiac trunk and superior mesenteric artery with multislice CT in patients with chronic mesenteric ischaemia.
2008
This study sought to assess the role of multislice computed tomography (MSCT) in patients with suspected chronic mesenteric ischaemia (CMI). Forty-five patients (29 men; mean age 68) underwent MSCT angiography of the abdomen for suspected CMI (main clinical finding: postprandial abdominal pain). The scan protocol was detectors/collimation 16/0.75 mm; feed 36 mm/s; rotation time 500 ms; increment 0.4 mm; 120-150 mAs and 120 kVp. A volume of 80 ml of contrast material was administered through an antecubital vein (rate 4 ml/s), followed by 40 ml of saline (rate 4 ml/s). Images were analysed on the workstation with different algorithms (axial image scrolling, multiplanar reconstructions, maximu…
Cerebral Dynamics during the Observation of Point-Light Displays Depicting Postural Adjustments
2017
Objective: As highly social creatures, human beings rely part of their skills of identifying, interpreting, and predicting the actions of others on the ability of perceiving biological motion. In the present study, we aim to investigate the electroencephalographic (EEG) cerebral dynamics involved in the coding of postural control and examine whether upright stance would be codified through the activation of the temporal-parietal cortical network classically enrolled in the coding of biological motion. Design: We registered the EEG activity of 12 volunteers while they passively watched point light displays (PLD) depicting quiet stable (QB) and an unstable (UB) postural situations and their r…
Identification of the conceptual, procedural and attitudinaldimensions of scientific activity by trainee teachers
2021
Es importante que los maestros y maestras en formación lleguen a interiorizar las características básicas del trabajo científico, es decir que la actividad científica no solamente se relaciona con leyes, principios, conceptos (dimensión conceptual)... sino que también contempla otras dimensiones esenciales como son la procedimental y la actitudinal. De lo contrario, en su futuro como docentes no las tendrán en cuenta, contribuyendo a visiones reduccionistas y empobrecidas de la actividad científica. Por ello,la presente investigación pretende determinar si los maestros y maestras en formación son capaces de reconocer las tres dimensiones (conceptual, procedimental y actitudinal) de la activ…
Uso de blogs en Ciencias de la Actividad Física y el Deporte
2011
Se describe la experiencia de un proyecto de innovación educativa que consistió en el diseño, desarrollo y evaluación de diversos usos de blogs y que se desarrolló en la Universitat de València, durante el curso académico 2009-10. El análisis refleja la heterogeneidad con la que los diferentes profesores dieron respuesta a los problemas específicos planteados en sus materias. La principal conclusión es que esta flexibilidad en el uso de los blogs supone una singular ventaja para la innovación en educación superior centrada en el aprendizaje de los estudiantes.
Investigación en el aula: evaluación de la metodología de aprendizaje basado en problemas en la asignatura de Corrosión
2020
[ES] La metodología de Aprendizaje Basado en Problemas (ABP) se introdujo por primera vez en un curso de Corrosión del Master de Ingeniería Química de la Universitat Politècnica de València, durante el curso 2018-2019. Se diseñaron y presentaron diferentes problemas relacionados con todos estos conceptos como metodología de aprendizaje basado en problemas. Para evaluar el empleo de este tipo de metodología activa se plantea la elaboración de una encuesta a los estudiantes de manera anónima e individual y la realización de una matriz de escenarios presentes y futuros para la asignatura de forma grupal. Es importante señalar que a pesar de que para muchos de los estudiantes (67%) esta era la …
La voz del estudiante en la evaluación del aprendizaje: un camino por recorrer en la universidad
2012
During 2009/2010, the current research was conducted with the aim of analysing student and teaching staff on regarding student participation in assessment. A content analysis of 76 subject outlines was carried out, and then 40 member of the teaching staff and 614 university students were surveyed. The results of the content analysis prove there is a shortage of information about and programming for student participation in assessment. Durante el curso 2009/2010 se llevó a cabo esta investigación con el objetivo de analizar la opinión y perspectiva que profesores y estudiantes universitarios tienen sobre la participación de estos últimos en el proceso de evaluación. Se realizó un análisis de…